ChemicalBook > CAS DataBase List > (S)-ethyl 2-(((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate

(S)-ethyl 2-(((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate

Product Name
(S)-ethyl 2-(((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate
CAS No.
1064684-30-5
Chemical Name
(S)-ethyl 2-(((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate
Synonyms
Modafinil Impurity 13;sofosbuvir Ethyl ester imp;Sofosbuvir ethyl ester impuriy;L-Alanine, N-[(2'R)-2'-deoxy-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-, ethyl ester;(S)-2-{[(2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-ylmethoxy](phenoxy)phosphorylamino}propionicacidethylester;(S)-ethyl 2-(((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate;Ethyl sofosbuvirQ: What is Ethyl sofosbuvir Q: What is the CAS Number of Ethyl sofosbuvir Q: What is the storage condition of Ethyl sofosbuvir Q: What are the applications of Ethyl sofosbuvir
CBNumber
CB13158734
Molecular Formula
C21H27FN3O9P
Formula Weight
515.43
MOL File
1064684-30-5.mol
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(S)-ethyl 2-(((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate Property

Density 
1.44±0.1 g/cm3(Predicted)
pka
9.39±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
S675635
Product name
SofosbuvirO-DesisopropylO-EthylEster
Packaging
10mg
Price
$885
Updated
2021/12/16
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(S)-ethyl 2-(((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate Chemical Properties,Usage,Production

Uses

Sofosbuvir O-Desisopropyl O-Ethyl Ester is a useful reagent for synthesizing?β-D-2''-Deoxy-2''-α-fluoro-2''-β-C-methyluridine nucleotide that can selectively inhibit Hepatitis C virus (HCV) NS5B polymerase, which is a potential target for developing therapies for HCV.?Sofosbuvir O-Desisopropyl O-Ethyl Ester is also an impurity of Sofosbuvir (P839640).

(S)-ethyl 2-(((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate Preparation Products And Raw materials

Raw materials

Preparation Products

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(S)-ethyl 2-(((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate Suppliers

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1064684-30-5, (S)-ethyl 2-(((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoateRelated Search:

Sofosbuvir metabolites Sofosbuvir IMpurity C (2R)-2-Deoxy-2-fluoro-2-Methyl-D-erythro-pentonic acid-g-lactone 3,5-bis(4-chlorobenzoate) ((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate Phenol, 2,3,4,5-tetrafluoro- Phenol, 2,3,4,6-tetrafluoro- TRIS(PHENYL,METHYLPHENYL,ETHYLPHENYLANDNONYLPHENYL)PHOSPHATE SofosBuvir Impurity 53 L-Alanine, N-[(S)-hydroxyphenoxyphosphinyl]-, 1-Methylethyl ester, (P→3'),(P'→5')-diester with (2'R)-2'-deoxy-2'-fluoro-2'-Methyluridine diisopropylphenylphosphate Sofosbuvir Impurity 104 PSI 7411 Sofosbuvir IMpurity Sofosbuvir Impurity 108 D-Ribonic acid, 2-C-methyl-, γ-lactone, 3,5-dibenzoate Sofosbuvir IMpurity B PSI-7976 ((2R,3S,4S)-3-(benzoyloxy)-4-fluoro-4-Methyl-5-oxotetrahydrofuran-2-yl)Methyl benzoate

  • (S)-ethyl 2-(((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate
  • (S)-2-{[(2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-ylmethoxy](phenoxy)phosphorylamino}propionicacidethylester
  • Sofosbuvir ethyl ester impuriy
  • sofosbuvir Ethyl ester imp
  • Ethyl sofosbuvirQ: What is Ethyl sofosbuvir Q: What is the CAS Number of Ethyl sofosbuvir Q: What is the storage condition of Ethyl sofosbuvir Q: What are the applications of Ethyl sofosbuvir
  • L-Alanine, N-[(2'R)-2'-deoxy-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-, ethyl ester
  • Modafinil Impurity 13
  • 1064684-30-5