ARS-1620

ChemicalBook > CAS DataBase List > ARS-1620

Product Name: ARS-1620
CAS No.: 1698055-85-4
Chemical Name: ARS-1620
Synonyms: CPD1588;ARS-1620;ARS-1620;ARS 1620;ARS1620;inhibit,Ras,Inhibitor,ARS-1620,ARS 1620,ARS1620;(S)-1-(4-(6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl)piperazin-1-yl)prop-2-en-1-one;(S)-1-[4-[6-Chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)-4-quinazolinyl]-1-piperazinyl]-2-propen-1-one;2-Propen-1-one, 1-[4-[(7S)-6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)-4-quinazolinyl]-1-piperazinyl]-;1-?[4-?[(7S)?-?6-?Chloro-?8-?fluoro-?7-?(2-?fluoro-?6-?hydroxyphenyl)?-?4-?quinazolinyl]?-?1-?piperazinyl]?-?2-?propen-?1-?one
CBNumber: CB13369787
Molecular Formula: C21H17ClF2N4O2
Formula Weight: 430.84
MOL File: 1698055-85-4.mol

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ARS-1620 Property

Boiling point:: 614.7±55.0 °C(Predicted)
Density: 1.434±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO:70.0(Max Conc. mg/mL);162.47(Max Conc. mM)
form: A solid
pka: 6.03±0.35(Predicted)
color: Off-white to light yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 27915
Product name: ARS1620
Packaging: 1mg
Price: $118
Updated: 2024/03/01

Cayman Chemical

Product number: 27915
Product name: ARS1620
Packaging: 5mg
Price: $351
Updated: 2024/03/01

ChemScene

Product number: CS-0035119
Product name: ARS-1620
Purity: 99.20%
Packaging: 25mg
Price: $690
Updated: 2021/12/16

ChemScene

Product number: CS-0035119
Product name: ARS-1620
Purity: 99.20%
Packaging: 50mg
Price: $990
Updated: 2021/12/16

ChemScene

Product number: CS-0035119
Product name: ARS-1620
Purity: 99.20%
Packaging: 100mg
Price: $1250
Updated: 2021/12/16

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ARS-1620 Chemical Properties,Usage,Production

Uses

ARS-1620, is an atropisomeric selective KRASG12C inhibitor with desirable pharmacokinetics.

Definition

ChEBI: ARS-1620 is a qinazoline derivative carrying chloro and fluoro substituents at positions 6 and 8 respectively, a 2-fluoro-6-hydroxyphenyl group at position 7, and a 4-(prop-2-enoyl)piperazin-1-yl group at position 4. A potent, selective, and orally bioavailable covalent KRAS-G12C inhibitor, it inhibits the protein coding gene KRAS (Kirsten rat sarcoma virus) with high potency in cells and animals. It has a role as an inhibitor, an antiviral agent and an antineoplastic agent.

ARS-1620 Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from ARS-1620 manufacturers

Career Henan Chemical Co

Product: ARS-1620 1698055-85-4
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 100kg
Release date: 2020-01-18

1698055-85-4, ARS-1620Related Search:

Sotorasib CPI-444 Bardoxolone methyl

ARS-1620

CPD1588

ARS-1620;ARS 1620;ARS1620

(S)-1-(4-(6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl)piperazin-1-yl)prop-2-en-1-one

1-?[4-?[(7S)?-?6-?Chloro-?8-?fluoro-?7-?(2-?fluoro-?6-?hydroxyphenyl)?-?4-?quinazolinyl]?-?1-?piperazinyl]?-?2-?propen-?1-?one

2-Propen-1-one, 1-[4-[(7S)-6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)-4-quinazolinyl]-1-piperazinyl]-

(S)-1-[4-[6-Chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)-4-quinazolinyl]-1-piperazinyl]-2-propen-1-one

inhibit,Ras,Inhibitor,ARS-1620,ARS 1620,ARS1620

1698055-85-4

C21H17ClF2N4O2

APIs

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