CMP-NAN SODIUM SALT
- Product Name
- CMP-NAN SODIUM SALT
- CAS No.
- 1007117-62-5
- Chemical Name
- CMP-NAN SODIUM SALT
- Synonyms
- CMP-NAN SODIUM SALT;CMP-NANA SODIUM SALT;CMP-SIALIC ACID SODIUM SALT;CMPSialic acid sodium salt,CMP Sialic acid sodium salt;Cytidine-5'-monophospho-N-acetylneuraminic acid sodium Salt;CYTIDINE 5'-MONOPHOSPHO-N-ACETYLNEURAMINIC ACID SODIUM SALT;sodium:(2R,4S,5R,6R)-5-acetamido-2-[[(2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylate
- CBNumber
- CB1358090
- Molecular Formula
- C20H32N4NaO16P
- Formula Weight
- 638.45
- MOL File
- Mol file
CMP-NAN SODIUM SALT Property
- storage temp.
- −20°C
- solubility
- PBS (pH 7.2): 10 mg/ml
- form
- A crystalline solid
- color
- White to off-white
- biological source
- synthetic (organic)
Safety
- WGK Germany
- 3
- F
- 10-21
N-Bromosuccinimide Price
- Product number
- C8271
- Product name
- Cytidine-5′-monophospho-N-acetylneuraminic acid sodium salt
- Purity
- ≥85% (HPLC)
- Packaging
- 1mg
- Price
- $103
- Updated
- 2025/07/31
- Product number
- C8271
- Product name
- Cytidine-5′-monophospho-N-acetylneuraminic acid sodium salt
- Purity
- ≥85% (HPLC)
- Packaging
- 5mg
- Price
- $401
- Updated
- 2025/07/31
- Product number
- C8271
- Product name
- Cytidine-5′-monophospho-N-acetylneuraminic acid sodium salt
- Purity
- ≥85% (HPLC)
- Packaging
- 25mg
- Price
- $1530
- Updated
- 2025/07/31
- Product number
- 16404
- Product name
- CMP-Sialic Acid (sodium salt)
- Purity
- ≥85%
- Packaging
- 1mg
- Price
- $57
- Updated
- 2024/03/01
- Product number
- 16404
- Product name
- CMP-Sialic Acid (sodium salt)
- Purity
- ≥85%
- Packaging
- 5mg
- Price
- $179
- Updated
- 2024/03/01
CMP-NAN SODIUM SALT Chemical Properties,Usage,Production
Description
CMP-Sialic acid is a form of the sugar N-acetylneuraminic acid (Neu5Ac) O-linked with the nucleotide cytidine-5’-monophosphate (CMP). In vertebrates, it is biosynthesized within the nucleus from CTP and Neu5Ac by CMP-sialic acid synthetases. Sialyltransferases transfer Neu5Ac from CMP-sialic acid to various acceptor substrates, most commonly at terminal positions of the oligosaccharide component of glycoproteins or glycolipids. Sialic acid-containing glycans at the cell surface play important roles in cell interactions and have roles in infection, inflammation, and cancer.
Uses
CMP-N-acetylneuraminic acid sodium salt is a nucleotide and CMP-?sialic acid derivative used as a building block used in the preparation of N-?glycan microarrays.
IC 50
Human Endogenous Metabolite
References
[1] ANJA K MüNSTER-KüHNEL. Structure and function of vertebrate CMP-sialic acid synthetases.[J]. Glycobiology, 2004, 14 10: 43R-51R. DOI: 10.1093/glycob/cwh113
[2] TSUJI S. Molecular cloning and functional analysis of sialyltransferases.[J]. Journal of biochemistry, 1996, 120 1: 1-13. DOI: 10.1093/oxfordjournals.jbchem.a021369
[3] MAGALI AUDRY. Current trends in the structure-activity relationships of sialyltransferases.[J]. Glycobiology, 2011, 21 6: 716-726. DOI: 10.1093/glycob/cwq189
[4] HENNET T. From glycosylation disorders back to glycosylation: What have we learned?[J]. Biochimica et biophysica acta. Molecular basis of disease, 2009, 1792 9: Pages 921-924. DOI: 10.1016/j.bbadis.2008.10.006
[5] ANNIE N SAMRAJ. Involvement of a non-human sialic Acid in human cancer.[J]. Frontiers in Oncology, 2014: 33. DOI: 10.3389/fonc.2014.00033
CMP-NAN SODIUM SALT Preparation Products And Raw materials
Raw materials
Preparation Products
CMP-NAN SODIUM SALT Suppliers
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- Country
- Switzerland
- ProdList
- 6896
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