ARS-1630
- Product Name
- ARS-1630
- CAS No.
- 1698055-86-5
- Chemical Name
- ARS-1630
- Synonyms
- CPD2016;ARS-1630;ARS-1630;ARS 1630;ARS1630;inhibit,Ras,ARS-1630,ARS1630,Inhibitor,ARS 1630;(R)-1-(4-(6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl)piperazin-1-yl)prop-2-en-1-one;2-Propen-1-one, 1-[4-[(7R)-6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)-4-quinazolinyl]-1-piperazinyl]-
- CBNumber
- CB13386449
- Molecular Formula
- C21H17ClF2N4O2
- Formula Weight
- 430.84
- MOL File
- 1698055-86-5.mol
ARS-1630 Property
- Boiling point:
- 614.7±55.0 °C(Predicted)
- Density
- 1.434±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO : ≥ 69 mg/mL (160.15 mM)
- pka
- 6.03±0.35(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- CS-0035117
- Product name
- ARS-1630
- Purity
- 98.01%
- Packaging
- 5mg
- Price
- $250
- Updated
- 2021/12/16
- Product number
- CS-0035117
- Product name
- ARS-1630
- Purity
- 98.01%
- Packaging
- 10mg
- Price
- $350
- Updated
- 2021/12/16
- Product number
- CS-0035117
- Product name
- ARS-1630
- Purity
- 98.01%
- Packaging
- 25mg
- Price
- $690
- Updated
- 2021/12/16
- Product number
- CS-0035117
- Product name
- ARS-1630
- Purity
- 98.01%
- Packaging
- 50mg
- Price
- $990
- Updated
- 2021/12/16
- Product number
- CS-0035117
- Product name
- ARS-1630
- Purity
- 98.01%
- Packaging
- 100mg
- Price
- $1300
- Updated
- 2021/12/16
ARS-1630 Chemical Properties,Usage,Production
Definition
ChEBI: ARS-1620 is a qinazoline derivative carrying chloro and fluoro substituents at positions 6 and 8 respectively, a 2-fluoro-6-hydroxyphenyl group at position 7, and a 4-(prop-2-enoyl)piperazin-1-yl group at position 4. A potent, selective, and orally bioavailable covalent KRAS-G12C inhibitor, it inhibits the protein coding gene KRAS (Kirsten rat sarcoma virus) with high potency in cells and animals. It has a role as an inhibitor, an antiviral agent and an antineoplastic agent.
ARS-1630 Preparation Products And Raw materials
Raw materials
Preparation Products
ARS-1630 Suppliers
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