PIPERAZINE ADIPATE Property

Melting point:

256-257°

Boiling point:

374.44°C (rough estimate)

Density 

1.1633 (rough estimate)

vapor pressure 

2.8hPa

refractive index 

1.4710 (estimate)

storage temp. 

Store at -20°C

solubility 

571.42mg/L in organic solvents at 20 ℃

pka

0[at 20 ℃]

color 

White to Almost white

Odor

at 100.00?%. odorless

Water Solubility 

almost transparency

Merck 

14,7465

Stability:

Stable. Combustible. Incompatible with strong oxidizing agents. May be light-sensitive.

LogP

-0.522 at 28℃

CAS DataBase Reference

142-88-1(CAS DataBase Reference)

EPA Substance Registry System

Piperazine adipate (1:1) (142-88-1)

Safety

RIDADR 

UN 2579 8 / PGIII

RTECS 

MO1955000

HS Code 

2933599550

Toxicity

LD50 in mice, rats (g/kg): 11.4, 7.9 orally (Cross)

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

H317May cause an allergic skin reaction

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P272Contaminated work clothing should not be allowed out of the workplace.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P285In case of inadequate ventilation wear respiratory protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P304+P341IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

P342+P311IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.

P363Wash contaminated clothing before reuse.

P405Store locked up.

P501Dispose of contents/container to..…

PIPERAZINE ADIPATE Chemical Properties,Usage,Production

Chemical Properties

white crystals or powder

Uses

It is used as an anthelmintic for humans and farm animals against intestinal roundworms and pinworms infection

Uses

Piperazine Adipate is used as an anthelmintic agent. Derivatives of piperazine are widely used in the pharmaceutical, biomedical and chemical fields. Piperazine derivatives are known to have high antiserotonin potency, antimicrobial activity, and potential anticancer activity in humans.

Definition

ChEBI: Piperazine adipate is a piperazinium salt obtained by combining equimolar amounts of piperazine and adipic acid. It has a role as an anthelminthic drug and an antinematodal drug. It contains an adipate(2-) and a piperazinium(2+).

General Description

Odorless white crystalline powder or solid. Slightly acid taste. Melting point 256-257°C. Dissolves slowly. pH (0.2-0.01 molar aqueous solutions) 5.45. pH (5% solution) 5 - 6.

Air & Water Reactions

Water soluble.

Reactivity Profile

PIPERAZINE ADIPATE gives weakly acidic aqueous solutions. Can serve as both an oxidizing agent and as a reducing agent.

Fire Hazard

Flash point data for PIPERAZINE ADIPATE are not available; however PIPERAZINE ADIPATE is probably combustible.

Flammability and Explosibility

Non flammable