ChemicalBook > CAS DataBase List > DFMO

DFMO

Product Name
DFMO
CAS No.
66640-93-5
Chemical Name
DFMO
Synonyms
DFMO;L-DFMO;L-RMI71782;EFLORNITINE;L-Eflornithine;H-DL-(F2ME)ORN-OH;DIFLUOROMETHYLORNITHINE;L-α-difluoromethylornithine;L-α-difluoromethylornithine;L Eflornithine,LEflornithine
CBNumber
CB1373228
Molecular Formula
C6H12F2N2O2
Formula Weight
182.17
MOL File
66640-93-5.mol
More
Less

DFMO Property

Boiling point:
347.0±42.0 °C(Predicted)
Density 
1.293±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
pka
1.22±0.44(Predicted)
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

AHH
Product number
MT-50140
Product name
Difluoromethylornithine
Purity
98%
Packaging
1g
Price
$310
Updated
2021/12/16
More
Less

DFMO Chemical Properties,Usage,Production

Biological Activity

L-Eflornithine (L-DFMO) is the enantiomer of Eflornithine. L-Eflornithine is an irreversible ornithine decarboxylase (ODC) inhibitor with KD of 1.3±0.3 μM and Kinact of 0.15±0.03 min-1.

in vivo

The more potent L-Eflornithine is present at much lower concentrations in both plasma and cerebrospinal fluid (CSF) than those of the D-Eflornithine. The plasma concentrations of L-Eflornithine are on average 52% of the D -enantiomer concentrations. The typical oral clearances of L-Eflornithine and D-eflornithine are 17.4 and 8.23 liters/h, respectively.

target

KD: 1.3±0.3 μM (Ornithine decarboxylase, ODC)

DFMO Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

DFMO Suppliers

TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32063
Advantage
58
Sanover (Xiamen) Technology Co., Ltd
Tel
059265188632; 13876246362
Fax
QQ : 422165847
Email
422165847@qq.com
Country
China
ProdList
509
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24648
Advantage
58
TargetMol Chemicals Inc.
Tel
+8613564774135
Email
zijue.cai@tsbiochem.com
Country
United States
ProdList
19863
Advantage
58
TargetMol Chemicals Inc.
Tel
Email
support@targetmol.com
Country
United States
ProdList
38463
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
52925
Advantage
58

66640-93-5, DFMORelated Search:


  • ALPHA-DIFLUORO-ME-DL-ORNITHINE
  • ALPHA-DIFLUOROMETHYL-DL-ORNITHINE
  • L-alpha-Difluoromethylornithine
  • DFMO
  • EFLORNITINE
  • DL-ALPHA-DIFLUOROMETHYLORNITHINE
  • DIFLUOROMETHYLORNITHINE
  • H-DL-(F2ME)ORN-OH
  • H-DL-(ALPHA-DIFLUOROMETHYL)ORN-OH
  • H-ALPHA-DIFLUORO-ME-DL-ORN-OH
  • L-Eflornithine
  • L-DFMO
  • L-RMI71782
  • L-α-difluoromethylornithine
  • L-Ornithine, 2-(difluoromethyl)-
  • L-α-difluoromethylornithine
  • L Eflornithine,LEflornithine
  • 66640-93-5
  • Angiogenesis
  • BioChemical
  • Cancer Research
  • Angiogenesis Inhibitors