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R-IMPP

Product Name
R-IMPP
CAS No.
2133832-83-2
Chemical Name
R-IMPP
Synonyms
R-IMPP;PF-00932239 (R-IMPP);R-IMPP, 10 mM in DMSO;Benzenepropanamide, N-1-isoquinolinyl-4-methoxy-N-(3R)-3-piperidinyl-;(R)-N-(Isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide;Serine endopeptidases,PF-00932239,PF 00932239,inhibit,Ser/Thr Protease,RIMPP,R-IMPP,Inhibitor,Threonine proteases,R IMPP,PF00932239,Serine proteases
CBNumber
CB13155117
Molecular Formula
C24H27N3O2
Formula Weight
389.49
MOL File
2133832-83-2.mol
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R-IMPP Property

Boiling point:
594.4±50.0 °C(Predicted)
Density 
1.186±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: 1 mg/ml; DMSO: 10 mg/ml
form 
A crystalline solid
pka
9.14±0.10(Predicted)
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
20861
Product name
(R)-IMPP
Packaging
1mg
Price
$73
Updated
2024/03/01
Cayman Chemical
Product number
20861
Product name
(R)-IMPP
Packaging
25mg
Price
$1075
Updated
2024/03/01
Cayman Chemical
Product number
20861
Product name
(R)-IMPP
Packaging
5mg
Price
$288
Updated
2024/03/01
Cayman Chemical
Product number
20861
Product name
(R)-IMPP
Packaging
10mg
Price
$539
Updated
2024/03/01
ChemScene
Product number
CS-7579
Product name
R-IMPP
Purity
99.36%
Packaging
50mg
Price
$680
Updated
2021/12/16
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R-IMPP Chemical Properties,Usage,Production

Description

(R)-IMPP is a cell-permeable inhibitor of the secretion of proprotein convertase subtilisin/kexin type 9 (PCSK9; IC50 = 4.8 μM). It promotes the uptake of LDL cholesterol in hepatoma cells by increasing LDL receptor levels. (R)-IMPP apparently impairs PCSK9 secretion by causing transcript-dependent inhibition of PCSK9 translation.

R-IMPP Preparation Products And Raw materials

Raw materials

Preparation Products

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R-IMPP Suppliers

China 32 India 1 United States 7 Global 40
A.J Chemicals
Tel
--
Fax
--
Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58

2133832-83-2, R-IMPPRelated Search:


  • R-IMPP
  • Benzenepropanamide, N-1-isoquinolinyl-4-methoxy-N-(3R)-3-piperidinyl-
  • PF-00932239 (R-IMPP)
  • (R)-N-(Isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide
  • Serine endopeptidases,PF-00932239,PF 00932239,inhibit,Ser/Thr Protease,RIMPP,R-IMPP,Inhibitor,Threonine proteases,R IMPP,PF00932239,Serine proteases
  • R-IMPP, 10 mM in DMSO
  • 2133832-83-2