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(5-TRIFLUOROMETHYL-PYRIDIN-2-YL) METHANOL

Product Name
(5-TRIFLUOROMETHYL-PYRIDIN-2-YL) METHANOL
CAS No.
31181-84-7
Chemical Name
(5-TRIFLUOROMETHYL-PYRIDIN-2-YL) METHANOL
Synonyms
5-(trifluoromethyl)-2-Pyridinemethanol;2-Pyridinemethanol, 5-(trifluoromethyl)-;[5-(Trifluoromethyl)-2-pyridinyl]methanol;(5-TRIFLUOROMETHYL-PYRIDIN-2-YL) METHANOL;2-HydroxyMethyl-5-(TrifluorMethyl)-Pyridine;2-(Hydroxymethyl)-5-(trifluoromethyl)pyridine;(5-TRIFLUOROMETHYL-PYRIDIN-2-YL) METHANOL ISO 9001：2015 REACH
CBNumber
CB1401570
Molecular Formula
C7H6F3NO
Formula Weight
177.12
MOL File
31181-84-7.mol
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(5-TRIFLUOROMETHYL-PYRIDIN-2-YL) METHANOL Property

Boiling point:
215.5±35.0 °C(Predicted)
Density 
1.362±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
13.16±0.10(Predicted)
Appearance
Light yellow to yellow Liquid
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Safety

HazardClass 
IRRITANT
HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
T899093
Product name
(5-(trifluoromethyl)pyridin-2-yl)methanol
Packaging
50mg
Price
$45
Updated
2021/12/16
AK Scientific
Product number
3322AB
Product name
(5-(Trifluoromethyl)pyridin-2-yl)methanol
Packaging
100mg
Price
$103
Updated
2021/12/16
Matrix Scientific
Product number
055505
Product name
[5-(Trifluoromethyl)-2-pyridinyl]methanol
Purity
95+%
Packaging
500mg
Price
$175
Updated
2021/12/16
Matrix Scientific
Product number
055505
Product name
[5-(Trifluoromethyl)-2-pyridinyl]methanol
Purity
95+%
Packaging
1g
Price
$195
Updated
2021/12/16
Apolloscientific
Product number
PC200105
Product name
2-(Hydroxymethyl)-5-(trifluoromethyl)pyridine
Packaging
500mg
Price
$276
Updated
2021/12/16
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(5-TRIFLUOROMETHYL-PYRIDIN-2-YL) METHANOL Chemical Properties,Usage,Production

Synthesis

124236-37-9

31181-84-7

IV. General procedure for the synthesis of 5-trifluoromethylpyridine-2-methanol: To a solution of methyl 5-trifluoromethylpyridine-2-carboxylate (2 g, 9.75 mmol) in methanol (30 mL) was added sodium borohydride (738 mg, 19.5 mmol) in one batch at 0 °C. The reaction mixture was stirred at room temperature for 2 hours and then concentrated. The residue was diluted with water (30 mL), acidified with 1N hydrochloric acid to pH ~5, and extracted with ethyl acetate (3 x 50 mL). The organic phases were combined, dried over anhydrous sodium sulfate and concentrated, and finally purified by silica gel column chromatography to afford 5-trifluoromethylpyridine-2-methanol as a colorless oil (1.6 g, 93% yield).1H NMR (400 MHz, CDCl3) δppm: 8.82 (s, 1H), 7.90-7.92 (m, 1H), 7.40-7.42 (m, 1H ), 4.82-4.83 (m, 2H), 3.44-3.46 (m, 1H); ES-LCMS m/z 178 ([M+H]+).

References

[1] Patent: WO2013/166621, 2013, A1. Location in patent: Page/Page column 48
[2] Patent: CN106831840, 2017, A. Location in patent: Paragraph 0102; 0103; 0104
[3] Patent: US2009/124666, 2009, A1. Location in patent: Page/Page column 25-26

(5-TRIFLUOROMETHYL-PYRIDIN-2-YL) METHANOL Preparation Products And Raw materials

Raw materials

Preparation Products

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(5-TRIFLUOROMETHYL-PYRIDIN-2-YL) METHANOL Suppliers

China 105 India 1 United Kingdom 1 United States 13 Global 120
A.J Chemicals
Tel
--
Fax
--
Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58
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View Lastest Price from (5-TRIFLUOROMETHYL-PYRIDIN-2-YL) METHANOL manufacturers

PNP Biotech Co. Ltd
Product
(5-(trifluoromethyl)pyridin-2-yl)methanol 31181-84-7
Price
US $0.00/kg
Min. Order
25kg
Purity
98%
Supply Ability
Inquiry
Release date
2023-07-13
Dideu Industries Group Limited
Product
(5-TRIFLUOROMETHYL-PYRIDIN-2-YL) METHANOL 31181-84-7
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons min
Release date
2021-08-30
Career Henan Chemical Co
Product
(5-TRIFLUOROMETHYL-PYRIDIN-2-YL) METHANOL 31181-84-7
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
Customized
Release date
2019-12-17

31181-84-7, (5-TRIFLUOROMETHYL-PYRIDIN-2-YL) METHANOLRelated Search:

3-CHLORO-5-(TRIFLUOROMETHYL)PYRIDINE-2-CARBOXYLIC ACID 5-(Trifluoromethyl)pyridine-2-carboxylic acid 1-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-1-ETHANOL (5-TRIFLUOROMETHYL-PYRIDIN-2-YL) METHANOL 2-Pyridinecarboxylic acid,3-chloro-5-(trifluoromethyl)-,methyl ester [3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL](2,4-DICHLOROPHENYL)METHYL N-[3-(TRIFLUOROMETHYL)PHENYL]CARBAMATE N-([3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]METHOXY)-N-[(DIMETHYLAMINO)METHYLENE]UREA N-([3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]METHOXY)-N-(([(2,4-DICHLOROBENZYL)OXY]IMINO)METHYL)UREA [3-(2,4-DICHLOROPHENOXY)-5-(TRIFLUOROMETHYL)-2-PYRIDINYL](2,4-DICHLOROPHENYL)METHANOL 3-CHLORO-5-(TRIFLUOROMETHYL)-2-([3-(TRIFLUOROMETHYL)PHENOXY]METHYL)PYRIDINE N-([3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]METHOXY)UREA 1-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]ETHYL 2,4-DICHLOROPHENYL ETHER [3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL](4-METHOXYPHENYL)METHANOL 2-(4-[[3-CHLORO-5-(TRIFLUOROMETHYL)PYRIDIN-2-YL]METHOXY]PHENYL)-N'-HYDROXYETHANIMIDAMIDE (2,4-DICHLOROPHENYL)[3-PHENOXY-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]METHANOL [3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL](2,4-DICHLOROPHENYL)METHANOL N-([3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]METHOXY)-N-[(METHOXYIMINO)METHYL]UREA N3-(4-([3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDYL]METHOXY)PHENYL)-6-CHLORONICOTINAMIDE

  • (5-TRIFLUOROMETHYL-PYRIDIN-2-YL) METHANOL
  • 2-(Hydroxymethyl)-5-(trifluoromethyl)pyridine
  • 5-(trifluoromethyl)-2-Pyridinemethanol
  • [5-(Trifluoromethyl)-2-pyridinyl]methanol
  • 2-HydroxyMethyl-5-(TrifluorMethyl)-Pyridine
  • 2-Pyridinemethanol, 5-(trifluoromethyl)-
  • (5-TRIFLUOROMETHYL-PYRIDIN-2-YL) METHANOL ISO 9001：2015 REACH
  • 31181-84-7