ChemicalBook > CAS DataBase List > PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXYLIC ACID

PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXYLIC ACID

Product Name: PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXYLIC ACID
CAS No.: 25940-35-6
Chemical Name: PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXYLIC ACID
Synonyms: Pyrazolo[1,5-a]pyrimidin-3-carboxylic acid;Albb-005394;AKOS B001273;ART-CHEM-BB B001273;TIMTEC-BB SBB006995;3-Carboxypyrazolo[1,5-a]pyrimidine;25940-35-6;3-pyrazolo[1,5-a]pyrimidinecarboxylic acid;PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXYLIC ACID;Pyrazolo[1,5-a]pyrimidine-3-carboxylic acid(I)
CBNumber: CB1329614
Molecular Formula: C7H5N3O2
Formula Weight: 163.13
MOL File: 25940-35-6.mol

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PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXYLIC ACID Property

Melting point:: 180°C
Density: 1.58±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
pka: -1.71±0.41(Predicted)
form: solid
Appearance: Yellow to brown Solid
Water Solubility: Soluble in water
InChI: InChI=1S/C7H5N3O2/c11-7(12)5-4-9-10-3-1-2-8-6(5)10/h1-4H,(H,11,12)
InChIKey: HNYVPKNVKSTVJO-UHFFFAOYSA-N
SMILES: C12=C(C(O)=O)C=NN1C=CC=N2
CAS DataBase Reference: 25940-35-6(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 36/37/38-22
Safety Statements: 26-36
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 2916399090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 739812
Product name: Pyrazolo[1,5-a]pyrimidine-3-carboxylic acid
Purity: 95%
Packaging: 1g
Price: $181
Updated: 2025/07/31

TRC

Product number: P846508
Product name: Pyrazolo[1,5-a]pyrimidine-3-carboxylic acid
Packaging: 500mg
Price: $75
Updated: 2021/12/16

Activate Scientific

Product number: AS16024
Product name: Pyrazolo[1,5-a]pyrimidine-3-carboxylic acid
Purity: 97+%
Packaging: 1g
Price: $47
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H21-1-BW
Product name: Pyrazolo[1,5-a]pyrimidine-3-carboxylic acid
Packaging: 1g
Price: $83
Updated: 2021/12/16

Apolloscientific

Product number: OR41128
Product name: Pyrazolo[1,5-a]pyrimidine-3-carboxylic acid
Purity: 97%
Packaging: 5g
Price: $87
Updated: 2021/12/16

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PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXYLIC ACID Chemical Properties,Usage,Production

Uses

Pyrazolo[1,5-a]pyrimidine-3-carboxylic acid, is used as a chemicals, pharmaceutical intermediates, reagents. It is an important raw material and intermediate used in pharmaceuticals, agro based and dye stuff fields.

Synthesis

115932-00-8

25940-35-6

The general procedure for the synthesis of pyrazolo[1,5-a]pyrimidine-3-carboxylic acid from ethyl pyrazolo[1,5-a]pyrimidine-3-carboxylate was as follows: to a mixture of ethyl pyrazolo[1,5-a]pyrimidine-3-carboxylate (3.15 g, 16.4 mmol) in ethanol (50 mL) and water (40 mL) was added an aqueous solution of 2 M potassium hydroxide (40 mL). The reaction mixture was stirred at 50 °C for 2 h, subsequently cooled to room temperature and concentrated under vacuum. The resulting mixture was adjusted to pH=2 with 1 M aqueous hydrochloric acid, at which time a white solid precipitated. The white solid product was collected by filtration to give 2.6 g (97% yield). The product was detected by LC-MS (ESI, negative ion mode), m/z: 162.1 [M-H]-. 1H NMR (600 MHz, DMSO-d6) δ (ppm): 9.26 (dd, J=7.0,1.7 Hz, 1H), 8.80 (dd, J=4.1,1.7 Hz, 1H), 8.58 (s, 1H), 7.26 ( dd, J=7.0,4.1 Hz, 1H).

References

[1] Patent: WO2015/73267, 2015, A1. Location in patent: Paragraph 390
[2] Patent: CN104650092, 2017, B. Location in patent: Paragraph 0770-0771; 0776-0777

PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXYLIC ACID manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: Pyrazolo[1,5-a]pyrimidine-3-carboxylic acid 25940-35-6
Price: US $1.60-6.60/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2025-06-19

Dideu Industries Group Limited

Product: PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXYLIC ACID 25940-35-6
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons
Release date: 2022-02-17

Zhuozhou Wenxi import and Export Co., Ltd

Product: PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXYLIC ACID 25940-35-6
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-08-11

25940-35-6, PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXYLIC ACIDRelated Search:

PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBONITRILE PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBALDEHYDE PYRAZOLO[1,5-A]PYRIDINE-7-CARBALDEHYDE PYRAZOLO[1,5-A]PYRIDINE-7-CARBOXALDEHYDE PYRAZOLO[1,5-A]PYRIMIDINE-5,7(4H,6H)-DIONE Pyrazolo[1,5-a]pyriMidin-7-ol Pyrazolo[1,5-a]pyridine-3-carbonitrile 3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRAZOLO[1,5-A]PYRIDINE METHYL PYRAZOLO[1,5-A]PYRIDINE-3-CARBOXYLATE Pyrazolo[1,5-a]pyridine-4-carboxylic acid pyrazolo[1,5-a]pyridine-5-carboxylic acid Pyrazolo[1,5-a]pyridine-7-carbonitrile Pyrazolo[1,5-a]pyridine-7-carboxylic acid amide Pyrazolo[1,5-a]pyrimidine-3-boronic acid pinacol ester PYRAZOLO[1,5-A]PYRIDINE-7-CARBOXYLIC ACID PYRAZOLO[1,5-A]PYRIDINE-3-CARBOXYLIC ACID HYDRAZIDE Pyrazolo1,5-apyridine-5-boronic acid picol ester Pyrazolo[1,5-a]pyrimidine-2-carboxylic acid (9CI)

ART-CHEM-BB B001273

Pyrazolo[1,5-a]pyrimidin-3-carboxylic acid

Pyrazolo[1,5-A]Pyrimidine-3-Carboxylic Acid(WX614223)

AKOS B001273

TIMTEC-BB SBB006995

PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXYLIC ACID

Pyrazolo[1,5-a]pyrimidine-3-carboxylic acid(I)

Albb-005394

pyrazolo[1,5-a]pyrimidine-3-carboxylic acid(SALTDATA: FREE)

3-Carboxypyrazolo[1,5-a]pyrimidine

3-pyrazolo[1,5-a]pyrimidinecarboxylic acid

Pyrazolo[1,5-a]pyrimidine-3-carboxylic acid 97%

PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXYLIC ACID ISO 9001：2015 REACH

Pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (8CI, 9CI, ACI)

Pyrazole [1-5, A] pyrimidine-3-carboxylic acid

Pyrazolo[1,5-<i>a</i>]pyrimidine-3-carboxylic acid

25940-35-6

29540-35-6