2-[(4-Methylphenyl)sulfonyl]ethanol
- Product Name
- 2-[(4-Methylphenyl)sulfonyl]ethanol
- CAS No.
- 22381-54-0
- Chemical Name
- 2-[(4-Methylphenyl)sulfonyl]ethanol
- Synonyms
- MPSE;2-TOSYLETHANOL;2-(p-tosyl)ethanol;Toluenesulfonylethanol;2-(P-TOLYLSULFONYL)ETHANOL;2-(P-TOLUENESULFONYL)ETHANOL;2-(P-TOLUENESULPHONYL)ETHANOL;2-(4-Toluenesulfonyl)-ethanol;Ethanol, 2-(p-tolylsulfonyl)-;2-(p-Toluenesulfonyl)ethanol,98%
- CBNumber
- CB1355655
- Molecular Formula
- C9H12O3S
- Formula Weight
- 200.25
- MOL File
- 22381-54-0.mol
2-[(4-Methylphenyl)sulfonyl]ethanol Property
- Melting point:
- 50-56 °C (lit.)
- Boiling point:
- 178-181 °C/0.2 mmHg (lit.)
- Density
- 1.2922 (rough estimate)
- refractive index
- 1.4998 (estimate)
- Flash point:
- 178-181°C/0.2mm
- storage temp.
- Sealed in dry,Room Temperature
- form
- solid
- pka
- 13.73±0.10(Predicted)
- Appearance
- White to off-white Solid
- Water Solubility
- Slightly soluble in water.
- BRN
- 1961132
- CAS DataBase Reference
- 22381-54-0(CAS DataBase Reference)
- EPA Substance Registry System
- Ethanol, 2-[(4-methylphenyl)sulfonyl]- (22381-54-0)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 446386
- Product name
- 2-(p-Tolylsulfonyl)ethanol
- Purity
- 97%
- Packaging
- 10g
- Price
- $328
- Updated
- 2023/06/20
- Product number
- T1620
- Product name
- 2-(p-Toluenesulfonyl)ethanol
- Purity
- >95.0%(GC)
- Packaging
- 5g
- Price
- $80
- Updated
- 2022/04/27
- Product number
- CHM0019077
- Product name
- 2-(P-TOLUENESULFONYL)ETHANOL
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $628.44
- Updated
- 2021/12/16
- Product number
- 008058
- Product name
- 2-(p-Toluenesulfonyl)ethanol
- Purity
- 98%
- Packaging
- 1g
- Price
- $20
- Updated
- 2021/12/16
- Product number
- 9335AJ
- Product name
- 2-(p-Toluenesulfonyl)ethanol
- Packaging
- 5g
- Price
- $180
- Updated
- 2021/12/16
2-[(4-Methylphenyl)sulfonyl]ethanol Chemical Properties,Usage,Production
Chemical Properties
WHITE TO OFF-WHITE ADHERING CRYSTALS
Uses
2-(p-Toluenesulfonyl)ethanol is used as an organic chemical synthesis intermediate.
Synthesis
699-02-5
22381-54-0
General procedure for the synthesis of 2-(p-toluenesulfonyl)ethanol from 4-methylphenylethanol: To a mixture of acetic acid (50 mL) and water (50 mL) of compound 2 (20 g, 0.119 mol) was added slowly and dropwise over a period of one-half hour 30% hydrogen peroxide (36.5 mL) under ice-bath conditions. Subsequently, the reaction mixture was refluxed for 20 minutes and then cooled to room temperature. Sodium bicarbonate was added to the reaction mixture to neutralize the solution, followed by ethyl acetate for extraction. The organic layer was separated, washed sequentially with saturated saline and deionized water, and finally concentrated under reduced pressure to give 22.9 g (96.3% yield) of target product 3 as a white solid. The structure of the product was confirmed by 1H NMR (270 MHz, CDCl3) and 13C NMR (67.9 MHz, CDCl3): 1H NMR (270 MHz, CDCl3) δ 2.46 (s, 3H), 3.33 (t, J = 5.4 Hz, 2H), 3.99 (t, J = 5.4 Hz, 2H), 7.39 (d, J = 8.0 Hz, 2H), 7.81 (d, J = 8.3 Hz, 2H); 13C NMR (67.9 MHz, CDCl3) δ 21.7, 56.4, 58.3, 128.0, 130.1, 136.0, 145.2.
References
[1] Patent: WO2007/64291, 2007, A1. Location in patent: Page/Page column 17
2-[(4-Methylphenyl)sulfonyl]ethanol Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-[(4-Methylphenyl)sulfonyl]ethanol manufacturers
- Product
- 2-[(4-Methylphenyl)sulfonyl]ethanol 22381-54-0
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11
- Product
- 2-[(4-Methylphenyl)sulfonyl]ethanol 22381-54-0
- Price
- US $6.60/KG
- Min. Order
- 500g
- Purity
- 98%
- Supply Ability
- 50g, 1kg, 50kg,100kg
- Release date
- 2019-12-23