trans-Cevimeline Hydrochloride
- Product Name
- trans-Cevimeline Hydrochloride
- CAS No.
- 107220-29-1
- Chemical Name
- trans-Cevimeline Hydrochloride
- Synonyms
- AF 102A HCl;trans-Cevimeline HCl;rac,trans-Cevimeline Hydrochloride;Cevimeline Impurity 7(trans-Cevimeline HCl);(2S)-2-methylspiro[1,3-oxathiolane-5,3'-1-azabicyclo[2.2.2]octane]:hydrochloride
- CBNumber
- CB13849872
- Molecular Formula
- C10H18ClNOS
- Formula Weight
- 235.77402
- MOL File
- 107220-29-1.mol
trans-Cevimeline Hydrochloride Property
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- Solid
- color
- White to Off-White
- Stability:
- Hygroscopic
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H332Harmful if inhaled
H351Suspected of causing cancer
H361Suspected of damaging fertility or the unborn child
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P281Use personal protective equipment as required.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P308+P313IF exposed or concerned: Get medical advice/attention.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P405Store locked up.
P501Dispose of contents/container to..…
trans-Cevimeline Hydrochloride Chemical Properties,Usage,Production
Description
trans-Cevimeline HCl, also known as AF 102A, is the trans-isomer of AF102B (Cevimeline). Cevimeline is a cholinergic analogue with glandular secretion stimulatory activity. Cevimeline binds to and activates muscarinic receptors, thereby increasing the secretions in exocrine salivary and sweat glands. This cholinergic agonist also increases the tone of smooth muscle in the gastrointestinal and urinary tracts. Cevimeline is being studied as a treatment for dry mouth caused by radiation therapy to the head and neck.
Uses
trans-Cevimeline Hydrochloride is a reagent in the preparation of spiro-oxathiolane/quinuclidine sulfoxide derivative for the treatment of central nervous and cholinergic system disease or disorders.
trans-Cevimeline Hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
trans-Cevimeline Hydrochloride Suppliers
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