ChemicalBook > CAS DataBase List > ARS-1630

ARS-1630

Product Name
ARS-1630
CAS No.
1698055-86-5
Chemical Name
ARS-1630
Synonyms
CPD2016;ARS-1630;ARS-1630;ARS 1630;ARS1630;inhibit,Ras,ARS-1630,ARS1630,Inhibitor,ARS 1630;1-{4-[6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl]piperazin-1-yl}prop-2-en-1-one;(R)-1-(4-(6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl)piperazin-1-yl)prop-2-en-1-one;2-Propen-1-one, 1-[4-[(7R)-6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)-4-quinazolinyl]-1-piperazinyl]-
CBNumber
CB13386449
Molecular Formula
C21H17ClF2N4O2
Formula Weight
430.84
MOL File
1698055-86-5.mol
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ARS-1630 Property

Boiling point:
614.7±55.0 °C(Predicted)
Density 
1.434±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO : ≥ 69 mg/mL (160.15 mM)
form 
Solid
pka
6.03±0.35(Predicted)
color 
White to yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0035117
Product name
ARS-1630
Purity
98.01%
Packaging
5mg
Price
$250
Updated
2021/12/16
ChemScene
Product number
CS-0035117
Product name
ARS-1630
Purity
98.01%
Packaging
10mg
Price
$350
Updated
2021/12/16
ChemScene
Product number
CS-0035117
Product name
ARS-1630
Purity
98.01%
Packaging
25mg
Price
$690
Updated
2021/12/16
ChemScene
Product number
CS-0035117
Product name
ARS-1630
Purity
98.01%
Packaging
50mg
Price
$990
Updated
2021/12/16
ChemScene
Product number
CS-0035117
Product name
ARS-1630
Purity
98.01%
Packaging
100mg
Price
$1300
Updated
2021/12/16
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ARS-1630 Chemical Properties,Usage,Production

Definition

ChEBI: ARS-1620 is a qinazoline derivative carrying chloro and fluoro substituents at positions 6 and 8 respectively, a 2-fluoro-6-hydroxyphenyl group at position 7, and a 4-(prop-2-enoyl)piperazin-1-yl group at position 4. A potent, selective, and orally bioavailable covalent KRAS-G12C inhibitor, it inhibits the protein coding gene KRAS (Kirsten rat sarcoma virus) with high potency in cells and animals. It has a role as an inhibitor, an antiviral agent and an antineoplastic agent.

ARS-1630 Preparation Products And Raw materials

Raw materials

Preparation Products

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ARS-1630 Suppliers

Shanghai Mawei Biological Technology Co., LTD
Tel
13671830408
Email
maievbiotech@163.com
Country
China
ProdList
257
Advantage
58
ShangHai Caerulum Pharma Discovery Co., Ltd.
Tel
18149758185 18149758185
Email
sales-cpd@caerulumpharma.com
Country
China
ProdList
3466
Advantage
58
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696,15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4566
Advantage
55
ATK CHEMICAL COMPANY LIMITED
Tel
021-51619050 13301662590
Fax
+86-21-51619052
Email
mandy@atkchemical.com
Country
China
ProdList
10199
Advantage
55
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Shanghai Biopharmaleader Co., Ltd.
Tel
+86 18721201413
Fax
+86 (21) 5775-8967
Email
sales@biopharmaleader.com
Country
China
ProdList
1720
Advantage
58
Fan De(Beijing) Biotechnology Co., Ltd.
Tel
15911056312
Email
liming@bio-fount.com
Country
China
ProdList
9729
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6391
Advantage
58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Tel
86-571-88216897,88216896 13588875226
Fax
86-571-88216895
Email
sales@hzclap.com
Country
CHINA
ProdList
6312
Advantage
58

1698055-86-5, ARS-1630Related Search:


  • ARS-1630
  • CPD2016
  • ARS-1630;ARS 1630;ARS1630
  • (R)-1-(4-(6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl)piperazin-1-yl)prop-2-en-1-one
  • 2-Propen-1-one, 1-[4-[(7R)-6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)-4-quinazolinyl]-1-piperazinyl]-
  • inhibit,Ras,ARS-1630,ARS1630,Inhibitor,ARS 1630
  • 1-{4-[6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl]piperazin-1-yl}prop-2-en-1-one
  • 1698055-86-5