Synthesis
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BUTOPYRONOXYL

Synthesis
Product Name
BUTOPYRONOXYL
CAS No.
532-34-3
Chemical Name
BUTOPYRONOXYL
Synonyms
bmoo;ent9;INDALON;INDALONE;INDALONE(R);BUTOPYRONOXYL;dihydropyrone;DIHYDROPYRONE(R);Butopyronoxyl >BUTYLMESITYL OXIDE
CBNumber
CB1345940
Molecular Formula
C12H18O4
Formula Weight
226.27
MOL File
532-34-3.mol
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BUTOPYRONOXYL Property

Melting point:
25°C
Boiling point:
bp760 256-270°
Density 
1.054 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.477(lit.)
Flash point:
>230 °F
storage temp. 
4°C, protect from light
solubility 
DMSO: 100 mg/mL (441.95 mM)
form 
clear liquid
color 
Light orange to Yellow to Green
CAS DataBase Reference
532-34-3
EPA Substance Registry System
Butopyronoxyl (532-34-3)
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Safety

Risk Statements 
38
Safety Statements 
37/39
WGK Germany 
3
RTECS 
UP7000000
HS Code 
29329990
Hazardous Substances Data
532-34-3(Hazardous Substances Data)
Toxicity
LD50 in mice, rats (ml/kg): 11.6, 7.4 orally (Draize)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TCI Chemical
Product number
D0550
Product name
Butopyronoxyl
Packaging
25G
Price
$82
Updated
2024/03/01
TCI Chemical
Product number
D0550
Product name
Butopyronoxyl
Packaging
500G
Price
$703
Updated
2024/03/01
Chem-Impex
Product number
39374
Product name
Butopyronoxyl,95%(HPLC)
Purity
95%(HPLC)
Packaging
500G
Price
$729.12
Updated
2021/12/16
AK Scientific
Product number
6007AF
Product name
Butopyronoxyl
Packaging
25g
Price
$155
Updated
2021/12/16
AK Scientific
Product number
6007AF
Product name
Butopyronoxyl
Packaging
500g
Price
$938
Updated
2021/12/16
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BUTOPYRONOXYL Chemical Properties,Usage,Production

Synthesis

To a 25-mL flflame-dried flflask under a nitrogen atmosphere were added freshly distilled Rawal’s diene (227 mg, 1 mmol, 1.0 equivalents) and 2 mL of CHCl3. Benzaldehyde (1.5 mmol, 1.5 equivalents) was added dropwise via a gas-tight syringe. The reaction mixture was stirred at room temperature for 2 h and then diluted with 15 mL of CH2Cl2. The yellow solution was cooled to −78 °C and treated with 142 µL acetyl chloride (2 mmol, 2 equivalents). After stirring for about 30 min, saturated Na2CO3 was added. The organic layer was separated and the water phase was diluted with 15 mL of water and extracted twice with CH2Cl2. The combined organic phase was dried with MgSO4, fifiltered, and concentrated to give a yellow oil, which was subjected to flflash chromatography to afford the desired dihydropyrone in 86% overall yield. Reference: Huang, Y.; Rawal, V. H. Org. Lett. 2000, 2, 3321−3322.

Chemical Properties

Yellow to pale reddish-brown liquid; aromatic odor. Reasonably stable in air. Slowly affected by light. Insoluble in water; miscible with alcohol, chloroform, ether, glacial acetic acid.

Uses

Insect repellents that can be applied directly on the skin.

Uses

Indalon is an insect repellent.

Definition

ChEBI: Butopyronoxyl is a member of pyrans and a carbonyl compound.

Indications

Butopyronoxyl is not water soluble and can be applied to skin and clothing to repel biting stable flies, Lone Star ticks, dog and cat fleas, and chiggers.

Hazard

Toxic by ingestion. May cause liver dam- age.

