MELOXICAM-D3

Product Name: MELOXICAM-D3
CAS No.: 942047-63-4
Chemical Name: MELOXICAM-D3
Synonyms: Mobic-d3;Metacam-d3;Parocin-d3;Movatec-d3;Movalis-d3;Mobicox-d3;MELOXICAM-D3;Meloxicam D4;[2H3]-Meloxicam;Meloxicam-d3
CBNumber: CB1327322
Molecular Formula: C14H13N3O4S2
Formula Weight: 351.4
MOL File: Mol file

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MELOXICAM-D3 Property

Melting point:: 249-251°C
storage temp.: -20°C Freezer
solubility: DMF: 20 mg/ml; DMSO: 20 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml
form: Solid
color: Light yellow to yellow
CAS DataBase Reference: 942047-63-4

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Safety

Hazard Codes: Xn
Risk Statements: 22
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 34109
Product name: Meloxicam-d3
Purity: VETRANAL?, analytical standard
Packaging: 50mg
Price: $856
Updated: 2022/05/15

Cayman Chemical

Product number: 25508
Product name: Meloxicam-d3
Purity: ≥99% deuterated forms (d1-d3)
Packaging: 500μg
Price: $175
Updated: 2024/03/01

Cayman Chemical

Product number: 25508
Product name: Meloxicam-d3
Purity: ≥99% deuterated forms (d1-d3)
Packaging: 1mg
Price: $330
Updated: 2024/03/01

TRC

Product number: M216102
Product name: Meloxicam-d3
Packaging: 1mg
Price: $175
Updated: 2021/12/16

ChemScene

Product number: CS-0111539
Product name: MeloxicamD4
Packaging: 1mg
Price: $230
Updated: 2021/12/16

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MELOXICAM-D3 Chemical Properties,Usage,Production

Description

Meloxicam-d3 is intended for use as an internal standard for the quantification of meloxicam by GC- or LC-MS. Meloxicam is a selective inhibitor of COX-2 (IC50s = 11.8 and 143 μM for COX-2 and COX-1, respectively, in an enzyme activity assay) and a non-steroidal anti-inflammatory drug (NSAID). Meloxicam (0.03%) reduces croton oil-induced increases in TNF-α and IL-1β mRNA levels and increases IL-10 mRNA levels in cornea in a rabbit model of acute ocular inflammation. It inhibits pleural plasma exudation in a carrageenan-induced rat model of pleurisy when administered at a dose of 3 mg/kg.In a canine model of unilateral osteoarthritis of the right stifle joint, meloxicam reduces prostaglandin E2 (PGE2) levels in plasma and right stifle joint synovial fluid when administered at a dose of 0.2 mg/kg. Formulations containing meloxicam have been used in the treatment of osteoarthritis and rheumatoid arthritis.

Chemical Properties

Yellow Solid

Uses

MELOXICAM-D3 is a preferential cyclooxygenase (COX-2) inhibitor,it is used as an anti-inflammatory.

References

1. Ogino, K., Hatanaka, K., Kawamura, M., et al. Evaluation of pharmacological profile of meloxicam as an anti-inflammatory agent, with particular reference to its relative selectivity for cyclooxygenase-2 over cyclooxygenase-1. Pharmacology 55, 44-53 (1997).
2. Cruz, R., Quintana-Hau, J.D., González, J.R., et al. Effects of an ophthalmic formulation of meloxicam on COX-2 expression, PGE2 release, and cytokine expression in a model of acute ocular inflammation. Br. J. Ophthalmol. 92, 120-125 (2008).
3. Jones, C.J., Streppa, H.K., Harmon, B.G., et al. In vivo effects of meloxicam and aspirin on blood, gasteric mucosal, and synovial fluid prosanoid synthesis in dogs. Am. J. Vet. Res. 63, 1527-1531 (2002).

MELOXICAM-D3 Preparation Products And Raw materials

Raw materials

Preparation Products

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MELOXICAM-D3 Suppliers

Canada 2 China 36 France 1 India 5 Switzerland 1 United States 6 Global 51

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

Clearsynth Labs Limited

Tel: +91-22-26355700
Fax: +91-22-26355701
Email: info@clearsynth.com
Country: India
ProdList: 9679
Advantage: 58

Cato Research Chemicals Inc.

Tel: 020-81960175
Fax: +1-541-2553641
Email: min.he@cato-chem.com
Country: China
ProdList: 1955
Advantage: 55

Alta Scientific Co., Ltd.

Tel: 022-6537-8550 15522853686
Fax: 022-2532-9655
Email: sales@altasci.com.cn
Country: China
ProdList: 4511
Advantage: 55

Artis Biotech Co. Ltd.

Tel: 0575-18780151478 18582380095
Fax: 0575-89298961
Email: sales@artisbio.com
Country: China
ProdList: 2964
Advantage: 58

Chengdu Novel Biomedical Co., Ltd.

Tel: 028-85255396 18302801538
Fax: 028-85255396
Email: cdnovell@163.com
Country: China
ProdList: 2310
Advantage: 58

Shanghai Han-Xiang Chemical Co., Ltd.

Tel: 15971444841
Fax: 18327183813
Email: amber@biochempartner.com
Country: China
ProdList: 3061
Advantage: 58

Shanghai Hongye Biotechnology Co. Ltd

Tel: 400-9205774
Email: sales@glpbio.cn
Country: China
ProdList: 6777
Advantage: 58

Hefei Molake Biotechnology Co., Ltd.

Tel: 0551-66336380 18956014586
Fax: 055166336380
Email: 983438788@qq.com
Country: China
ProdList: 2123
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32080
Advantage: 58

942047-63-4, MELOXICAM-D3Related Search:

IODOMETHANE-D3 Meloxicam

4-HYDROXY-2-(METHYL-D3)-1,1-DIOXO-BENZO[E]-1,2-THIAZINE-3-CARBOXYLIC ACID (5-METHYL-2-THIAZOLYL)AMIDE

MELOXICAM-D3

4-Hydroxy-2-(methyl-d3)-1,1-dioxo-benzo[e]-1,2-thiazine-3-carboxylic acid (5-methyl-2-thiazolyl)amide

Meloxicam-d<sub>3</sub>

4-Hydroxy-2-(methyl-d3)-N-(5-methyl-2-thiazolyl)-2H-1,2-benzothiazine-3-carboxamide 1,1,-Dioxide

Metacam-d3

Mobic-d3

Mobicox-d3

Movalis-d3

Movatec-d3

Parocin-d3

4-hydroxy-N-(5-methyl-1,3-thiazol-2-yl)-1,1-dioxo-2-(trideuteriomethyl)-1λ<sup>6</sup>,2-benzothiazine-3-carboxamide

4-hydroxy-N-(5-methyl-1,3-thiazol-2-yl)-1,1-dioxo-2-(trideuteriomethyl)-1λ^{6},2-benzothiazine-3-carboxamide

4-hydroxy-N-(5-methyl-1,3-thiazol-2-yl)-1,1-dioxo-2-(trideuteriomethyl)-1$l^{6},2-benzothiazine-3-carboxamide

[2H3]-Meloxicam

Meloxicam D4

4-hydroxy-2-(2H?)methyl-N-(5-methyl-1,3-thiazol-2-yl)-1,1-dioxo-2H-1λ?,2-benzothiazine-3-carboxamide

942047-63-4

C14H10D3N3O4S2

Isotope Labelled Compounds

Heterocycles

Intermediates & Fine Chemicals

Isotope Labeled Compounds

Pharmaceuticals

Sulfur & Selenium Compounds