Description References
ChemicalBook > CAS DataBase List > Diclazuril

Diclazuril

Description References
Product Name
Diclazuril
CAS No.
101831-37-2
Chemical Name
Diclazuril
Synonyms
Qiujia;Nuoqiu;Vecoxan;R-64433;CLINACOX;clinazox;iclazuril;DICLAZUTIL;DICLAZURIL;To g beads
CBNumber
CB1317293
Molecular Formula
C17H9Cl3N4O2
Formula Weight
407.64
MOL File
101831-37-2.mol
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Diclazuril Property

Melting point:
290.5°
Density 
1.56±0.1 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
DMF: 5mg/mL; DMSO: 5mg/mL; DMSO:PBS (pH 7.2) (1:5): 0.16mg/mL
pka
5.89±0.20(Predicted)
form 
Solid
color 
White to Light yellow to Light orange
Merck 
14,3080
InChI
InChI=1S/C17H9Cl3N4O2/c18-10-3-1-9(2-4-10)12(7-21)16-13(19)5-11(6-14(16)20)24-17(26)23-15(25)8-22-24/h1-6,8,12H,(H,23,25,26)
InChIKey
ZSZFUDFOPOMEET-UHFFFAOYSA-N
SMILES
C1(C=C(C(C(C#N)C2=CC=C(Cl)C=C2)=C(Cl)C=1)Cl)N1N=CC(=O)NC1=O
LogP
2.439 (est)
CAS DataBase Reference
101831-37-2(CAS DataBase Reference)
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Safety

Safety Statements 
24/25
WGK Germany 
2
RTECS 
CY1697600
HS Code 
29336990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
34057
Product name
Diclazuril
Purity
VETRANAL?, analytical standard
Packaging
100mg
Price
$113
Updated
2024/03/01
Sigma-Aldrich
Product number
1188560
Product name
Diclazuril
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
200mg
Price
$436
Updated
2024/03/01
TCI Chemical
Product number
D5457
Product name
Diclazuril
Purity
>98.0%(HPLC)(T)
Packaging
1g
Price
$53
Updated
2024/03/01
TCI Chemical
Product number
D5457
Product name
Diclazuril
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$262
Updated
2024/03/01
Cayman Chemical
Product number
27047
Product name
Diclazuril
Packaging
5g
Price
$68
Updated
2024/03/01
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Diclazuril Chemical Properties,Usage,Production

Description

Diclazuril (molecular formula: C17H9Cl3N4O2, Trade name: Vecoxan) belongs to a kind of coccidiostat and potent antiprotozoal agents. It is mainly used for the treatment, control, prevention and improvements of Coccidal infections. It alleviates the symptoms of the patients by interrupting the life cycle of the parasites. It induces the morphological changes and attenuates the mitochondrial transmembrane potential in meroites. It can prevent congenital toxoplasmosis and have anticoccidial effects in vivo. It is active through oral administration.  

References

http://www.tabletwise.com/medicine/diclazuril
https://en.wikipedia.org/wiki/Diclazuril
http://www.abcam.com/diclazuril-ab143604.html

Chemical Properties

Light yellow or off-white powder, almost insoluble in water, slightly soluble in ethanol, ether, soluble in N,N-2 methylformamide (DMF), dimethylsulfone (DMSO), tetrahydrofuran (THF).

Uses

Diclazuril is a triazinone antiprotozoal that Nucleotide analog with broad-spectrum anticoccidial activity. It has a control effect on a variety of coccidiosis, and is used to prevent coccidiosis in chickens, ducks, quails, turkeys, geese and rabbits.

Definition

ChEBI: 2-(4-chlorophenyl)-2-[2,6-dichloro-4-(3,5-dioxo-1,2,4-triazin-2-yl)phenyl]acetonitrile is a nitrile.

Application

Diclazuril is a less toxic, orally administered triazine antiprotozoal. It is widely used in veterinary medicine as a feed additive and veterinary drug. It is registered for oral use in broilers and lambs. Its use in cats (one dose of 25 mg/kg BW) is off-label only. It may be used clinically for the treatment of bovine protozoa. It is also used for the treatment of equine protozoan spinal cord encephalitis (EPM) caused by neuronal sarcocysts.

Veterinary Drugs and Treatments

Diclazuril is a coccidiostat. It is indicated for the treatment of equine protozoal myeloencephalitis (EPM) caused by Sarcocystis neurona and as a coccidiostat in broiler chickens. Diclazuril could potentially be useful in treating coccidiosis, Neospora caninum and Toxoplasma infections in dogs or cats.

Diclazuril Preparation Products And Raw materials

Raw materials

Preparation Products

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Diclazuril Suppliers

Dr. Ehrenstorfer GmbH
Tel
--
Fax
--
Email
info@analytical-standards.com
Country
Germany
ProdList
5545
Advantage
66
Service Chemical Inc.
Tel
--
Fax
--
Email
sales@chemos-group.com
Country
Germany
ProdList
6350
Advantage
71
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View Lastest Price from Diclazuril manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd
Product
Diclazuril 101831-37-2
Price
US $150.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
500kg
Release date
2024-11-22
Henan Suikang Pharmaceutical Co.,Ltd.
Product
Diclazuril 101831-37-2
Price
US $0.00/kg
Min. Order
5kg
Purity
≥96.0%
Supply Ability
1tons
Release date
2024-04-26
HebeiShuoshengImportandExportco.,Ltd
Product
Diclazuril 101831-37-2
Price
US $6.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000KG/Month
Release date
2024-08-02

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