N-Methylcoclaurine

Product Name: N-Methylcoclaurine
CAS No.: 5096-70-8
Chemical Name: N-Methylcoclaurine
Synonyms: D-Methylcoclaurine;(-)-N-methylcoclaurine;(R)-N-Methylcoclaurine;(R)-(-)-N-Methylcoclaurine;D-Methylcoclaurine/（R）-N-Methylcoclaurine/D-(-)-N-Methylcoclaurine;7-Isoquinolinol, 1,2,3,4-tetrahydro-1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-, (1R)-
CBNumber: CB22725437
Molecular Formula: C18H21NO3
Formula Weight: 299.36
MOL File: 5096-70-8.mol

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N-Methylcoclaurine Property

Melting point:: 184-185℃
Boiling point:: 480.9±45.0 °C(Predicted)
Density: 1.214±0.06 g/cm3(Predicted)
pka: 10.00±0.15(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Methylcoclaurine Chemical Properties,Usage,Production

Uses

(-)-N-methylcoclaurine possesses melanogenesis inhibitory activity[1].

Definition

ChEBI: (R)-N-methylcoclaurine is the (R)-enantiomer of N-methylcoclaurine. It is a conjugate base of a (R)-N-methylcoclaurinium. It is an enantiomer of a (S)-N-methylcoclaurine.

References

[1] Toshio Morikawa, et al. Quantitative Determination of Alkaloids in Lotus Flower (Flower Buds of Nelumbo nucifera) and Their Melanogenesis Inhibitory Activity. Molecules. 2016 Jul 19;21(7):930. DOI:10.3390/molecules21070930

N-Methylcoclaurine Preparation Products And Raw materials

Raw materials

Preparation Products

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N-Methylcoclaurine Suppliers

China 33 United States 2 Global 35

Wuxi Zhongkun Biochemical Technology Co., Ltd.

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(R)-(-)-N-Methylcoclaurine

(R)-N-Methylcoclaurine

D-Methylcoclaurine

7-Isoquinolinol, 1,2,3,4-tetrahydro-1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-, (1R)-

(-)-N-methylcoclaurine

D-Methylcoclaurine/（R）-N-Methylcoclaurine/D-(-)-N-Methylcoclaurine

5096-70-8