Aminoacetonitrile hydrochloride

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Aminoacetonitrile hydrochloride

Product Name: Aminoacetonitrile hydrochloride
CAS No.: 6011-14-9
Chemical Name: Aminoacetonitrile hydrochloride
Synonyms: Glycinonitrile hydrochloride;e hydrochL;GlycinonitrileHCl;Aminoacetonitrile hy;AMINO ACETONITRILE HCL;Acetonitrile hydrochloride;Cyanomethylazanium chloride;Aminoacetonitrilhydrochlorid;AMINOACETONITRILE HYDROCHLORIDE;2-AminoacetonitrileHydrochloride
CBNumber: CB2181554
Molecular Formula: C2H5ClN2
Formula Weight: 92.53
MOL File: 6011-14-9.mol

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Aminoacetonitrile hydrochloride Property

Melting point:: 172-174°C
RTECS: MC1950000
storage temp.: Inert atmosphere,Room Temperature
solubility: Methanol (Slightly, Heated), Water
form: Powder
color: White to Off-White
Water Solubility: Soluble in water 20°C, 1000g/L.
Sensitive: Hygroscopic
Merck: 14,412
CAS DataBase Reference: 6011-14-9(CAS DataBase Reference)
EPA Substance Registry System: Aminoacetonitrile hydrochloride (6011-14-9)

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Safety

Risk Statements: 20/21/22-36/37/38-25
Safety Statements: 22-36/37-45-26
RIDADR: 3439
TSCA: Yes
HazardClass: 6.1
PackingGroup: III
HS Code: 29269090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P309IF exposed or if you feel unwell:

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: R288616
Product name: AMINOACETONITRILE HYDROCHLORIDE
Purity: AldrichCPR
Packaging: 50MG
Price: $179
Updated: 2024/03/01

Alfa Aesar

Product number: 041984
Product name: Aminoacetonitrile hydrochloride, 98+%
Packaging: 25g
Price: $82.5
Updated: 2024/03/01

TRC

Product number: A580055
Product name: AminoacetonitrileHydrochloride
Packaging: 10g
Price: $50
Updated: 2021/12/16

Oakwood

Product number: 079136
Product name: Aminoacetonitrile hydrochloride
Packaging: 1g
Price: $9
Updated: 2021/12/16

Oakwood

Product number: 079136
Product name: Aminoacetonitrile hydrochloride
Packaging: 5g
Price: $10
Updated: 2021/12/16

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Aminoacetonitrile hydrochloride Chemical Properties,Usage,Production

Chemical Properties

White to light brown solid

Uses

Used as pharmaceutical intermediates, organic synthetic raw material transportation.

Application

Aminoacetonitrile is a useful synthetic intermediate. It is a reagent used to synthesize dipeptide nitriles as reversible and potent cathepsin S inhibitors. It can also used to prepare substituted cyclic ureas as possible HIV protease inhibitors.

Preparation

Synthesis of Aminoacetonitrile Hydrochloride by Reaction of Aminoacetonitrile with Hydrogen Chloride in Methanol: mixing the aminoacetonitrile with hydrogen chloride methanol solution, reacting at 45-50°C for 1-2 hours, cooling to below 5°C, filtering, and centrifugalizing to obtain the aminoacetonitrile hydrochloride, wherein in the hydrogen chloride methanol solution, the content of hydrogen chloride is 30-50 wt%, and the water content is less than or equal to 1%.
Preparation method of aminoacetonitrile hydrochloride

Safety Profile

An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and HCl.

Purification Methods

The salt recrystallises from dilute EtOH as hygroscopic leaflets. It is best to crystallise it from absolute EtOH/Et2O (1:1) and then recrystallise it from absolute EtOH. The melting point recorded ranges from 144o to 174o. The free base has b 58o/15mm with partial decomposition. [Klages J Prakt Chem [2] 65 189 1902, Mange J Am Chem Soc 56 2197 1934, Goldberg & Kelly J Chem Soc 1371 1947, Beilstein 4 H 344, 4 I 468, 4 II 783, 4 III 1120, 4 IV 2363.]

Aminoacetonitrile hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

1-AMINOCYCLOPROPANECARBONITRILE 2-AMINOPENT-4-YNENITRILE

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View Lastest Price from Aminoacetonitrile hydrochloride manufacturers

Henan Fengda Chemical Co., Ltd

Product: Aminoacetonitrile hydrochloride 6011-14-9
Price: US $5.00-0.10/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-04-15

Hebei Duling International Trade Co. LTD

Product: 2-AminoacetonitrileHydrochloride 6011-14-9
Price: US $30.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100 tons
Release date: 2022-10-18

Hebei Mojin Biotechnology Co., Ltd

Product: Aminoacetonitrile hydrochloride 6011-14-9
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50000KG/month
Release date: 2023-09-13

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Aminoacetonitrilhydrochlorid

6011-14-9

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H2NCH2CNHCl

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Pharmaceutical Intermediates

straight chain compounds