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Methylaminoacetonitrile hydrochloride

Product Name
Methylaminoacetonitrile hydrochloride
CAS No.
25808-30-4
Chemical Name
Methylaminoacetonitrile hydrochloride
Synonyms
SARCOSINITRILE;JACS-25808-30-4;Methylaminoacetonitr;METHYLAMINOACETONITRILE HCL;SARCOSINITRILE HYDROCHLORIDE;N-METHYL AMINOACETONITRILE HCL;SARCOSINE NITRILE HYDROCHLORIDE;cyanomethyl(methyl)ammonium chloride;(methylamino)acetonitrilhydrochlorid;METHYLAMINOACETONITRILE HYDROCHLORIDE
CBNumber
CB7722259
Molecular Formula
C3H7ClN2
Formula Weight
106.55
MOL File
25808-30-4.mol
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Methylaminoacetonitrile hydrochloride Property

Melting point:
103-106 °C(lit.)
storage temp. 
Inert atmosphere,Room Temperature
Appearance
White to off-white Solid
BRN 
3908975
InChI
1S/C3H6N2.ClH/c1-5-3-2-4;/h5H,3H2,1H3;1H
InChIKey
DFKBQHBEROHUNF-UHFFFAOYSA-N
SMILES
Cl.CNCC#N
CAS DataBase Reference
25808-30-4(CAS DataBase Reference)
EPA Substance Registry System
Acetonitrile, (methylamino)-, monohydrochloride (25808-30-4)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
TSCA 
TSCA listed
HS Code 
29269090
Storage Class
11 - Combustible Solids
Hazard Classifications
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
M28103
Product name
Methylaminoacetonitrile hydrochloride
Purity
98%
Packaging
25g
Price
$137
Updated
2022/05/15
Sigma-Aldrich
Product number
M28103
Product name
Methylaminoacetonitrile hydrochloride
Purity
98%
Packaging
100g
Price
$409
Updated
2022/05/15
TRC
Product number
M328723
Product name
Methylaminoacetonitrile hydrochloride
Packaging
5g
Price
$75
Updated
2021/12/16
TRC
Product number
M328723
Product name
Methylaminoacetonitrile hydrochloride
Packaging
500mg
Price
$45
Updated
2021/12/16
Matrix Scientific
Product number
075257
Product name
Methylaminoacetonitrile hydrochloride
Purity
95+%
Packaging
100g
Price
$58
Updated
2021/12/16
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Methylaminoacetonitrile hydrochloride Chemical Properties,Usage,Production

Chemical Properties

Yellow crystal

Uses

Methylaminoacetonitrile hydrochloride can be used as an intermediate in pharmaceutical and chemical synthesis. It is the raw material for the preparation of tadalafil. Approved by the FDA in 2003, tadalafil was marketed in the United States as a drug for the treatment of erectile dysfunction in men.

Synthesis

A method of preparing methylaminoacetonitrile hydrochloride, comprising: (1) reacting methylamine hydrochloride, sodium cyanide and formaldehyde as reaction raw materials to form methylaminoacetonitrile in the presence of a catalyst; and (2) reacting said methylaminoacetonitrile with hydrochloric acid to form said methylaminoacetonitrile hydrochloride, and in step (1) the reaction is carried out at below 0?? C. using 3-mercaptopropionic acid as a catalyst, and the amount of catalyst is from 0.9 to 1.1 times.

Methylaminoacetonitrile hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Methylaminoacetonitrile hydrochloride Suppliers

J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3572
Advantage
66
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13522913783
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
11777
Advantage
60
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11032
Advantage
64
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9892
Advantage
59
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527621225
Email
1791901229@qq.com
Country
China
ProdList
6908
Advantage
52
Shandong Xiya Chemical Co., Ltd
Tel
13355009207 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18729
Advantage
57
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12984
Advantage
57
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View Lastest Price from Methylaminoacetonitrile hydrochloride manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
Methylaminoacetonitrile hydrochloride 25808-30-4
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
10000KGS
Release date
2025-05-26
Zhuozhou Wenxi import and Export Co., Ltd
Product
2-(methylamino)acetonitrile,hydrochloride 25808-30-4
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
2-(methylamino)acetonitrile,hydrochloride 25808-30-4
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09

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