ChemicalBook > CAS DataBase List > ERYTHROMYCIN LACTOBIONATE (200 MG)

ERYTHROMYCIN LACTOBIONATE (200 MG)

Product Name
ERYTHROMYCIN LACTOBIONATE (200 MG)
CAS No.
3847-29-8
Chemical Name
ERYTHROMYCIN LACTOBIONATE (200 MG)
Synonyms
Erythromycin lactobionate;Erythrocin lactobionate;ERYTHROMYCIN LACTOBIONATE USP(CRM STANDARD);Lactose azithroMycin;Erythomycin lactobionate;Azithromycin lactobionate;Moxifloxacin Impurity 146;Erythromycin lactobionate CRS;ERYTHROMYC LACTOBIONATE (200 MG);ERYTHROMYCIN LACTOBIONATE (200 MG)
CBNumber
CB5501658
Molecular Formula
C37H67NO13.C12H22O12
Formula Weight
1092.22
MOL File
3847-29-8.mol
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ERYTHROMYCIN LACTOBIONATE (200 MG) Property

Melting point:
145-150°
Density 
0.9083 (rough estimate)
refractive index 
1.5300 (estimate)
storage temp. 
Refrigerator
solubility 
Soluble in water, freely soluble in anhydrous ethanol and in methanol, very slightly soluble in acetone and in methylene chloride.
form 
Solid
color 
White to Off-White
Water Solubility 
>20g/L(21 ºC)
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Safety

HS Code 
2941500000
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
17189
Product name
Erythromycin lactobionate
Packaging
1g
Price
$57
Updated
2024/03/01
Cayman Chemical
Product number
17189
Product name
Erythromycin lactobionate
Packaging
5g
Price
$243
Updated
2024/03/01
Cayman Chemical
Product number
17189
Product name
Erythromycin lactobionate
Packaging
500mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
17189
Product name
Erythromycin lactobionate
Packaging
10g
Price
$426
Updated
2024/03/01
TRC
Product number
E650040
Product name
ErythromycinLactobionate
Packaging
500mg
Price
$215
Updated
2021/12/16
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ERYTHROMYCIN LACTOBIONATE (200 MG) Chemical Properties,Usage,Production

Description

Erythromycin is a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 50S ribosomal subunit, blocking the progression of nascent polypeptide chains. It is effective against a host of bacterial genera, including Streptococcus, Staphylococcus, and Haemophilus (MIC90s range from 0.015-2.0 mg/l). Erythromycin is known to potently inhibit the cytochrome P450 isoform CYP3A4, which can affect the metabolism of numerous clinically relevant medications. Erythromycin lactobionate is a soluble salt of erythromycin that is typically used for intraperitoneal or intravenous injections.

Chemical Properties

White or slightly yellow hygroscopic, powder.

Originator

Erythrocin,Abbott,US,1954

Uses

Erythromycin Lactobionate is an antibiotic used to reduce the prevalence of drug resistant bacteria as well as keeping constant the efficacy of other antibacterial drugs.

Uses

Macrolide antibacterial.

Manufacturing Process

A solution of erythromycin free base is prepared by dissolving 8.0 grams of erythromycin in 25 cc of acetone. 4.0 grams of lactobiono-delta-lactone is dissolved in 25 cc of water. The free lactobionic acid is formed in this solution and it has the molecular formula C12H22O12. The two solutions are mixed and evaporated to a gummy residue. This residue is dissolved in 60 cc of water and the solution is frozen and dried in vacuum by lyophilization. The dried residue of erythromycin lactobionate is a white amorphous powder and weighs 11.7 grams. The reaction product has an activity against B. subtilis of 420units per milligram. Its solubility in water is about 200 mg/cc and the melting point of the white powdery reaction product is 145° to 150°C.

brand name

Erythrocin (Abbott); Erythrocin (Hospira).

Therapeutic Function

Antibacterial

General Description

Erythromycin lactobionate is a water-soluble salt preparedby reacting erythromycin base with lactobiono-σ-lactone. Itoccurs as an amorphous powder that is freely soluble inwater and alcohol and slightly soluble in ether. It is intended,after reconstitution in sterile water, for intravenousadministration to achieve high plasma levels in the treatmentof serious infections.

ERYTHROMYCIN LACTOBIONATE (200 MG) Preparation Products And Raw materials

Raw materials

Preparation Products

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ERYTHROMYCIN LACTOBIONATE (200 MG) Suppliers

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View Lastest Price from ERYTHROMYCIN LACTOBIONATE (200 MG) manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
ErythroMycin Lactobionate 3847-29-8
Price
US $1.00-1.00/KG
Min. Order
1g
Purity
99%
Supply Ability
50tons
Release date
2020-05-07
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Erythromycin lactobionate 3847-29-8
Price
US $0.00-0.00/Kg/Drum
Min. Order
1KG
Purity
98%min
Supply Ability
1000kgs
Release date
2021-11-16
Zhuozhou Wenxi import and Export Co., Ltd
Product
Erythromycin lactobionate 3847-29-8
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10

3847-29-8, ERYTHROMYCIN LACTOBIONATE (200 MG)Related Search:

Sodium lactobionate Sodium dichloroisocyanurate Cefuroxime PotassiuM sodiuM Dehydroandrographolide Succinate Lactobionic acid Azithromycin D-(+)-ALLOSE ERYTHROMYCIN A DIHYDRATE ERYTHROMYCIN LACTOBIONATE (200 MG) BETA-D-ALLOSE Gluconic acid N-DEMETHYL ERYTHROMYCIN A Erythromycin Ammonium-D-xylonate METHYL-BETA-D-RIBOPYRANOSE

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  • (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-Dimethylamino-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecane-2,10-dione (2R,
  • Erythromycin lactobionate
  • Lactose azithroMycin
  • ERYTHROMYCIN LACTOBIONATE (200 MG)
  • 4-o-beta-d-galactopyranosyl-d-gluconicacicompd.witherythromycin(1:1)
  • 4-o-beta-d-galactopyranosyl-d-gluconicacidcompd.witherythromycin
  • erythromycinmono(4-o-beta-d-galactopyranosyl-d-gluconate)(salt)
  • lactobionicacid,compd.witherythromycin(1:1)
  • Erythromycin lactobionate CRS
  • ERYTHROMYC LACTOBIONATE (200 MG)
  • ERYTHROMYCIN LACTOBIONATE (200 MG) USP/EP/BP
  • ERYTHROMYCIN LACTOBIONATE USP/EP/BP
  • Erythromycin Lactobionate (1247003)
  • Moxifloxacin Impurity 146
  • 3847-29-8
  • C49H87NO24
  • CC48H89NO25
  • C2C47H89NO25
  • C49H89NO25
  • API
  • Peptide Synthesis/Antibiotics