PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXYLIC ACID
- Product Name
- PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXYLIC ACID
- CAS No.
- 25940-35-6
- Chemical Name
- PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXYLIC ACID
- Synonyms
- Pyrazolo[1,5-a]pyrimidin-3-carboxylic acid;Albb-005394;AKOS B001273;ART-CHEM-BB B001273;TIMTEC-BB SBB006995;3-Carboxypyrazolo[1,5-a]pyrimidine;25940-35-6;3-pyrazolo[1,5-a]pyrimidinecarboxylic acid;PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXYLIC ACID;Pyrazolo[1,5-a]pyrimidine-3-carboxylic acid(I)
- CBNumber
- CB1329614
- Molecular Formula
- C7H5N3O2
- Formula Weight
- 163.13
- MOL File
- 25940-35-6.mol
PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXYLIC ACID Property
- Melting point:
- 180°C
- Density
- 1.58±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- -1.71±0.41(Predicted)
- form
- solid
- Appearance
- Yellow to brown Solid
- Water Solubility
- Soluble in water
- InChI
- InChI=1S/C7H5N3O2/c11-7(12)5-4-9-10-3-1-2-8-6(5)10/h1-4H,(H,11,12)
- InChIKey
- HNYVPKNVKSTVJO-UHFFFAOYSA-N
- SMILES
- C12=C(C(O)=O)C=NN1C=CC=N2
- CAS DataBase Reference
- 25940-35-6(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-22
- Safety Statements
- 26-36
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 2916399090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 739812
- Product name
- Pyrazolo[1,5-a]pyrimidine-3-carboxylic acid
- Purity
- 95%
- Packaging
- 1g
- Price
- $181
- Updated
- 2025/07/31
- Product number
- P846508
- Product name
- Pyrazolo[1,5-a]pyrimidine-3-carboxylic acid
- Packaging
- 500mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- AS16024
- Product name
- Pyrazolo[1,5-a]pyrimidine-3-carboxylic acid
- Purity
- 97+%
- Packaging
- 1g
- Price
- $47
- Updated
- 2021/12/16
- Product number
- 4H21-1-BW
- Product name
- Pyrazolo[1,5-a]pyrimidine-3-carboxylic acid
- Packaging
- 1g
- Price
- $83
- Updated
- 2021/12/16
- Product number
- OR41128
- Product name
- Pyrazolo[1,5-a]pyrimidine-3-carboxylic acid
- Purity
- 97%
- Packaging
- 5g
- Price
- $87
- Updated
- 2021/12/16
PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXYLIC ACID Chemical Properties,Usage,Production
Uses
Pyrazolo[1,5-a]pyrimidine-3-carboxylic acid, is used as a chemicals, pharmaceutical intermediates, reagents. It is an important raw material and intermediate used in pharmaceuticals, agro based and dye stuff fields.
Synthesis
115932-00-8
25940-35-6
The general procedure for the synthesis of pyrazolo[1,5-a]pyrimidine-3-carboxylic acid from ethyl pyrazolo[1,5-a]pyrimidine-3-carboxylate was as follows: to a mixture of ethyl pyrazolo[1,5-a]pyrimidine-3-carboxylate (3.15 g, 16.4 mmol) in ethanol (50 mL) and water (40 mL) was added an aqueous solution of 2 M potassium hydroxide (40 mL). The reaction mixture was stirred at 50 °C for 2 h, subsequently cooled to room temperature and concentrated under vacuum. The resulting mixture was adjusted to pH=2 with 1 M aqueous hydrochloric acid, at which time a white solid precipitated. The white solid product was collected by filtration to give 2.6 g (97% yield). The product was detected by LC-MS (ESI, negative ion mode), m/z: 162.1 [M-H]-. 1H NMR (600 MHz, DMSO-d6) δ (ppm): 9.26 (dd, J=7.0,1.7 Hz, 1H), 8.80 (dd, J=4.1,1.7 Hz, 1H), 8.58 (s, 1H), 7.26 ( dd, J=7.0,4.1 Hz, 1H).
References
[1] Patent: WO2015/73267, 2015, A1. Location in patent: Paragraph 390
[2] Patent: CN104650092, 2017, B. Location in patent: Paragraph 0770-0771; 0776-0777
PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXYLIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXYLIC ACID Suppliers
- Tel
- --
- Fax
- --
- info@abcr.de
- Country
- Germany
- ProdList
- 6831
- Advantage
- 75
- Tel
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- Fax
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- akos@akosgmbh.de
- Country
- Germany
- ProdList
- 6717
- Advantage
- 72
- Tel
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- Fax
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- contact@chemcollect.de
- Country
- Germany
- ProdList
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- Advantage
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View Lastest Price from PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXYLIC ACID manufacturers
- Product
- Pyrazolo[1,5-a]pyrimidine-3-carboxylic acid 25940-35-6
- Price
- US $1.60-6.60/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2025-06-19
- Product
- PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXYLIC ACID 25940-35-6
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons
- Release date
- 2022-02-17
- Product
- PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXYLIC ACID 25940-35-6
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11