Safety Profile

Moderately toxic by ingestion. Produces liver necrosis in experimental animals. A rmld skin irritant. See also OXALATES and ESTERS. Combustible when exposed to heat or flame. When heated to decomposition it emits acrid fumes.

BUTOPYRONOXYL Preparation Products And Raw materials

Raw materials

Preparation Products

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BUTOPYRONOXYL Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11707
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TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28387
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80
TCI Europe
Tel
320-37350700
Fax
+32 (0)37350701
Email
sales@tcieurope.eu
Country
Europe
ProdList
23671
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75
TCI AMERICA
Tel
800-4238616
Fax
+1-888-520-1075 / +1-503-283-1987
Email
sales@tciamerica.com
Country
Americas
ProdList
23653
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9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22514
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55

532-34-3, BUTOPYRONOXYLRelated Search:


  • BUTYL-3,4-DIHYDRO-2,2-DIMETHYL-4-OXO-1,2-H-PYRAN-[6-CARBOXYLATE]
  • BUTYL 3,4-DIHYDRO-2,2-DIMETHYL-4-OXO-2H-PYRAN-6-CARBOXYLATE
  • BUTYLMESITYL OXIDE
  • BUTYLMESITYL OXIDE OXALATE
  • (ALPHA,ALPHA')-DIMETHYL(ALPHA')CARBOBUTOXYDIHYDRO-(GAMMA)-PYRONE
  • 3,4-DIHYDRO-2,2-DIMETHYL-4-OXO-2H-PYRAN-6-CARBOXYLIC ACID BUTYL ESTER
  • 2,2-dimethyl-6-carbobutoxy-2,3-dihydro-4-pyrone
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  • 3,4-dihydro-2,2-dimethyl-4-oxo-2h-pyran-6-carboxylicacibutylester
  • 3,4-dihydro-2,2-dimethyl-4-oxo-2h-pyran-6-carboxylicacid,n-butylester
  • 3,4-dihydro-2,2-dimethyl-4-oxo-2h-pyran-6-carboxylicacid-n-butylester
  • 4-pyrone-2-carboxylicacid-5,6-dihydro-6,6-dimethyl,butylester
  • n-butylesterof3,4-dihydro-2,2-dimethyl-4-oxo-2h-pyran-6-carboxylicacid
  • n-butylmesityloxideoxalate
  • 6-butoxycarbonyl-2,3-dihydro-2,2-dimethyl-4-pyrone
  • 5,6-Dihydro-4-oxo-6,6-dimethyl-4H-pyran-2-carboxylic acid butyl ester
  • Butopyronoxyl,85+%
  • 4-keto-2,2-dimethyl-3H-pyran-6-carboxylic acid butyl ester
  • butyl 2,2-dimethyl-4-oxo-3H-pyran-6-carboxylate
  • Butyl 3,4-Dihydro-2,2-dimethyl-4-oxo-2H-pyran-6-carboxylate 3,4-Dihydro-2,2-dimethyl-4-oxo-2H-pyran-6-carboxylic Acid Butyl Ester Indalone
  • BUTYLMESITYL OXIDE OXALATE, 1GM, NEAT
  • BUTOPYRONOXYL, 85+% (INDALONE)
  • DIHYDROPYRONE(R)
  • INDALON
  • INDALONE
  • INDALONE(R)
  • LABOTEST-BB LT00138120
  • BUTOPYRONOXYL
  • alpha,alpha-dimethyl-alpha’-carboxydihydro-gamma-pyronebutylester
  • bmoo
  • butyl5,6-dihydro-6,6-dimethyl-4-oxo-4h-pyran-2-carboxylate
  • butyldihydro-6,6-dimethyl-4-oxopyran-2-carboxylate
  • dihydropyrone
  • ent9
  • n-butyl-3,4-dihydro-2,2-dimethyl-4-oxo-1,2h-pyran-6-carboxylate
  • Indalone@100 μg/mL in Methanol
  • Butopyronoxyl &gt
  • 532-34-3
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