2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone

Product Name: 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone
CAS No.: 204205-33-4
Chemical Name: 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone
Synonyms: 2-broMo-1-cyclopropyl-2-(2-fluorophenyl)ethan-1-one;PL-02;Prasugrel IMP;Prasugrel IMpurity;Pragrel intermediate;Prasugrel Impurity 46;Prasugrel Intermediate 4;2-Bromo-2-(2-fluorophenyl);Chemical intermediate for Prasugrel;Prasugrel alpha-Bromo 2-Fluoro Impurity
CBNumber: CB31872230
Molecular Formula: C11H10BrFO
Formula Weight: 257.1
MOL File: 204205-33-4.mol

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2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone Property

Boiling point:: 293.0±25.0 °C(Predicted)
Density: 1.574±0.06 g/cm3(Predicted)
Flash point:: 131°
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
solubility: Chloroform (Sparingly), Ethyl Acetate (Slightly)
form: Oil to Low-Melting Solid
form: Oil to Low-Melting Solid
color: Yellow to Light Brown
optical activity: 0.0900°(C=1g/100mL, CHCL3, 20°C, 589nm)
CAS DataBase Reference: 204205-33-4(CAS DataBase Reference)

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Safety

HS Code: 2914.79.4000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

TCI Chemical

Product number: B6031
Product name: 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone
Packaging: 1G
Price: $42
Updated: 2025/07/31

TCI Chemical

Product number: B6031
Product name: 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone
Packaging: 5G
Price: $146
Updated: 2025/07/31

TRC

Product number: B688795
Product name: 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone(90%purity)
Packaging: 5g
Price: $675
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB36572
Product name: 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone
Packaging: 2g
Price: $400
Updated: 2021/12/16

SynQuest Laboratories

Product number: 2717-B-04
Product name: 2-Bromo-1-cyclopropyl-2-(2-fluorophenyl)ethan-1-one
Purity: 96%
Packaging: 250mg
Price: $491
Updated: 2021/12/16

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2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone Chemical Properties,Usage,Production

Uses

2-?Bromo-?2-?(2-?fluorophenyl)?-?1-?cyclopropylethanone is a reagent used in the synthesis of potent anti-oxidant agents.

Synthesis

150322-73-9

204205-33-4

General procedure for the synthesis of 2-bromo-2-(2-fluorophenyl)-1-cyclopropylethanone from 1-cyclopropyl-2-(2-fluorophenyl)ethanone: 1-cyclopropyl-2-(2-fluorophenyl)ethanone (17.8 g, 100 mmol), iodine monobromide (62 g, 300 mmol), and 1-butyl-3-methylimidazolium bromide (8.7 g, 40 mmol) were dissolved in 150 mL of anhydrous tetrahydrofuran. The reaction was stirred at 40 °C for 4 hours. After completion of the reaction, the mixture was cooled to room temperature and the reaction was quenched by the addition of ice water. The reaction mixture was extracted with ethyl acetate and the organic phase was washed with saturated sodium bisulfite solution. The organic phase was concentrated and purified by recrystallization from ethanol to give 2-bromo-2-(2-fluorophenyl)-1-cyclopropylethanone (24.5 g, 95.3% yield, 99.73% purity).

References

[1] Patent: CN105884793, 2016, A. Location in patent: Paragraph 0033; 0034; 0035
[2] Patent: WO2013/14295, 2013, A1. Location in patent: Page/Page column 19-20
[3] Patent: WO2009/122440, 2009, A1. Location in patent: Page/Page column 31
[4] Patent: CN105884599, 2016, A. Location in patent: Paragraph 0025; 0062-0064
[5] Patent: CN104418718, 2018, B. Location in patent: Paragraph 0040; 0044; 0047; 0048; 0052; 0056

2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone Suppliers

Americas 1 China 219 Europe 1 India 19 Japan 1 United Kingdom 1 United States 10 Global 252

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Aemon Chemical

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View Lastest Price from 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone manufacturers

ZHUHAI HRD PHARMACEUTICAL CO., LTD.

Product: 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone 204205-33-4
Price: US $0.00/KG Ton
Min. Order: 1KG Ton
Purity: 93%+
Supply Ability: 2 tons/month
Release date: 2022-10-09

Zhuozhou Wenxi import and Export Co., Ltd

Product: 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone 204205-33-4
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone 204205-33-4
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-08

204205-33-4, 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanoneRelated Search:

5,6,7,7a-Tetrahydrothieno[3,2-c]pyridine-2(4H)-one hydrochloride 3-Methyl-2-butanone Heptafluoroisopropyl iodide 2-Bromopropane Cyclopropyl methyl ketone Cyclopropyl bromide N-Methyl-2-pyrrolidone Allyl bromide Propargyl bromide Cyclopropyl 4-Fluorobenzyl Ketone 2-BroMo-1-cyclopropyl-2-(3-fluorophenyl)ethanone (3R,4R)-3-[(6-amino-4-pyrimidinyl)methylamino]-4-methyl-β-oxo-1-Piperidinepropanenitrile 7-(4-Hydroxybutoxy-4,4-d2)-2(1H)-quinolinone (1R,3S)-1-(1,3-Benzodioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl Ester BENZOOXAZOL-2-YLAMINE Etoricoxib IMpurity Trelagliptin IMpurity pranoprofen

Prasugrel Intermediate 4

2-Bromo-2-(2-fluorophenyl)

Ethanone, 2-bromo-1-cyclopropyl-2-(2-fluorophenyl)-

2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone

Cylopropylcarbonyl-2-flurobenzyl bromide

2-Bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone

Chemical intermediate for Prasugrel

2-broMo-1-cyclopropyl-2-(2-fluorophenyl)ethan-1-one

Prasugrel IMpurity

PL-02

α - cyclopropyl carbonyl -2- fluorine benzyl bromide

Prasugrel IMP

2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone in stock Factory

2-fluoro-α-cyclopropyl carbonyl benzyl bromide

2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone (90% purity)

Prasugrel alpha-Bromo 2-Fluoro Impurity

Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone

Cyclopropylcarbonyl-2-fluorobenzyl bromide

2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanoneQ: What is 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone Q: What is the CAS Number of 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone Q: What is the storage condition of 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone Q: What are the applications of 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone

2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone 204205-33-4

α-(Cyclopropylcarbonyl)-2-fluorobenzyl bromide

Prasugrel Impurity 46

Pragrel intermediate

Prasugrel Impurity 12 2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethan-1-one

2-Bromo-2-(2-fluorophenyl)cyclopropanone

204205-33-4

C11H10BrFO