ChemicalBook > CAS DataBase List > 1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol
1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol
- Product Name
- 1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol
- CAS No.
- 1472-62-4
- Chemical Name
- 1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol
- Synonyms
- (+/-)-N-methylcoclaurine;1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol;7-Isoquinolinol, 1,2,3,4-tetrahydro-1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-
- CBNumber
- CB13823814
- Molecular Formula
- C18H21NO3
- Formula Weight
- 299.36
- MOL File
- 1472-62-4.mol
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1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol Property
- Melting point:
- 138 °C
- Boiling point:
- 480.9±45.0 °C(Predicted)
- Density
- 1.214±0.06 g/cm3(Predicted)
- pka
- 10.00±0.15(Predicted)
- form
- Solid
- color
- Off-white to light yellow
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1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol Chemical Properties,Usage,Production
Uses
(±)-N-Methylcoclaurine is a selective α2-adrenoceptor antagonist[1].
References
[1] H H Pauli, et al. Molecular cloning and functional heterologous expression of two alleles encoding (S)-N-methylcoclaurine 3'-hydroxylase (CYP80B1), a new methyl jasmonate-inducible cytochrome P-450-dependent mono-oxygenase of benzylisoquinoline alkaloid biosynthesis. Plant J. 1998 Mar;13(6):793-801. DOI:10.1046/j.1365-313x.1998.00085.x
1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol Preparation Products And Raw materials
Raw materials
Preparation Products
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1472-62-4, 1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-olRelated Search:
Coclaurine
(-)-1,2,3,4-Tetrahydro-7,8-dimethoxy-1-[(4-methoxyphenyl)methyl]isoquinoline
(+)-S-N-Methylcoclaurine Hydrochloride
GS 389
N-Methylcoclaurine
6,7-Isoquinolinediol, 1,2,3,4-tetrahydro-1-[(4-methoxyphenyl)methyl]-
Demethyl-Coclaurine
1,2,3,4-Tetrahydro-6-methoxy-1-[(4-methoxyphenyl)methyl]-7-isoquinolinol
1,2,3,4-Tetrahydro-7-methoxy-1-[(4-methoxyphenyl)methyl]-6-isoquinolinol
N-nitroso Coclaurine