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DFMO

Product Name
DFMO
CAS No.
66640-93-5
Chemical Name
DFMO
Synonyms
DFMO;L-DFMO;L-RMI71782;EFLORNITINE;L-Eflornithine;H-DL-(F2ME)ORN-OH;DIFLUOROMETHYLORNITHINE;L-α-difluoromethylornithine;L-α-difluoromethylornithine;L Eflornithine,LEflornithine
CBNumber
CB1373228
Molecular Formula
C6H12F2N2O2
Formula Weight
182.17
MOL File
66640-93-5.mol
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DFMO Property

Boiling point:
347.0±42.0 °C(Predicted)
Density 
1.293±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
pka
1.22±0.44(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

AHH
Product number
MT-50140
Product name
Difluoromethylornithine
Purity
98%
Packaging
1g
Price
$310
Updated
2021/12/16
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DFMO Chemical Properties,Usage,Production

Biological Activity

L-Eflornithine (L-DFMO) is the enantiomer of Eflornithine. L-Eflornithine is an irreversible ornithine decarboxylase (ODC) inhibitor with KD of 1.3±0.3 μM and Kinact of 0.15±0.03 min-1.

in vivo

The more potent L-Eflornithine is present at much lower concentrations in both plasma and cerebrospinal fluid (CSF) than those of the D-Eflornithine. The plasma concentrations of L-Eflornithine are on average 52% of the D -enantiomer concentrations. The typical oral clearances of L-Eflornithine and D-eflornithine are 17.4 and 8.23 liters/h, respectively.

target

KD: 1.3±0.3 μM (Ornithine decarboxylase, ODC)

DFMO Preparation Products And Raw materials

Raw materials

Preparation Products

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DFMO Suppliers

TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
19892
Advantage
58
Sanover (Xiamen) Technology Co., Ltd
Tel
059265188632; 13876246362
Fax
QQ : 422165847
Email
422165847@qq.com
Country
China
ProdList
510
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24131
Advantage
58

66640-93-5, DFMORelated Search:


  • ALPHA-DIFLUORO-ME-DL-ORNITHINE
  • ALPHA-DIFLUOROMETHYL-DL-ORNITHINE
  • L-alpha-Difluoromethylornithine
  • DFMO
  • EFLORNITINE
  • DL-ALPHA-DIFLUOROMETHYLORNITHINE
  • DIFLUOROMETHYLORNITHINE
  • H-DL-(F2ME)ORN-OH
  • H-DL-(ALPHA-DIFLUOROMETHYL)ORN-OH
  • H-ALPHA-DIFLUORO-ME-DL-ORN-OH
  • L-Eflornithine
  • L-DFMO
  • L-RMI71782
  • L-α-difluoromethylornithine
  • L-Ornithine, 2-(difluoromethyl)-
  • L-α-difluoromethylornithine
  • L Eflornithine,LEflornithine
  • 66640-93-5
  • Angiogenesis
  • BioChemical
  • Cancer Research
  • Angiogenesis Inhibitors