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PROHEXADIONE

Product Name
PROHEXADIONE
CAS No.
88805-35-0
Chemical Name
PROHEXADIONE
Synonyms
PROHEXADIONE;PROHEXADIONE STANDARD;Prohexadione Solution, 1000ppm;Cyclohexanecarboxylic acid, 3,5-dioxo-4-(1-oxopropyl)-
CBNumber
CB1365986
Molecular Formula
C10H12O5
Formula Weight
212.2
MOL File
88805-35-0.mol
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PROHEXADIONE Property

Melting point:
98-99°
Boiling point:
454.9±45.0 °C(Predicted)
Density 
1.330±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Chloroform: soluble
form 
A solid
pka
2.66±0.25(Predicted)
LogP
-1.098 (est)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
PST0000401
Product name
PROHEXADIONE
Purity
98.00%
Packaging
100MG
Price
$1120.35
Updated
2021/12/16
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PROHEXADIONE Chemical Properties,Usage,Production

Uses

Prohexadione (BX-112 free acid) is a plant growth regulator. Prohexadione inhibits gibberellin biosynthesis of plants[1][2].

Definition

ChEBI: Prohexadione is a 4-oxo monocarboxylic acid that is cyclohexanecarboxylic acid which is substituted by oxo groups at positions 3 and 5, and by a propanoyl group at position 4. A plant growth regulator, it is used (commonly as the corresponding calcium salt, known as prohexadione-calcium) as an anti-lodging agent in small-grain cereals. It has a role as an agrochemical, a plant growth regulator and a gibberellin biosynthesis inhibitor. It is a 4-oxo monocarboxylic acid and a beta-triketone. It is a conjugate acid of a prohexadione(2-).

Enzyme inhibitor

This plant growth regulator (FWfree-acid = 178.19 g/mol), also named 3- hydroxy-5-oxo-4-propionylcyclohex-3-ene-1-carboxylic acid, inhibits the biosynthesis of growth active gibberellins (GAs), thereby reducing longitudinal shoot growth. Prohexadione resembles 2-oxoglutaric acid, the co-substrate the dioxygenases that catalyze hydroxylation steps in late stages of GA biosynthesis. Its primary target of is 3b hydroxylation, thereby reducing levels of GA1 (the highly active form) and bringing about theaccumulation of its immediate precursor (inactive). Targets: flavanone 3-dioxygenase flavonol synthase; and gibberellin biosynthesis.

References

[1] Paulson GS, et al. Effect of a plant growth regulator prohexadione-calcium on insect pests of apple and pear. J Econ Entomol. 2005 Apr;98(2):423-31. DOI:10.1093/jee/98.2.423
[2] Vavilala DT, et al. Prohexadione, a plant growth regulator, inhibits histone lysine demethylases and modulates epigenetics. Toxicol Rep. 2014 Nov 4;1:1152-1161.
[3] Feng N, et al. Prohexadione-calcium alleviates saline-alkali stress in soybean seedlings by improving the photosynthesis and up-regulating antioxidant defense. Ecotoxicol Environ Saf. 2021 Sep 1;220:112369. DOI:10.1016/j.ecoenv.2021.112369
[4] McGrath MJ, et al. Evidence that prohexadione-calcium induces structural resistance to fire blight infection. Phytopathology. 2009 May;99(5):591-6. DOI:10.1094/PHYTO-99-5-0591

PROHEXADIONE Preparation Products And Raw materials

Raw materials

Preparation Products

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PROHEXADIONE Suppliers

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