8-Chloroquinoline
- Product Name
- 8-Chloroquinoline
- CAS No.
- 611-33-6
- Chemical Name
- 8-Chloroquinoline
- Synonyms
- 8-chloro-quinolin;8-CHLOROQUINOLINE;8-Chloroquinoline>Quinoline, 8-chloro-;8-Chloroquinoline ,99%;8-Chloroquinoline, 98%+;8-Chloro-1-azanaphthalene;8-Chloroquinoline ISO 9001：2015 REACH
- CBNumber
- CB1376643
- Molecular Formula
- C9H6ClN
- Formula Weight
- 163.6
- MOL File
- 611-33-6.mol
8-Chloroquinoline Property
- Melting point:
- -20 °C
- Boiling point:
- 288.5 °C
- Density
- 1.28
- refractive index
- 1.6450-1.6480
- Flash point:
- >110℃
- storage temp.
- Inert atmosphere,Room Temperature
- pka
- 2.33±0.17(Predicted)
- form
- Liquid
- Specific Gravity
- 1.27
- color
- Clear yellow to brown
- Water Solubility
- SOLUBLE
- CAS DataBase Reference
- 611-33-6(CAS DataBase Reference)
- NIST Chemistry Reference
- Quinoline, 8-chloro-(611-33-6)
- EPA Substance Registry System
- Quinoline, 8-chloro- (611-33-6)
Safety
- Hazard Codes
- Xi,T
- Risk Statements
- 36/37/38-25
- Safety Statements
- 37/39-26-36/37/39-45
- RIDADR
- UN 2811 6.1 / PGIII
- HazardClass
- IRRITANT
- HS Code
- 29334900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- CDS004725
- Product name
- 8-Chloroquinoline
- Purity
- AldrichCPR
- Packaging
- 100mg
- Price
- $73.1
- Updated
- 2025/07/31
- Product number
- C0284
- Product name
- 8-Chloroquinoline
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $136
- Updated
- 2025/07/31
- Product number
- C0284
- Product name
- 8-Chloroquinoline
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $481
- Updated
- 2025/07/31
- Product number
- R008
- Product name
- 8-Chloroquinoline
- Packaging
- 1g
- Price
- $14
- Updated
- 2021/12/16
- Product number
- FC35037
- Product name
- 8-chloroquinoline
- Packaging
- 2g
- Price
- $45
- Updated
- 2021/12/16
8-Chloroquinoline Chemical Properties,Usage,Production
Chemical Properties
CLEAR YELLOW TO BROWN LIQUID
Definition
ChEBI: 8-chloroquinoline is a member of quinolines and an organochlorine compound.
Synthesis Reference(s)
The Journal of Organic Chemistry, 52, p. 1673, 1987 DOI: 10.1021/jo00385a006
Synthesis
4470-83-1
611-33-6
General procedure for the synthesis of 8-chloroquinoline from 2,8-dichloroquinoline: PdCl2 (dppf), PdCl2 (tbpf), or (A.caPhos) PdCl2 was used as catalyst. First, the halogenated heterocyclic compound (0.66 mmol) was dissolved in anhydrous THF (13.2 mL) and degassed by drumming argon for several minutes. Subsequently, PdCl2 (dppf) (27.0 mg, 0.033 mmol, 5.0 mol%), TMEDA (0.130 g, 1.12 mmol, 1.7 equiv) and NaBH4 (42.4 mg, 1.12 mmol, 1.7 equiv) were added sequentially. The reaction mixture was stirred under argon protection at room temperature for an appropriate time and then post-treated in the usual way.
Purification Methods
Purify it by crystallisation of its ZnCl2 complex (m 228o) from aqueous EtOH. [Beilstein 20 III/IV 3381, 20/7 V 315.]
References
[1] Journal of Molecular Catalysis A: Chemical, 2014, vol. 393, p. 191 - 209
8-Chloroquinoline Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 8-Chloroquinoline manufacturers
- Product
- 8-Chloroquinoline 611-33-6
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-12
- Product
- 8-Chloroquinoline 611-33-6
- Price
- US $230.00/g
- Min. Order
- 1g
- Purity
- 98
- Supply Ability
- 500 Kg
- Release date
- 2024-02-19
- Product
- 8-Chloroquinoline 611-33-6
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20 tons
- Release date
- 2021-10-13