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Prasugrel-d5

Product Name
Prasugrel-d5
CAS No.
1127252-92-9
Chemical Name
Prasugrel-d5
Synonyms
[2H5]-Prasugrel;DTGLZDAWLRGWQN-GEXSZOTCSA-N
CBNumber
CB13586553
Molecular Formula
C20H20FNO3S
Formula Weight
373.44
MOL File
1127252-92-9.mol
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Prasugrel-d5 Property

storage temp. 
Store at -20°C
solubility 
Chloroform: slightly soluble,Methanol: slightly soluble
form 
A solid
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
28160
Product name
Prasugrel-d5
Packaging
1mg
Price
$335
Updated
2024/03/01
TRC
Product number
P701152
Product name
Prasugrel-d5
Packaging
10mg
Price
$1455
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
D33757
Product name
Prasugrel-d4
Packaging
1mg
Price
$990
Updated
2021/12/16
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Prasugrel-d5 Chemical Properties,Usage,Production

Description

Prasugrel-d5 is intended for use as an internal standard for the quantification of prasugrel by GC- or LC-MS. Prasugrel is a prodrug form of the platelet purinergic P2Y12 receptor antagonist R-99224. Prasugrel (0.3 and 3 mg/kg) inhibits ex vivo washed platelet aggregation in rat platelet rich-plasma. In vivo, prasugrel prevents thrombus formation (ED50 = 0.68 mg/kg) and increases tail bleeding time in rats. Formulations containing prasugrel have been used in the prevention of blood clots.

Uses

A novel labelled antiplatelet agent; it is a third-generation thienopyridine. Antiplatelet agent Prasugrel showed greater platelet inhibition and decreased incidence of ischemic events than Clopidogrel but may induce increased incidence of bleeding in patient with acute coronary syndrome

IC 50

P2Y12 Receptor

References

[1] A. SUGIDACHI. Antiplatelet action of R‐99224, an active metabolite of a novel thienopyridine‐type Gi‐linked P2T antagonist, CS‐747[J]. British Journal of Pharmacology, 2001, 132 1. DOI: 10.1038/sj.bjp.0703761
[2] ATSUHIRO SUGIDACHI. The in vivo pharmacological profile of CS-747, a novel antiplatelet agent with platelet ADP receptor antagonist properties[J]. British Journal of Pharmacology, 2009, 129 7: 1439-1446. DOI: 10.1038/sj.bjp.0703237

Prasugrel-d5 Preparation Products And Raw materials

Raw materials

Preparation Products

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Prasugrel-d5 Suppliers

China 9 India 1 United States 2 Global 12
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing1@energy-chemical.com
Country
China
ProdList
44894
Advantage
58
Shanghai isotope chemical co.,ltd
Tel
021-51600108 13062666369
Email
sales@isotopechem.com
Country
China
ProdList
5000
Advantage
58
Nanjing Shizhou Biology Technology Co.,Ltd
Tel
17301488900
Fax
025-85560043
Email
judy.xia@synzest.com
Country
China
ProdList
12582
Advantage
58
Cayman Chemical Company
Tel
800-364-9897
Email
sales@caymanchem.com
Country
China
ProdList
6838
Advantage
58
Biosynth Biological Technology (Suzhou) Co Ltd
Tel
51288865780
Email
sales@biosynth.com
Country
China
ProdList
6051
Advantage
58
Santa Cruz Biotechnology Inc
Tel
021-60936350
Email
scbt@scbt.com
Country
China
ProdList
6594
Advantage
58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
52923
Advantage
58

1127252-92-9, Prasugrel-d5Related Search:

1-cyclopropyl-2-(2-fluorophenyl)ethane-1,2-dione 2-Desacetoxy Prasugrel 5-(2-cyclopropyl-1-(4-fluorophenyl) -2-oxoethyl)-4,5,6,7-tetrahydrothieno [3,2-c]pyridin-2-yl acetate 5-[2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2(3H)-one 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone Mesna Methyl Ester 2-Bromo Analog Prasugrel Metabolite M5 PRASUGREL METABOLITE R-138727 IZCHRAOWOKMDHU-UHFFFAOYSA-N Cyclopropyl 4-Fluorobenzyl Ketone 2-BroMo-1-cyclopropyl-2-(3-fluorophenyl)ethanone trans-R-138727 1,2-Dihydro-4,6-diMethyl-2-thioxo-3-pyridinecarboxaMide Prasugrel Impurity 26 HCl Prasugrel alpha-Hydroxy IMpurity Prasugrel IMpurity (1-BroMo-5-chloro-1-(2-fluorophenyl)pentan-2-one) 5-(2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-7a-hydroxy-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one 2-BroMo-1-cyclopropyl-2-(4-fluorophenyl)ethanone

  • DTGLZDAWLRGWQN-GEXSZOTCSA-N
  • [2H5]-Prasugrel
  • 1127252-92-9