ChemicalBook > CAS DataBase List > N-(TERT-BUTOXYCARBONYL)-P-TOLUENESULFONAMIDE

N-(TERT-BUTOXYCARBONYL)-P-TOLUENESULFONAMIDE

Product Name: N-(TERT-BUTOXYCARBONYL)-P-TOLUENESULFONAMIDE
CAS No.: 18303-04-3
Chemical Name: N-(TERT-BUTOXYCARBONYL)-P-TOLUENESULFONAMIDE
Synonyms: tert-Butyl tosylcarbamate;TsNBoc;LABOTEST-BB LT00453242;N-Boc-toluenesulfonamide;N-BOC-P-TOLUENESULFONAMIDE;tert-Butyl N-tosylcarbamate;(tert-Butoxycarbonyl)tosylamine;tert-Butyl N-(p-tosyl)carbamate;N-Boc-4-methylbenzenesulfonamide;Tosylcarbamic acid tert-butyl ester
CBNumber: CB1380558
Molecular Formula: C12H17NO4S
Formula Weight: 271.33
MOL File: 18303-04-3.mol

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N-(TERT-BUTOXYCARBONYL)-P-TOLUENESULFONAMIDE Property

Melting point:: 121-123 °C(lit.)
Density: 1.201±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: chloroform: soluble25mg/mL, clear, colorless
form: powder to crystal
pka: 4.84±0.10(Predicted)
color: White to Almost white
InChI: InChI=1S/C12H17NO4S/c1-9-5-7-10(8-6-9)18(15,16)13-11(14)17-12(2,3)4/h5-8H,1-4H3,(H,13,14)
InChIKey: DUTLOVSBVBGNDM-UHFFFAOYSA-N
SMILES: C(OC(C)(C)C)(=O)NS(C1=CC=C(C)C=C1)(=O)=O
CAS DataBase Reference: 18303-04-3

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Safety

Safety Statements: 24/25
WGK Germany: 3
HS Code: 29350090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 363839
Product name: N-(tert-Butoxycarbonyl)-p-toluenesulfonamide
Packaging: 25g
Price: $120
Updated: 2025/07/31

Sigma-Aldrich

Product number: 363839
Product name: N-(tert-Butoxycarbonyl)-p-toluenesulfonamide
Packaging: 5g
Price: $55
Updated: 2023/06/20

TCI Chemical

Product number: B1648
Product name: N-(tert-Butoxycarbonyl)-p-toluenesulfonamide
Purity: >98.0%(T)
Packaging: 10g
Price: $69
Updated: 2025/07/31

TCI Chemical

Product number: B1648
Product name: N-(tert-Butoxycarbonyl)-p-toluenesulfonamide
Purity: >98.0%(T)
Packaging: 25g
Price: $129
Updated: 2025/07/31

TRC

Product number: B810040
Product name: N-(tert-Butoxycarbonyl)-p-toluenesulfonamide
Packaging: 500mg
Price: $65
Updated: 2021/12/16

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N-(TERT-BUTOXYCARBONYL)-P-TOLUENESULFONAMIDE Chemical Properties,Usage,Production

Description

N-(TERT-BUTOXYCARBONYL)-P-TOLUENESULFONAMIDE is an useful component in Mitsunobu reactions for the direct preparation of protected amines from alcohols.

Uses

N-(tert-Butoxycarbonyl)-p-toluenesulfonamide may be used in the preparation of enyne amide, precursor for Pauson-Khand reaction.

Synthesis Reference(s)

Tetrahedron Letters, 35, p. 379, 1994 DOI: 10.1016/0040-4039(94)85058-5

General Description

N-(tert-Butoxycarbonyl)-p-toluenesulfonamide is a N-substituted sulphonamide and its reaction with N-trityl L-serine esters under Mitsunobu reaction conditions is reported. It can be directly coupled with primary, secondary and allylic alcohols under Mitsunobu conditions to afford various sulfonyl-protected amines.

storage

N-(TERT-BUTOXYCARBONYL)-P-TOLUENESULFONAMIDE can be stored for extended periods of time in an amber bottle at rt.

N-(TERT-BUTOXYCARBONYL)-P-TOLUENESULFONAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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N-(TERT-BUTOXYCARBONYL)-P-TOLUENESULFONAMIDE Suppliers

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View Lastest Price from N-(TERT-BUTOXYCARBONYL)-P-TOLUENESULFONAMIDE manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: N-(TERT-BUTOXYCARBONYL)-P-TOLUENESULFONAMIDE 18303-04-3
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1ton
Release date: 2022-09-26

Career Henan Chemical Co

Product: N-(TERT-BUTOXYCARBONYL)-P-TOLUENESULFONAMIDE 18303-04-3
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 200kg
Release date: 2019-08-29

18303-04-3, N-(TERT-BUTOXYCARBONYL)-P-TOLUENESULFONAMIDERelated Search:

2-Azido-1,3-diMethyliMidazoliniuM Hexafluorophosphate Toluenesulfonamide N-(4-BROMO-2-BUTYNYL)-N-(TERT-BUTYLOXYCARBONYL)(4-METHYLPHENYL)SULFONAMIDE N-(PHENYLSULFONYL)-CARBAMIC ACID METHYL ESTER methyl tosylcarbamate Ethyl N-(4-methylphenyl)sulfonylcarbamate N-(TERT-BUTOXYCARBONYL)-P-TOLUENESULFONAMIDE

LABOTEST-BB LT00453242

N-(TERT-BUTOXYCARBONYL)-P-TOLUENESULFONAMIDE

N-BOC-P-TOLUENESULFONAMIDE

N-(tert-Butoxycarbonyl-p-tolunesulfonamide

(tert-Butoxycarbonyl)tosylamine

N-(p-Tolylsulfonyl)carbamic acid tert-butyl ester

N-Tosylcarbamic acid tert-butyl ester

Tosylcarbamic acid tert-butyl ester

TsNBoc

tert-butyl N-(4-methylphenyl)sulfonylcarbamate

N-Boc-toluenesulfonamide

tert-Butyl N-(p-tosyl)carbamate

tert-Butyl N-tosylcarbamate

tert-Butyl tosylcarbamate

N-(tert-Butoxycarbonyl)-p-toluenesulfonamide

N-Boc-4-methylbenzenesulfonamide

Carbamic acid,N-[(4-methylphenyl)sulfonyl]-, 1,1-dimethylethyl ester

N-Boc-p-toluenesulfonamide, 99%, for synthesis

N-(tert-Butoxycarbonyl)-p-toluenesulfonamide &gt

ert-butylN-(4-methylphenyl)sulfonylcarbamate

N-(TERT-BUTOXYCARBONYL)-P-TOLUENESULFONAMIDE ISO 9001：2015 REACH

N-(Tert-butoxycarbonyl)-P-toluenesulfonamide, 98+%

N-[(tert-butoxy)carbonyl]-4-methylbenzenesulfonamide

tert-butyl N-(p-tolylsulfonyl)carbamate

tert-Butyl [(4-methylphenyl)sulfonyl]carbamate

N-(tert-Butyloxycarbonyl)-p-toluenesulfonamide

18303-04-3

CH3C6H4SO2NHCO2CCH33

Nitrogen Compounds

Organic Building Blocks

Protected Amines

Amination

Building Blocks

Amination

Synthetic Organic Chemistry

Nitrogen Compounds

Organic Building Blocks

Protected Amines