ERYTHROMYCIN LACTOBIONATE (200 MG)
- Product Name
- ERYTHROMYCIN LACTOBIONATE (200 MG)
- CAS No.
- 3847-29-8
- Chemical Name
- ERYTHROMYCIN LACTOBIONATE (200 MG)
- Synonyms
- Erythromycin lactobionate;Erythrocin lactobionate;ERYTHROMYCIN LACTOBIONATE USP(CRM STANDARD);Lactose azithroMycin;Erythomycin lactobionate;Azithromycin lactobionate;Moxifloxacin Impurity 146;Erythromycin lactobionate CRS;ERYTHROMYC LACTOBIONATE (200 MG);ERYTHROMYCIN LACTOBIONATE (200 MG)
- CBNumber
- CB5501658
- Molecular Formula
- C37H67NO13.C12H22O12
- Formula Weight
- 1092.22
- MOL File
- 3847-29-8.mol
ERYTHROMYCIN LACTOBIONATE (200 MG) Property
- Melting point:
- 145-150°
- Density
- 0.9083 (rough estimate)
- refractive index
- 1.5300 (estimate)
- storage temp.
- Refrigerator
- solubility
- Soluble in water, freely soluble in anhydrous ethanol and in methanol, very slightly soluble in acetone and in methylene chloride.
- form
- Solid
- color
- White to Off-White
- Water Solubility
- >20g/L(21 ºC)
Safety
- HS Code
- 2941500000
N-Bromosuccinimide Price
- Product number
- 17189
- Product name
- Erythromycin lactobionate
- Packaging
- 1g
- Price
- $57
- Updated
- 2024/03/01
- Product number
- 17189
- Product name
- Erythromycin lactobionate
- Packaging
- 5g
- Price
- $243
- Updated
- 2024/03/01
- Product number
- 17189
- Product name
- Erythromycin lactobionate
- Packaging
- 500mg
- Price
- $32
- Updated
- 2024/03/01
- Product number
- 17189
- Product name
- Erythromycin lactobionate
- Packaging
- 10g
- Price
- $426
- Updated
- 2024/03/01
- Product number
- E650040
- Product name
- ErythromycinLactobionate
- Packaging
- 500mg
- Price
- $215
- Updated
- 2021/12/16
ERYTHROMYCIN LACTOBIONATE (200 MG) Chemical Properties,Usage,Production
Description
Erythromycin is a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 50S ribosomal subunit, blocking the progression of nascent polypeptide chains. It is effective against a host of bacterial genera, including Streptococcus, Staphylococcus, and Haemophilus (MIC90s range from 0.015-2.0 mg/l). Erythromycin is known to potently inhibit the cytochrome P450 isoform CYP3A4, which can affect the metabolism of numerous clinically relevant medications. Erythromycin lactobionate is a soluble salt of erythromycin that is typically used for intraperitoneal or intravenous injections.
Chemical Properties
White or slightly yellow hygroscopic, powder.
Originator
Erythrocin,Abbott,US,1954
Uses
Erythromycin Lactobionate is an antibiotic used to reduce the prevalence of drug resistant bacteria as well as keeping constant the efficacy of other antibacterial drugs.
Uses
Macrolide antibacterial.
Manufacturing Process
A solution of erythromycin free base is prepared by dissolving 8.0 grams of erythromycin in 25 cc of acetone. 4.0 grams of lactobiono-delta-lactone is dissolved in 25 cc of water. The free lactobionic acid is formed in this solution and it has the molecular formula C12H22O12. The two solutions are mixed and evaporated to a gummy residue. This residue is dissolved in 60 cc of water and the solution is frozen and dried in vacuum by lyophilization. The dried residue of erythromycin lactobionate is a white amorphous powder and weighs 11.7 grams. The reaction product has an activity against B. subtilis of 420units per milligram. Its solubility in water is about 200 mg/cc and the melting point of the white powdery reaction product is 145° to 150°C.
brand name
Erythrocin (Abbott); Erythrocin (Hospira).
Therapeutic Function
Antibacterial
General Description
Erythromycin lactobionate is a water-soluble salt preparedby reacting erythromycin base with lactobiono-σ-lactone. Itoccurs as an amorphous powder that is freely soluble inwater and alcohol and slightly soluble in ether. It is intended,after reconstitution in sterile water, for intravenousadministration to achieve high plasma levels in the treatmentof serious infections.
ERYTHROMYCIN LACTOBIONATE (200 MG) Preparation Products And Raw materials
Raw materials
Preparation Products
ERYTHROMYCIN LACTOBIONATE (200 MG) Suppliers
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View Lastest Price from ERYTHROMYCIN LACTOBIONATE (200 MG) manufacturers
- Product
- ErythroMycin Lactobionate 3847-29-8
- Price
- US $1.00-1.00/KG
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 50tons
- Release date
- 2020-05-07
- Product
- Erythromycin lactobionate 3847-29-8
- Price
- US $0.00-0.00/Kg/Drum
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 1000kgs
- Release date
- 2021-11-16
- Product
- Erythromycin lactobionate 3847-29-8
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10