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CMP-NAN SODIUM SALT

Product Name
CMP-NAN SODIUM SALT
CAS No.
1007117-62-5
Chemical Name
CMP-NAN SODIUM SALT
Synonyms
CMP-NAN SODIUM SALT;CMP-NANA SODIUM SALT;CMP-SIALIC ACID SODIUM SALT;CMPSialic acid sodium salt,CMP Sialic acid sodium salt;Cytidine-5'-monophospho-N-acetylneuraminic acid sodium Salt;CYTIDINE 5'-MONOPHOSPHO-N-ACETYLNEURAMINIC ACID SODIUM SALT;sodium:(2R,4S,5R,6R)-5-acetamido-2-[[(2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylate
CBNumber
CB1358090
Molecular Formula
C20H32N4NaO16P
Formula Weight
638.45
MOL File
Mol file
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CMP-NAN SODIUM SALT Property

storage temp. 
−20°C
solubility 
PBS (pH 7.2): 10 mg/ml
form 
A crystalline solid
color 
White to off-white
biological source
synthetic (organic)
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Safety

WGK Germany 
3
10-21
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C8271
Product name
Cytidine-5′-monophospho-N-acetylneuraminic acid sodium salt
Purity
≥85% (HPLC)
Packaging
1mg
Price
$103
Updated
2025/07/31
Sigma-Aldrich
Product number
C8271
Product name
Cytidine-5′-monophospho-N-acetylneuraminic acid sodium salt
Purity
≥85% (HPLC)
Packaging
5mg
Price
$401
Updated
2025/07/31
Sigma-Aldrich
Product number
C8271
Product name
Cytidine-5′-monophospho-N-acetylneuraminic acid sodium salt
Purity
≥85% (HPLC)
Packaging
25mg
Price
$1530
Updated
2025/07/31
Cayman Chemical
Product number
16404
Product name
CMP-Sialic Acid (sodium salt)
Purity
≥85%
Packaging
1mg
Price
$57
Updated
2024/03/01
Cayman Chemical
Product number
16404
Product name
CMP-Sialic Acid (sodium salt)
Purity
≥85%
Packaging
5mg
Price
$179
Updated
2024/03/01
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CMP-NAN SODIUM SALT Chemical Properties,Usage,Production

Description

CMP-Sialic acid is a form of the sugar N-acetylneuraminic acid (Neu5Ac) O-linked with the nucleotide cytidine-5’-monophosphate (CMP). In vertebrates, it is biosynthesized within the nucleus from CTP and Neu5Ac by CMP-sialic acid synthetases. Sialyltransferases transfer Neu5Ac from CMP-sialic acid to various acceptor substrates, most commonly at terminal positions of the oligosaccharide component of glycoproteins or glycolipids. Sialic acid-containing glycans at the cell surface play important roles in cell interactions and have roles in infection, inflammation, and cancer.

Uses

CMP-N-acetylneuraminic acid sodium salt is a nucleotide and CMP-?sialic acid derivative used as a building block used in the preparation of N-?glycan microarrays.

IC 50

Human Endogenous Metabolite

References

[1] ANJA K MüNSTER-KüHNEL. Structure and function of vertebrate CMP-sialic acid synthetases.[J]. Glycobiology, 2004, 14 10: 43R-51R. DOI: 10.1093/glycob/cwh113
[2] TSUJI S. Molecular cloning and functional analysis of sialyltransferases.[J]. Journal of biochemistry, 1996, 120 1: 1-13. DOI: 10.1093/oxfordjournals.jbchem.a021369
[3] MAGALI AUDRY. Current trends in the structure-activity relationships of sialyltransferases.[J]. Glycobiology, 2011, 21 6: 716-726. DOI: 10.1093/glycob/cwq189
[4] HENNET T. From glycosylation disorders back to glycosylation: What have we learned?[J]. Biochimica et biophysica acta. Molecular basis of disease, 2009, 1792 9: Pages 921-924. DOI: 10.1016/j.bbadis.2008.10.006
[5] ANNIE N SAMRAJ. Involvement of a non-human sialic Acid in human cancer.[J]. Frontiers in Oncology, 2014: 33. DOI: 10.3389/fonc.2014.00033

CMP-NAN SODIUM SALT Preparation Products And Raw materials

Raw materials

Preparation Products

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CMP-NAN SODIUM SALT Suppliers

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1007117-62-5, CMP-NAN SODIUM SALTRelated Search:


  • CYTIDINE 5'-MONOPHOSPHO-N-ACETYLNEURAMINIC ACID SODIUM SALT
  • CMP-NANA SODIUM SALT
  • CMP-NAN SODIUM SALT
  • CMP-SIALIC ACID SODIUM SALT
  • sodium:(2R,4S,5R,6R)-5-acetamido-2-[[(2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylate
  • CMPSialic acid sodium salt,CMP Sialic acid sodium salt
  • Cytidine-5'-monophospho-N-acetylneuraminic acid sodium Salt
  • 1007117-62-5