HUMAN IL-17
Description Source Background- Product Name
- HUMAN IL-17
- Chemical Name
- HUMAN IL-17
- Synonyms
- IL-17;CTLA-8;IL-17A;HUMAN IL-17;IL-17, HUMAN;HUMAN CTLA-8;IL-17A from rat;interleukin 17A;HUMAN IL-17A/17A;HUMAN INTERLEUKIN 17
- CBNumber
- CB1390041
- Formula Weight
- 0
- MOL File
- Mol file
HUMAN IL-17 Property
- storage temp.
- −20°C
- form
- lyophilized powder
- color
- off-white to yellow
- biological source
- human
Safety
- WGK Germany
- 3
- Storage Class
- 11 - Combustible Solids
N-Bromosuccinimide Price
- Product number
- SRP0675
- Product name
- IL-17A
- Purity
- recombinant, expressed in E. coli
- Packaging
- 5μg
- Price
- $132
- Updated
- 2025/07/31
- Product number
- SRP3080
- Product name
- IL-17 human
- Purity
- Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture
- Packaging
- 25μg
- Price
- $293
- Updated
- 2025/07/31
- Product number
- SRP0675
- Product name
- IL-17A
- Purity
- recombinant, expressed in E. coli
- Packaging
- 25μg
- Price
- $322
- Updated
- 2025/07/31
- Product number
- I3525
- Product name
- Interleukin-17A human
- Purity
- ≥98% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
- Packaging
- 50μg
- Price
- $748
- Updated
- 2025/07/31
- Product number
- H7791
- Product name
- Interleukin-17A human
- Purity
- IL-17A, recombinant, expressed in HEK 293 cells, HumanKine?, suitable for cell culture
- Packaging
- 10μg
- Price
- $219
- Updated
- 2025/07/31
HUMAN IL-17 Chemical Properties,Usage,Production
Uses
The gene IL17A (interleukin 17A), also referred to as IL-17, is mapped to human chromosome 6p12.2. The gene contain three exons and encodes a proinflammatory cytokine produced by activated T cells.
Biological Activity
The cytokine interleukin 17A is involved in the activation of proinflammatory cytokines, chemokines, and cell adhesion molecules in several cell types such as, macrophages, dendritic cells, T cells, synovial cells, and endothelial cells. Overexpression of this protein has been associated with rheumatoid arthritis, systemic lupus erythematosus, Behcet′s disease, allograft rejection, nephritic syndrome, asthma, and multiple sclerosis. In mice, it has been observed to be implicated in the development of allergic and autoimmune diseases. Polymorphism in IL17A gene has been associated with lung cancer.
Description
Interleukin-17A Human Recombinant produced in E.Coli is a homodimeric, non-glycosylated polypeptide chain containing a total of 264 amino acids (2 chains of 132 aa) and having a molecular mass of 31kDa.
The IL-17 is purified by proprietary chromatographic techniques.
Source
Escherichia Coli
Background
IL17 is a proinflammatory cytokine produced by activated T cells. IL-17 regulates the activities of NF-kappaB and mitogen-activated protein kinases. Interleukin-17 can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
HUMAN IL-17 Preparation Products And Raw materials
Raw materials
Preparation Products
HUMAN IL-17 Suppliers
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- 821-50328103-801 18930552037
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- China
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