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ROKITAMYCIN

Product Name
ROKITAMYCIN
CAS No.
74014-51-0
Chemical Name
ROKITAMYCIN
Synonyms
M-19-Q;TMS 19Q;Rokital;Rikamycin;Ricamycin;ROKITAMYCIN;T'urimyein H4;ROKITAMYCIN USP/EP/BP;3''-Propionylleucomycin A5;Leucomycin V, 4B-butanoate 3B-propanoate
CBNumber
CB1388574
Molecular Formula
C42H69NO15
Formula Weight
827.99
MOL File
74014-51-0.mol
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ROKITAMYCIN Property

Melting point:
116°
alpha 
D20 -71° (c = 1.0 in chloroform)
Boiling point:
879.3±65.0 °C(Predicted)
Density 
1.21±0.1 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
pka
13.06±0.70(Predicted)
CAS DataBase Reference
74014-51-0
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
API0004065
Product name
RICAMYCIN
Purity
95.00%
Packaging
100MG
Price
$885.31
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0004065
Product name
RICAMYCIN
Purity
95.00%
Packaging
1G
Price
$7192.5
Updated
2021/12/16
AHH
Product number
MT-58462
Product name
Rokitamycin
Purity
98%
Packaging
0.5g
Price
$910
Updated
2021/12/16
Crysdot
Product number
CD31000917
Product name
Ricamycin
Purity
95+%
Packaging
1g
Price
$1980
Updated
2021/12/16
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ROKITAMYCIN Chemical Properties,Usage,Production

Description

Rokitamycin is a semisynthetic macrolide antibiotic, closely related to miokamycin(2) both in structure and antimicrobial spectrum.

Originator

Toyo Jozo (Japan)

Definition

ChEBI: Rokitamycin is an organic molecular entity.

brand name

RICAMYCIN

Pharmaceutical Applications

3″-Propionyl leucomycin A5. A semisynthetic macrolide. Unstable in acid media.
The antibacterial spectrum is identical to that of erythromycin, but it is less active against Gram-positive cocci. It is poorly active against H. influenzae (MIC50 8 mg/L) and Mor. catarrhalis (MIC50 4 mg/L). It displays good activity against Campylobacter spp. (MIC50 0.1 mg/L), L. pneumophila (MIC50 0.1 mg/L) and M. pneumoniae (MIC50 0.003 mg/L). It is active against anaerobes, including some Bacteroides spp. (MIC50 <0.05 mg/L).
After a single oral dose of 600 mg, the peak plasma concentration was 1.9 mg/L after 0.6 h. Oral doses of 5, 10 and 15 mg/kg of a syrup formulation given to children achieved plasma concentrations of 0.26, 0.55 and 0.79 mg/L, respectively, after about 40 min. The half-life is around 2 h.
It is mainly eliminated in the bile; only about 2% appears in the urine. Its major metabolites are leucomycin A7, 10″-OH-rokitamycin (which show some antibacterial activity) and leucomycin V. In healthy adult volunteers, the proportions of rokitamycin and its metabolites in serum 30 min after a single oral dose of 1200 mg were 18% (leucomycin A7), 33% (10″-OH-rokitamycin) and 9% (leucomycin V). The pharmacokinetic behavior is not altered in patients with liver cirrhosis. It is available in Italy and Japan.

ROKITAMYCIN Preparation Products And Raw materials

Raw materials

Preparation Products

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ROKITAMYCIN Suppliers

Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12335
Advantage
58
Shanghai Han-Xiang Chemical Co., Ltd.
Tel
15971444841
Fax
18327183813
Email
amber@biochempartner.com
Country
China
ProdList
3061
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32165
Advantage
58
Shaanxi Dideu Medichem Co. Ltd
Tel
+86-029-89586680 +86-18192503167
Fax
+86-29-88380327
Email
1026@dideu.com
Country
China
ProdList
7724
Advantage
58
Shaanxi Dideu Medichem Co. Ltd
Tel
+86-29-87569262 +86-15319487004
Fax
029-88380327
Email
1015@dideu.com
Country
China
ProdList
2127
Advantage
58
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd
Tel
15229059051
Email
1027@dideu.com
Country
China
ProdList
9992
Advantage
58
Shanghai Yifei Biotechnology Co. , Ltd.
Tel
021-65675885 18964387627
Email
customer_service@efebio.com
Country
China
ProdList
11974
Advantage
58
Hangzhou FandaChem Co.,Ltd.
Tel
+8615858145714
Fax
+86-571-56059825
Email
FandaChem@Gmail.com
Country
China
ProdList
9214
Advantage
55
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View Lastest Price from ROKITAMYCIN manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
ROKITAMYCIN 74014-51-0
Price
US $1.00-1.00/KG
Min. Order
1g
Purity
99%
Supply Ability
50tons
Release date
2020-05-07

74014-51-0, ROKITAMYCINRelated Search:


  • 3''-Propionylleucomycin A5
  • Leucomycin V, 4B-butanoate 3B-propanoate (9CI)
  • Ricamycin
  • TMS 19Q
  • ROKITAMYCIN
  • Leummycin V 4B-bu-tanoate 3 B-propanoate
  • M-19-Q
  • Rikamycin
  • Rokital
  • T'urimyein H4
  • Leucomycin V, 4B-butanoate 3B-propanoate
  • ROKITAMYCIN USP/EP/BP
  • 74014-51-0