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Aminoacetonitrile hydrochloride

Product Name
Aminoacetonitrile hydrochloride
CAS No.
6011-14-9
Chemical Name
Aminoacetonitrile hydrochloride
Synonyms
Glycinonitrile hydrochloride;e hydrochL;GlycinonitrileHCl;Aminoacetonitrile hy;AMINO ACETONITRILE HCL;Acetonitrile hydrochloride;Cyanomethylazanium chloride;Aminoacetonitrilhydrochlorid;AMINOACETONITRILE HYDROCHLORIDE;2-AminoacetonitrileHydrochloride
CBNumber
CB2181554
Molecular Formula
C2H5ClN2
Formula Weight
92.53
MOL File
6011-14-9.mol
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Aminoacetonitrile hydrochloride Property

Melting point:
172-174°C
RTECS 
MC1950000
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Methanol (Slightly, Heated), Water
form 
Powder
color 
White to Off-White
Water Solubility 
Soluble in water 20°C, 1000g/L.
Sensitive 
Hygroscopic
Merck 
14,412
CAS DataBase Reference
6011-14-9(CAS DataBase Reference)
EPA Substance Registry System
Aminoacetonitrile hydrochloride (6011-14-9)
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Safety

Risk Statements 
20/21/22-36/37/38-25
Safety Statements 
22-36/37-45-26
RIDADR 
3439
TSCA 
Yes
HazardClass 
6.1
PackingGroup 
III
HS Code 
29269090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P309IF exposed or if you feel unwell:

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
R288616
Product name
AMINOACETONITRILE HYDROCHLORIDE
Purity
AldrichCPR
Packaging
50MG
Price
$179
Updated
2024/03/01
Alfa Aesar
Product number
041984
Product name
Aminoacetonitrile hydrochloride, 98+%
Packaging
25g
Price
$82.5
Updated
2024/03/01
TRC
Product number
A580055
Product name
AminoacetonitrileHydrochloride
Packaging
10g
Price
$50
Updated
2021/12/16
Oakwood
Product number
079136
Product name
Aminoacetonitrile hydrochloride
Packaging
100g
Price
$55
Updated
2021/12/16
Oakwood
Product number
079136
Product name
Aminoacetonitrile hydrochloride
Packaging
1g
Price
$9
Updated
2021/12/16
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Aminoacetonitrile hydrochloride Chemical Properties,Usage,Production

Chemical Properties

White to light brown solid

Uses

Used as pharmaceutical intermediates, organic synthetic raw material transportation.

Application

Aminoacetonitrile is a useful synthetic intermediate. It is a reagent used to synthesize dipeptide nitriles as reversible and potent cathepsin S inhibitors. It can also used to prepare substituted cyclic ureas as possible HIV protease inhibitors.

Preparation

Synthesis of Aminoacetonitrile Hydrochloride by Reaction of Aminoacetonitrile with Hydrogen Chloride in Methanol: mixing the aminoacetonitrile with hydrogen chloride methanol solution, reacting at 45-50°C for 1-2 hours, cooling to below 5°C, filtering, and centrifugalizing to obtain the aminoacetonitrile hydrochloride, wherein in the hydrogen chloride methanol solution, the content of hydrogen chloride is 30-50 wt%, and the water content is less than or equal to 1%.
Preparation method of aminoacetonitrile hydrochloride

Safety Profile

An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and HCl.

Purification Methods

The salt recrystallises from dilute EtOH as hygroscopic leaflets. It is best to crystallise it from absolute EtOH/Et2O (1:1) and then recrystallise it from absolute EtOH. The melting point recorded ranges from 144o to 174o. The free base has b 58o/15mm with partial decomposition. [Klages J Prakt Chem [2] 65 189 1902, Mange J Am Chem Soc 56 2197 1934, Goldberg & Kelly J Chem Soc 1371 1947, Beilstein 4 H 344, 4 I 468, 4 II 783, 4 III 1120, 4 IV 2363.]

Aminoacetonitrile hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Aminoacetonitrile hydrochloride Suppliers

Shanghai Huichu Chemical Technology Co., Ltd
Tel
021-57188992 13917817467
Fax
021-5718892
Email
190994148@qq.com
Country
China
ProdList
59
Advantage
58
Mountainous Chemical Co.,Ltd
Tel
0523-87306168 18352621837
Fax
+86-523-87306528
Email
sales@mountainouschem.com
Country
China
ProdList
20
Advantage
58
Hubei Zhonglong Kangsheng Fine Chemical Co., Ltd.
Tel
15926260361
Fax
QQ:1930063008
Email
1930063008@qq.com
Country
China
ProdList
5094
Advantage
58
Shandong Dexin Fine Chemical Co. LTD
Tel
13475558980 13475558980
Email
644535754@qq.com
Country
China
ProdList
299
Advantage
58
Jinan Yunding Biotechnology Co., Ltd
Tel
15662712965
Email
1013429786@qq.com
Country
China
ProdList
22
Advantage
58
Changzhou jinhan pharmaceutical technology co., LTD
Tel
13917833665
Email
lyg@world-goldpharma.com
Country
China
ProdList
144
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
Advantage
69
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
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View Lastest Price from Aminoacetonitrile hydrochloride manufacturers

Hebei Duling International Trade Co. LTD
Product
2-AminoacetonitrileHydrochloride 6011-14-9
Price
US $30.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100 tons
Release date
2022-10-18
Hebei Mojin Biotechnology Co., Ltd
Product
Aminoacetonitrile hydrochloride 6011-14-9
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-09-13
Hebei Guanlang Biotechnology Co,.LTD
Product
Aminoacetonitrile hydrochloride 6011-14-9
Price
US $5.00-2.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000kg
Release date
2023-05-08

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