ChemicalBook > CAS DataBase List > 5,6,7,7a-Tetrahydrothieno[3,2-c]pyridine-2(4H)-one hydrochloride

5,6,7,7a-Tetrahydrothieno[3,2-c]pyridine-2(4H)-one hydrochloride

Product Name
5,6,7,7a-Tetrahydrothieno[3,2-c]pyridine-2(4H)-one hydrochloride
CAS No.
115473-15-9
Chemical Name
5,6,7,7a-Tetrahydrothieno[3,2-c]pyridine-2(4H)-one hydrochloride
Synonyms
PL-01;2-oxo-2,4,5;Pragrael intermediate;7a-Tetrahydrothieno[3;Prasugrel intermediate;Prasugrel InterMediate 1;Prasugrel IMpurity 9 HCl;THIENOTETRAHYDROPYRIDIN ONE;Prasugrel Impurity 9 Hydrochloride;5,6,7,7a-Tetrahydrothieno[3,2-c<
CBNumber
CB61175936
Molecular Formula
C7H10ClNOS
Formula Weight
191.67
MOL File
115473-15-9.mol
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5,6,7,7a-Tetrahydrothieno[3,2-c]pyridine-2(4H)-one hydrochloride Property

Melting point:
2100C (dec)
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
solubility 
DMSO, Methanol, Water
form 
Solid
color 
Light Tan
InChI
InChI=1S/C7H9NOS.ClH/c9-7-3-5-4-8-2-1-6(5)10-7;/h3,6,8H,1-2,4H2;1H
InChIKey
PUQKTVAKLPDUAW-UHFFFAOYSA-N
SMILES
O=C1SC2CCNCC2=C1.Cl
CAS DataBase Reference
115473-15-9(CAS DataBase Reference)
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Safety

Safety Statements 
24/25
HazardClass 
IRRITANT
HS Code 
29349990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TCI Chemical
Product number
T2984
Product name
5,6,7,7a-Tetrahydrothieno[3,2-c]pyridin-2(4H)-one Hydrochloride
Purity
>97.0%(T)
Packaging
1g
Price
$77
Updated
2025/07/31
TCI Chemical
Product number
T2984
Product name
5,6,7,7a-Tetrahydrothieno[3,2-c]pyridin-2(4H)-one Hydrochloride
Purity
>97.0%(T)
Packaging
5g
Price
$262
Updated
2025/07/31
TRC
Product number
T295780
Product name
5,6,7,7a-Tetrahydrothieno[3,2-c]pyridinoneHydrochloride
Packaging
1g
Price
$80
Updated
2021/12/16
Matrix Scientific
Product number
054267
Product name
2H,4H,5H,6H,7H,7AH-Thieno[3,2-c]pyridin-2-onehydrochloride
Purity
95+%
Packaging
1g
Price
$29
Updated
2021/12/16
AK Scientific
Product number
B634
Product name
5,6,7,7a-Tetrahydrothieno(3,2-c)pyridine-2(4H)-oneHCl
Packaging
5g
Price
$85
Updated
2021/12/16
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5,6,7,7a-Tetrahydrothieno[3,2-c]pyridine-2(4H)-one hydrochloride Chemical Properties,Usage,Production

Chemical Properties

Cream Solid

Uses

Solifenacin intermediate

Uses

An intermediate in the synthesis of Prasugrel (P701150).

Synthesis

Hydrochloride (0.32 ml) was added in a solution of 5-Triphenyl methyl-tetrahydro-5, 6, 7,7a 4H- theino-[3,2-c]- pyridone-2 (100 g, 0.25 moles) in acetone (500 ml) at 25 °C. Stir the reaction mass for 1 hr at 50 °C, then cool the reaction mass to 25 °C and stir for 8 to 10 hrs at 25 °C. Filter the product and wash it with acetone. Dry the material under vacuum at 60 °C to obtain 5, 6, 7,7a -Tetrahydro-4H- theino-[3,2-c]- pyridone-2 hydrochloride (42 g, 99percent).

References

[1] Patent: WO2012/1486, 2012, A1. Location in patent: Page/Page column 20
[2] Journal of Organic Chemistry, 2015, vol. 80, # 14, p. 7019 - 7032
[3] Patent: WO2009/62044, 2009, A2. Location in patent: Page/Page column 40
[4] Patent: WO2011/42918, 2011, A2. Location in patent: Page/Page column 43-44
[5] Patent: WO2011/92720, 2011, A2. Location in patent: Scheme 1

5,6,7,7a-Tetrahydrothieno[3,2-c]pyridine-2(4H)-one hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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5,6,7,7a-Tetrahydrothieno[3,2-c]pyridine-2(4H)-one hydrochloride Suppliers

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View Lastest Price from 5,6,7,7a-Tetrahydrothieno[3,2-c]pyridine-2(4H)-one hydrochloride manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
5,6,7,7a-Tetrahydrothieno[3,2-c]pyridine-2(4H)-one hydrochloride 115473-15-9
Price
US $0.00/g
Min. Order
100g
Purity
98%min
Supply Ability
100kg
Release date
2022-12-29
Qingdao RENAS Polymer Material Co., Ltd.
Product
5,6,7,7a-Tetrahydrothieno[3,2-c]pyridine-2(4H)-one hydrochloride 115473-15-9
Price
US $0.00/kg
Min. Order
20kg
Purity
99%
Supply Ability
20 tons
Release date
2024-10-29
PUSHAN INDUSTRIAL (SHAANXI) CO.,LTD
Product
5,6,7,7a-Tetrahydrothieno[3,2-c]pyridine-2(4H)-one hydrochloride 115473-15-9
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
2 MTs
Release date
2024-05-13

115473-15-9, 5,6,7,7a-Tetrahydrothieno[3,2-c]pyridine-2(4H)-one hydrochlorideRelated Search:

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  • 115473-15-9
  • 1115473-15-9
  • 115437-15-9
  • 115473-15-4
  • C7H9NOSHCl
  • Heterocyclic Compounds
  • Heterocycles
  • Sulfur & Selenium Compounds