L-Histidine hydrochloride monohydrate

Product Name: L-Histidine hydrochloride monohydrate
CAS No.: 5934-29-2
Chemical Name: L-Histidine hydrochloride monohydrate
Synonyms: 15N3, 98%);L-HIS HCL H2O;L-His.H2o.HCl;Histidine (H);HISTIDINE HCL;H-His-OH¤HCl¤H;L-HISTIDINEHCL;H-HIS-OH HCL H2O;L-His-OH·HCl·H2O;HISTIDINE HCL H2O
CBNumber: CB1369616
Molecular Formula: C6H12ClN3O3
Formula Weight: 209.63
MOL File: 5934-29-2.mol

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L-Histidine hydrochloride monohydrate Property

Melting point:: 254 °C (dec.)(lit.)
alpha: 9.9 º (c=11, 6 N HCl)
Density: 1.49 g/cm3
vapor pressure: <1 hPa (20 °C)
storage temp.: Store below +30°C.
solubility: H₂O: 100 mg/mL
form: Solid
color: White
Odor: odorless
PH: 3.5-4.5 (100g/l, H2O, 20℃)
PH Range: 3 - 4 at 105 g/l at 25 °C
optical activity: [α]20/D +9.5±0.5°, c = 5% in 5 M HCl
Water Solubility: 169.9 g/L (20 ºC)
Merck: 14,4720
BRN: 4168261
InChIKey: CMXXUDSWGMGYLZ-XRIGFGBMSA-N
LogP: -3.32 at 25℃
CAS DataBase Reference: 5934-29-2(CAS DataBase Reference)

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Safety

Hazard Codes: Xn
Risk Statements: 22-36/37/38
Safety Statements: 22-24/25-36/37-26
WGK Germany: 3
RTECS: MS3119000
F: 10
TSCA: Yes
HS Code: 29332990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: H5659
Product name: L-Histidine monohydrochloride monohydrate
Purity: from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-101.0%
Packaging: 25G
Price: $52.3
Updated: 2024/03/01

Sigma-Aldrich

Product number: H5659
Product name: L-Histidine monohydrochloride monohydrate
Purity: from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-101.0%
Packaging: 100G
Price: $134
Updated: 2024/03/01

Sigma-Aldrich

Product number: H5659
Product name: L-Histidine monohydrochloride monohydrate
Purity: from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-101.0%
Packaging: 1KG
Price: $819
Updated: 2024/03/01

Sigma-Aldrich

Product number: 8.16005
Product name: (S)-(+)-Histidine hydrochloride monohydrate
Purity: for synthesis
Packaging: 25g
Price: $38.1
Updated: 2024/03/01

Sigma-Aldrich

Product number: 53370
Product name: L-Histidine monohydrochloride monohydrate
Purity: ≥99.0% (AT)
Packaging: 25g
Price: $32.2
Updated: 2024/03/01

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L-Histidine hydrochloride monohydrate Chemical Properties,Usage,Production

Chemical Properties

white crystals or cryst. or granular powder

Uses

L-Histidine is used in cell culture media formulations used in biomanufacturing. L-Histidine has been used to study cultures of the human T-lymphoblastic leukemia cell line MOLT-4 to study modulation of apoptosis.

Uses

L-Histidine monohydrochloride, non-animal, is used in cell culture media formulations used in biomanufacturing. The use of non-animal-sourced L-Histidine and other components avoids the risk of contaminating bioproducts with adventitious viruses.

Uses

L-Histidine Hydrochloride Monohydrate can be used as AhR activators to treat gluten-induced gastrointestinal diseases. It can also be used for hair coloring method.

General Description

Chemicals play an important role in the stabilization of a biologic drug during its manufacturing and formulation process – for instance, by preventing aggregation. We offer a wide range of high-quality stabilizers, buffers and salts to successfully purify and formulate your biomolecules. Specifically developed for high-risk applications, they are low in bioburden and endotoxins.
As part of our Emprove^? Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^? portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Biochem/physiol Actions

L-Histidine is biosynthesized from ATP, 5-phosphoribosyl-1-pyrophosphate (PRPP), and glutamine. This essential amino acid can be degraded to glutamate by histidiase, urocanase and imidazolonepropionase; it is also the precursor of histamine by action of histidine decarboxylase.

Purification Methods

Crystallise the monohydrochloride from aqueous EtOH or 60% aqueous EtOH (m 259odec). Alternatively dissolve 10g in 50mL of H2O, decolourise with Norite, filter, evaporate it in a vacuum to a syrup, cool to room temperature, add 95% EtOH with stirring until slightly turbid, scratch the sides of the vessel until crystals form, then add slowly 40mL of EtOH and keep at 0o overnight, filter the solid off, wash it several times with EtOH and dry it in a vacuum. [Cox J Biol Chem 78 475 1929, Cox et al. J Biol Chem 81 73 1929, Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 pp 1972, 2098 1961, Beilstein 25 II 407, 25 III/IV 4346.]

L-Histidine hydrochloride monohydrate Preparation Products And Raw materials

Raw materials

HEMOGLOBIN Soy bean Isoflavone Isoflavone 10-40% L-Lysine Hydrolyzate Ion exchange resin column

Preparation Products

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L-Histidine hydrochloride monohydrate Suppliers

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View Lastest Price from L-Histidine hydrochloride monohydrate manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: L-Histidine hydrochloride monohydrate 5934-29-2
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 5000kg/month
Release date: 2021-08-16

airuikechemical co., ltd.

Product: l-histidine hydrochloride monohydrate 5934-29-2
Price: US $0.00-0.00/Kg
Min. Order: 1Kg
Purity: 99.9%
Supply Ability: 200tons
Release date: 2024-04-07

Hebei Mojin Biotechnology Co., Ltd

Product: L-Histidine hydrochloride monohydrate 5934-29-2
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50000KG/month
Release date: 2024-10-12

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