4-CHLORO-6-HYDROXYQUINAZOLINE

Product Name: 4-CHLORO-6-HYDROXYQUINAZOLINE
CAS No.: 848438-50-6
Chemical Name: 4-CHLORO-6-HYDROXYQUINAZOLINE
Synonyms: 183836;4-CHLOROQUINAZOLIN-6-OL;6-Quinazolinol, 4-chloro-;4-CHLORO-6-HYDROXYQUINAZOLINE
CBNumber: CB1378384
Molecular Formula: C8H5ClN2O
Formula Weight: 180.59
MOL File: 848438-50-6.mol

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4-CHLORO-6-HYDROXYQUINAZOLINE Property

storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
Appearance: Off-white to light yellow Solid

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: C895668
Product name: 4-Chloroquinazolin-6-ol
Packaging: 50mg
Price: $220
Updated: 2021/12/16

AK Scientific

Product number: 2702AL
Product name: 4-Chloroquinazolin-6-ol
Packaging: 1g
Price: $990
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0104895
Product name: 4-CHLOROQUINAZOLIN-6-OL
Purity: 95.00%
Packaging: 5MG
Price: $497.48
Updated: 2021/12/16

Chemenu

Product number: CM217289
Product name: 4-Chloroquinazolin-6-ol
Purity: 95%
Packaging: 1g
Price: $655
Updated: 2021/12/16

Crysdot

Product number: CD11046996
Product name: 4-Chloroquinazolin-6-ol
Purity: 95+%
Packaging: 1g
Price: $691
Updated: 2021/12/16

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4-CHLORO-6-HYDROXYQUINAZOLINE Chemical Properties,Usage,Production

Synthesis

179246-11-8

848438-50-6

Step E: Preparation of 4-chloroquinazolin-6-ol: 4-chloroquinazolin-6-yl acetate (10.0 g, 44.9 mmol) was dissolved in a methanol solution of ammonia (200 mL, 7N), and the reaction was stirred for 1 hour at room temperature. Upon completion of the reaction, the reaction mixture was concentrated under reduced pressure to about 3 mL, and the residue was ground with ether to precipitate a tan solid which was collected by filtration and dried to give 4-chloroquinazolin-6-ol (6.50 g, 80% yield).

References

[1] Patent: EP2090575, 2009, A1. Location in patent: Page/Page column 62
[2] Patent: WO2005/26151, 2005, A1. Location in patent: Page/Page column 113
[3] Patent: WO2011/130459, 2011, A1. Location in patent: Page/Page column 60
[4] European Journal of Medicinal Chemistry, 2018, vol. 147, p. 130 - 149

4-CHLORO-6-HYDROXYQUINAZOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-CHLORO-6-HYDROXYQUINAZOLINE Suppliers

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848438-50-6, 4-CHLORO-6-HYDROXYQUINAZOLINERelated Search:

7-HYDROXY-1H-QUINAZOLIN-4-ONE 2,4-Dichloro-6,7-dimethoxyquinazoline 4-Chloro-6,7-bis(2-methoxyethoxy)quinazoline 7-Benzyloxy-4-chloro-6-methoxyquinazoline 6-METHOXY-QUINAZOLIN-4-YLAMINE 4-Chloro-6,7-dimethoxyquinazoline 4-Chloro-6-acetoxy-7-methoxyquinazoline hydrochloride 4-CHLORO-6-HYDROXYQUINAZOLINE 4-CHLORO-6-ETHOXY-QUINAZOLINE 4-CHLORO-7-FLUORO-6-METHOXY-QUINAZOLINE 4-CHLORO-6,7-DIMETHOXY-2-PHENYLQUINAZOLINE 6-ACETOXY-4-CHLOROQUINAZOLINE 4-CHLORO-6-(2-CHLORO-ETHOXY)-7-(2-METHOXY-ETHOXY)-QUINAZOLINE 4-CHLORO-7-(2-CHLORO-ETHOXY)-6-(2-METHOXY-ETHOXY)-QUINAZOLINE 7-ACETOXY-4-CHLORO-6-METHOXYQUINAZOLINE 2-AMINO-4-CHLORO-6,7-DIMETHOXYQUINAZOLINE 4-CHLORO-5,6,7-TRIMETHOXYQUINAZOLINE 4-CHLORO-6-HYDROXY-2-TRIFLUOROMETHYL-QUINAZOLINE

4-CHLORO-6-HYDROXYQUINAZOLINE

4-CHLOROQUINAZOLIN-6-OL

183836

6-Quinazolinol, 4-chloro-

848438-50-6