2-Methoxy-5-nitrophenol

Product Name: 2-Methoxy-5-nitrophenol
CAS No.: 636-93-1
Chemical Name: 2-Methoxy-5-nitrophenol
Synonyms: 5-NITROGUAIACOL;NITROGUAIACOL(5-);Methoxy-5-nitrophe;5-Nitroguaiacol>5-nitroguaiacolate;2-Methoxy-5-nitrophe;2-METHOXY-5-NITROPHENOL;2-METHOXY-5-NITROANILINE;2-Hydroxy-4-nitroanisole;5-Nitro-2-Methoxy Phenol
CBNumber: CB1344251
Molecular Formula: C7H7NO4
Formula Weight: 169.13
MOL File: 636-93-1.mol

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2-Methoxy-5-nitrophenol Property

Melting point:: 103-107 °C (lit.)
Boiling point:: 110-112 °C/1 mmHg (lit.)
Density: 1.3375 (estimate)
refractive index: 1.5830 (rough estimate)
Flash point:: 110-112°C/1mm
storage temp.: Inert atmosphere,Room Temperature
solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form: Solid
pka: 8.31±0.19(Predicted)
color: Light Yellow to Light Brown
BRN: 2047074
InChI: InChI=1S/C7H7NO4/c1-12-7-3-2-5(8(10)11)4-6(7)9/h2-4,9H,1H3
InChIKey: KXKCTSZYNCDFFG-UHFFFAOYSA-N
SMILES: C1(O)=CC([N+]([O-])=O)=CC=C1OC
CAS DataBase Reference: 636-93-1(CAS DataBase Reference)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 22-36/37/38
Safety Statements: 26-36
RIDADR: 2811
WGK Germany: 3
Hazard Note: Irritant
PackingGroup: III
HS Code: 29095090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 329274
Product name: 2-Methoxy-5-nitrophenol
Purity: 98%
Packaging: 25g
Price: $96.5
Updated: 2023/06/20

TCI Chemical

Product number: N0498
Product name: 5-Nitroguaiacol
Purity: >98.0%(T)
Packaging: 25g
Price: $27
Updated: 2025/07/31

TCI Chemical

Product number: N0498
Product name: 5-Nitroguaiacol
Purity: >98.0%(T)
Packaging: 500g
Price: $396
Updated: 2025/07/31

TRC

Product number: M266285
Product name: 2-Methoxy-5-nitrophenol
Packaging: 10g
Price: $110
Updated: 2021/12/16

ChemScene

Product number: CS-B1762
Product name: 5-Nitroguaiacol
Purity: 99.92%
Packaging: 100g
Price: $50
Updated: 2021/12/16

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2-Methoxy-5-nitrophenol Chemical Properties,Usage,Production

Chemical Properties

Yellow to light brown powder

Uses

2-Methoxy-5-nitrophenol is used in the synthesis of potent VEGF and tyrosine kinase inhibitors. Also used in the synthesis of GABA analogues and phosphodiesterase inhibitors such as rolipram.

Definition

ChEBI: 2-Methoxy-5-nitrophenol is a member of 3-nitrophenols.

Synthesis Reference(s)

Chemical and Pharmaceutical Bulletin, 28, p. 1287, 1980 DOI: 10.1248/cpb.28.1287

General Description

2-Methoxy-5-nitrophenol is the substitution photoproduct formed on irradiation of 2-chloro-4-nitroanisole at 25°C in aqueous NaOH.

2-Methoxy-5-nitrophenol Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Methoxy-5-nitrophenol Suppliers

Americas 1 Belgium 1 China 244 Czech Republic 1 Europe 3 Germany 7 India 16 Japan 3 Slovakia 1 Switzerland 2 Ukraine 2 United Kingdom 13 United States 34 Global 328

Molekula Limited

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UK GREEN SCIENTIFIC CO.,LIMITED

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Apin Chemicals Ltd.

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VWR International

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View Lastest Price from 2-Methoxy-5-nitrophenol manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: 2-Methoxy-5-nitrophenol 636-93-1
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 5tons
Release date: 2024-12-02

Hebei Chuanghai Biotechnology Co., Ltd

Product: 2-Methoxy-5-nitrophenol 636-93-1
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-10-31

Hebei Yanxi Chemical Co., Ltd.

Product: 2-Methoxy-5-nitrophenol 636-93-1
Price: US $20.00-1.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 10 tons
Release date: 2023-10-26

636-93-1, 2-Methoxy-5-nitrophenolRelated Search:

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636-93-1

CH3OC6H3NO2OH

C7H7NO4

Building Blocks

Phenols

Oxygen Compounds

Organic Building Blocks

Aromatic Phenols

Phenoles and thiophenoles

Building Blocks

C6 to C8

Chemical Synthesis

Organic Building Blocks

Oxygen Compounds

Phenols