D-Glucosamine hydrochloride
- Product Name
- D-Glucosamine hydrochloride
- CAS No.
- 66-84-2
- Chemical Name
- D-Glucosamine hydrochloride
- Synonyms
- GLUCOSAMINE HYDROCHLORIDE;GLUCOSAMINE HCL;D-GLUCOSAMINE HCL;D-Glucosamine Salt;Glucosamine for system suitability CRS;2-amino-2-deoxy-D-glucose hydrochloride (1:1);cosamin;NSC 758;D-GLCN HCL;NSC 234443
- CBNumber
- CB2181059
- Molecular Formula
- C6H14ClNO5
- Formula Weight
- 215.63
- MOL File
- 66-84-2.mol
D-Glucosamine hydrochloride Property
- Melting point:
- 190-194 °C (dec.)(lit.)
- alpha
- 72.5 º (c=2, H2O, 5hrs.)
- refractive index
- 72 ° (C=1, H2O)
- storage temp.
- 2-8°C
- solubility
- H2O: 0.1 g/mL, clear, colorless
- form
- crystalline
- color
- White
- Water Solubility
- soluble
- Merck
- 14,4458
- BRN
- 4157370
- Stability:
- Stable. Incompatible with strong oxidizing agents. Combustible.
- InChI
- InChI=1/C6H13NO5.ClH/c7-3-5(10)4(9)2(1-8)12-6(3)11;/h2-6,8-11H,1,7H2;1H/t2-,3-,4-,5-,6?;/s3
- InChIKey
- QKPLRMLTKYXDST-LPRXMDNASA-N
- SMILES
- [C@H]1(CO)OC([C@H](N)[C@@H](O)[C@@H]1O)O.Cl |&1:0,5,7,9,r|
- LogP
- -2.375 (est)
- CAS DataBase Reference
- 66-84-2(CAS DataBase Reference)
- EPA Substance Registry System
- D-Glucose, 2-amino-2-deoxy-, hydrochloride (66-84-2)
Safety
- Hazard Codes
- F,Xi,Xn
- Risk Statements
- 21-36/38-46-62-63
- Safety Statements
- 24/25-53-36/37-26-25
- WGK Germany
- 2
- RTECS
- LZ6665000
- F
- 3-10
- Hazard Note
- Highly Flammable
- TSCA
- Yes
- HS Code
- 29329985
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- G1514
- Product name
- D-(+)-Glucosamine hydrochloride
- Purity
- ≥99%, BioReagent, suitable for cell culture
- Packaging
- 100g
- Price
- $75.7
- Updated
- 2023/01/07
- Product number
- 1294207
- Product name
- Glucosamine hydrochloride
- Purity
- United States Pharmacopeia (USP) Reference Standard
- Packaging
- 200mg
- Price
- $361
- Updated
- 2022/05/15
- Product number
- G0044
- Product name
- D-(+)-Glucosamine Hydrochloride
- Purity
- >98.0%(T)
- Packaging
- 25g
- Price
- $24
- Updated
- 2023/01/07
- Product number
- G0044
- Product name
- D-(+)-Glucosamine Hydrochloride
- Purity
- >98.0%(T)
- Packaging
- 500g
- Price
- $136
- Updated
- 2023/01/07
- Product number
- A15532
- Product name
- D-Glucosamine hydrochloride, 98+%
- Packaging
- 50g
- Price
- $33.81
- Updated
- 2023/01/06
D-Glucosamine hydrochloride Chemical Properties,Usage,Production
Chemical Properties
white powder
Uses
Novel application of D-Glucosamine hydrochloride to prepare medical agent for treating vertigo. Found in chitin, in mucoproteins, and in mucopolysaccharides. Antiarthritic. Recent studies show that its chondroprotective activity is related to its antiapoptic properties.
Uses
glucosamine hydrochloride (glucosamine HCl) is used to adjust the pH of a formulation. It also has anti-static and hair-conditioning properties.
Uses
Novel application of glucosamine is to prepare medical agent for treating vertigo. It is used as food ingredients and additives, raw material for anti cancer and antibiotic drugs.
General Description
Glucosamine, an amino sugar is generated form glucose and glutamine and is naturally produced in the body. Glucosamine, a endogenous amino monosaccharide is the major source of glucosamine-6-phosphate and n-acetylglucosamine.
Biochem/physiol Actions
Glucosamine is preferred as a nutritional supplement?for individuals with osteoarthritis. It is used as a building block for the production of proteoglycans?and?glycosaminoglycans.
Purification Methods
Crystallise the hydrochloride from 3M HCl, water, and finally water/EtOH/acetone as for galactosamine hydrochloride. [Purchase & Braun Org Synth 26 36 1946, Stacey & Webber Methods in Carbohydrate Chemistry I 228 1962, Academic Press.] The salt has also been purified by dissolving in the minimum volume of boiling H2O (charcoal), filtering and adding a large excess of 95% EtOH (~4 volumes) and stirring vigorously for several hours. Collect the crystals after 4-6hours to give anomer which mutarotates ] D +100o to +72o (equilibrium, c 1, H2O). A large amount of the -anomer stays in solution. This can be precipitated from the filtrate by adding excess Et2O. The mixture of -plus -anomers has [] D +68.8o (c 4.75, H2O, mutarotating to +70.1o)[Leaback Biochemical Preparations 10 118 1963]. Note that if Et2NH is used instead of Et3N, conversion to the -anomer can be complete (see above). [Stacey et al. Methods in Carbohydrate Chemistry I 3061962, Academic Press; Beilstein 4 IV 2018.]
D-Glucosamine hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from D-Glucosamine hydrochloride manufacturers
- Product
- D-Glucosamine hydrochloride 66-84-2
- Price
- US $8.00-7.00/kg
- Min. Order
- 10kg
- Purity
- 99%
- Supply Ability
- 100Tons
- Release date
- 2023-03-03
- Product
- D-Glucosamine hydrochloride 66-84-2
- Price
- US $10.00-15.00/g
- Min. Order
- 10g
- Purity
- 99%
- Supply Ability
- 2546245
- Release date
- 2022-11-03
- Product
- Glucosamine Hydrochloride 66-84-2
- Price
- US $1.90/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 ton
- Release date
- 2021-08-02