ChemicalBook > CAS DataBase List > UK-371804
UK-371804
- Product Name
- UK-371804
- CAS No.
- 256477-09-5
- Chemical Name
- UK-371804
- Synonyms
- UK-371804;Urokinase inhitibor 1;Urokinase inhibitor 1;UK-371804 (Urokinase inhitibor 1);UK 371804,UK-371804,Inhibitor,PAI-1,inhibit,Plasminogen activator inhibitor-1;2-(1-carbamimidamido-4-chloroisoquinoline-7-sulfonamido)-2-methylpropanoic acid;N-[[1-[(Aminoiminomethyl)amino]-4-chloro-7-isoquinolinyl]sulfonyl]-2-methylalanine;Alanine, N-[[1-[(aminoiminomethyl)amino]-4-chloro-7-isoquinolinyl]sulfonyl]-2-methyl-
- CBNumber
- CB13160423
- Molecular Formula
- C14H16ClN5O4S
- Formula Weight
- 385.83
- MOL File
- 256477-09-5.mol
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UK-371804 Property
- storage temp.
- Store at -20°C
- solubility
- DMSO:5.0(Max Conc. mg/mL);2.59(Max Conc. mM)
- form
- A crystalline solid
- color
- White to off-white
- CAS DataBase Reference
- 256477-09-5
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 27225
- Product name
- UK 371804
- Packaging
- 5mg
- Price
- $97
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 27225
- Product name
- UK 371804
- Packaging
- 25mg
- Price
- $410
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 27225
- Product name
- UK 371804
- Packaging
- 10mg
- Price
- $184
- Updated
- 2024/03/01
ChemScene
- Product number
- CS-6457
- Product name
- UK-371804
- Purity
- >98.0%
- Packaging
- 5mg
- Price
- $144
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-6457
- Product name
- UK-371804
- Purity
- >98.0%
- Packaging
- 50mg
- Price
- $780
- Updated
- 2021/12/16
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UK-371804 Chemical Properties,Usage,Production
Description
UK-371804 is a potent and selectiveurokinase-type plasmogen activator (uPA)inhibitor. It has excellent selectivityover tPA, plasmin, Factor IXa and Xa.In vitro, it is able to inhibit exogenous uPA in human chronic wound fluid (IC50=0.89 microM). In vivo, in a porcine acute excisional wound modelfollowing topical delivery, it is able to penetrate into pig wounds and inhibit exogenous uPA activity with no adverse effect on wound healing parameters. It has the potential for the treatment of chronic dermal ulcers.
References
http://www.dcchemicals.com/product_show-UK_371804.html
http://adisinsight.springer.com/drugs/800026963
Fish, P. V., et al. "Selective urokinase-type plasminogen activator inhibitors. 4. 1-(7-sulfonamidoisoquinolinyl)guanidines. "Journal of Medicinal Chemistry 50.10(2007):2341.
UK-371804 Preparation Products And Raw materials
Raw materials
Preparation Products
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UK-371804 Suppliers
- Tel
- 021-52996696，15000506266 15000506266
- Fax
- +86-21-52996696
- Country
- China
- ProdList
- 4575
- Advantage
- 55
- Tel
- 021-61350663 13052117465
- Fax
- 021-61350662
- sales@zehanbiopharma.com
- Country
- China
- ProdList
- 1004
- Advantage
- 55
- Tel
- 15076683720
- Fax
- 022-23754520
- klq@cw-bio.com
- Country
- China
- ProdList
- 5931
- Advantage
- 55
- Tel
- 177-54423994 17754423994
- Fax
- QQ:2853530913
- 2853530910@QQ.com
- Country
- China
- ProdList
- 8011
- Advantage
- 62
- Tel
- 21-31433387 15618786686
- Fax
- QQ:1369748377
- sales@rechemscience.com
- Country
- China
- ProdList
- 2986
- Advantage
- 58
- Tel
- 021-QQ：65489617 15618227136
- Fax
- 21-5161 9052
- Sales@ATKchemical.com
- Country
- China
- ProdList
- 7295
- Advantage
- 58
- Tel
- 021-2022843681 15618226720
- Fax
- +86-21-51601218
- lucy@atkchemical.com
- Country
- China
- ProdList
- 9952
- Advantage
- 58
- Tel
- 010-60605840 18892239720
- Fax
- 010-60605840
- psaitong@jm-bio.com
- Country
- China
- ProdList
- 12306
- Advantage
- 58
- Tel
- 0519-83246372 13585352506
- Fax
- 0519-83246372
- Country
- China
- ProdList
- 1844
- Advantage
- 58
- Tel
- 0550-5196001 15000891977
- Fax
- 0550-5196001
- wj520wjxby@126.com
- Country
- China
- ProdList
- 1925
- Advantage
- 55
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View Lastest Price from UK-371804 manufacturers
Career Henan Chemical Co
- Product
- UK-371804 256477-09-5
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99.99%
- Supply Ability
- 200kg
- Release date
- 2019-12-20