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Cadralazine

Product Name
Cadralazine
CAS No.
64241-34-5
Chemical Name
Cadralazine
Synonyms
DC-26;DC 826;Cadral;ISF-469;Cadrilan;Cadraten;Presmode;ISF 2469;CGP 18684E;Cadralazine
CBNumber
CB1398719
Molecular Formula
C12H21N5O3
Formula Weight
283.33
MOL File
64241-34-5.mol
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Cadralazine Property

Melting point:
160-162°
Boiling point:
425.88°C (rough estimate)
Density 
1.1585 (rough estimate)
refractive index 
1.6500 (estimate)
storage temp. 
2-8°C
solubility 
DMSO : 250 mg/mL (882.36 mM; ultrasonic and warming and heat to 60°C)
pka
6.0(at 25℃)
CAS DataBase Reference
64241-34-5
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Safety

Toxicity
LD50 in rats, dogs (mg/kg): 269, approx 400 i.v.; 2060, >2000 orally (Semeraro); in mice (mg/kg): 700 i.p. (Parravicini)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
API0001804
Product name
CADRALAZINE
Purity
95.00%
Packaging
1MG
Price
$152.25
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0001804
Product name
CADRALAZINE
Purity
95.00%
Packaging
100MG
Price
$885.31
Updated
2021/12/16
Chemenu
Product number
CM164580
Product name
ethyl2-(6-(ethyl(2-hydroxypropyl)amino)pyridazin-3-yl)hydrazine-1-carboxylate
Purity
95%
Packaging
1g
Price
$1118
Updated
2021/12/16
Crysdot
Product number
CD31001189
Product name
Cadralazine
Purity
95+%
Packaging
1g
Price
$1186
Updated
2021/12/16
Arctom
Product number
AS499696
Product name
Cadralazine
Purity
≥95%
Packaging
1g
Price
$1863
Updated
2021/12/16
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Cadralazine Chemical Properties,Usage,Production

Description

Cadralazine is a vasodilatory antihypertensive reportedly better-tolerated and longer-acting than hydralazine. It is useful as a second-line treatment in the management of hypertension.

Originator

ISF;(Smith Mine) (Italy)

Definition

ChEBI: Cadralazine is an organic molecular entity.

brand name

Cadraten 21 cpr 20 mg;Cadraten 30 cpr 10 mg;Cadraten 30 cpr 15 mg;Cadratin;Cadrilan.

World Health Organization (WHO)

Cadralazine, a peripheral vasodilator, was introduced in 1989 for the treatment of arterial hypertension.In 1992, its association with serious side effects led to the refusal of registration in Norway. Animal experiments have demonstrated drug-related impairment of thyroid function as well as potential carcinogenicity and genotoxicity. It remains available for treatment of hypertension in Italy.

Cadralazine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Cadralazine manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
Cadralazine 64241-34-5
Price
US $0.00-0.00/Kg
Min. Order
1KG
Purity
99.0%
Supply Ability
500 MT
Release date
2020-05-09

64241-34-5, CadralazineRelated Search:


  • HYDRAZINECARBOXYLIC ACID, 2-[6-[ETHYL(2-HYDROXYPROPYL)AMINO]-3-PYRIDAZINYL]-, ETHYL ESTER
  • Cadralazine
  • Cadral
  • Cadraten
  • Cadrilan
  • CGP 18684E
  • DC 826
  • ISF 2469
  • Presmode
  • (2-hydroxypropyl)amino]-3-pyridazinyl]hydrazinecarboxylic acid ethyl ester
  • 2-[6-[Ethyl
  • 2-[6-[Ethyl(2-hydroxypropyl)amino]pyridazin-3-yl]hydrazine-1-carboxylic acid ethyl ester
  • 3-[6-[N-Ethyl-N-(2-hydroxypropyl)amino]pyridazin-3-yl]carbazic acid ethyl ester
  • Cardralazine
  • Ethyl 2-(6-(ethyl(2-hydroxypropyl)aMino)pyridazin-3-yl)hydrazinecarboxylate
  • DC-26
  • ISF-469
  • Cadralazine USP/EP/BP
  • Ethyl 2-(6-(ethyl(2-hydroxypropyl)amino)pyridazin-3-yl)hydrazine-1-carboxylate
  • 64241-34-5
  • C12H21N5O3