ChemicalBook > CAS DataBase List > 4-Fluorophthalic acid

4-Fluorophthalic acid

Product Name: 4-Fluorophthalic acid
CAS No.: 320-97-8
Chemical Name: 4-Fluorophthalic acid
Synonyms: RARECHEM AL BO 0829;4-fluorophthalicaci;4-FLUOROPHTHALIC ACID;4-fluorobenzene-1,2-dioic acid;320-97-8;4-Fluorobenzene-1,2-dicarboxylic acid;1,2-Benzenedicarboxylic acid, 4-fluoro-
CBNumber: CB1317369
Molecular Formula: C8H5FO4
Formula Weight: 184.12
MOL File: 320-97-8.mol

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4-Fluorophthalic acid Property

Melting point:: 154-158℃
Boiling point:: 377.2±27.0 °C(Predicted)
Density: 1.551±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: DMSO (Slightly), Methanol (Slightly)
pka: 2.91±0.10(Predicted)
form: Solid
color: White to Off-White
Water Solubility: Insoluble in water.
Stability:: Hygroscopic
InChI: InChI=1S/C8H5FO4/c9-4-1-2-5(7(10)11)6(3-4)8(12)13/h1-3H,(H,10,11)(H,12,13)
InChIKey: OMCXTFVBNCFZMY-UHFFFAOYSA-N
SMILES: C1(C(O)=O)=CC=C(F)C=C1C(O)=O
CAS DataBase Reference: 320-97-8(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-37
Hazard Note: Irritant
HS Code: 29173990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: F621483
Product name: 4-FluorophthalicAcid
Packaging: 100mg
Price: $60
Updated: 2021/12/16

TRC

Product number: F621483
Product name: 4-FluorophthalicAcid
Packaging: 500mg
Price: $75
Updated: 2021/12/16

SynQuest Laboratories

Product number: 2621-3-14
Product name: 4-Fluorophthalic acid
Purity: 97%
Packaging: 1g
Price: $20
Updated: 2021/12/16

AK Scientific

Product number: X4506
Product name: 4-Fluorophthalicacid
Packaging: 1g
Price: $49
Updated: 2021/12/16

SynQuest Laboratories

Product number: 2621-3-14
Product name: 4-Fluorophthalic acid
Purity: 97%
Packaging: 5G
Price: $75
Updated: 2021/12/16

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4-Fluorophthalic acid Chemical Properties,Usage,Production

Uses

4-Fluorophthalic acid is used as a pharmaceutical intermediate.

Synthesis

452-64-2

320-97-8

Preparation of B: 4-fluoro-1,2-dimethylbenzene A (50.0 g, 402.7 mmol) was dissolved in 150 mL of water/tert-butanol (70/30, v/v) mixed solvent with an excess of KMnO4 (400 g, 2.54 mol). After the reaction mixture was refluxed overnight, EtOH (900 mL) was added to quench the unreacted KMnO4, followed by distillation to remove the alcohol. The resulting brown suspension was filtered through a diatomaceous earth pad and the filtrate was concentrated and acidified with concentrated HCl. The product was collected by filtration, the aqueous phase was extracted with EtOAc and the organic phase was dried with Na2SO4. After evaporation of the solvent under reduced pressure, a white solid B (70.0 g, 94% yield) was obtained.1H-NMR (400 MHz, DMSO-d6): δ 7.39 (m, 1H), 7.63 (br s, 1H), 7.99 (br s, 1H).

References

[1] Patent: WO2008/151211, 2008, A1. Location in patent: Page/Page column 54
[2] Australian Journal of Chemistry, 1976, vol. 29, p. 2571 - 2581

4-Fluorophthalic acid Preparation Products And Raw materials

Raw materials

Preparation Products

Sulindac

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View Lastest Price from 4-Fluorophthalic acid manufacturers

Hefei Lbao Physical & Chemical Science Co.,Ltd

Product: 4-fluorophthalic acid 320-97-8
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: Customise
Release date: 2025-08-19

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: 4-Fluorophthalic acid 320-97-8
Price: US $2.20-8.80/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2025-06-17

Hebei Chuanghai Biotechnology Co., Ltd

Product: 4-Fluorophthalic acid 320-97-8
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20 mt
Release date: 2024-12-04

320-97-8, 4-Fluorophthalic acidRelated Search:

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RARECHEM AL BO 0829

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320-97-8

C8H5FO4