5-(Trifluoromethyl)pyridine-2-carboxylic acid

Product Name: 5-(Trifluoromethyl)pyridine-2-carboxylic acid
CAS No.: 80194-69-0
Chemical Name: 5-(Trifluoromethyl)pyridine-2-carboxylic acid
Synonyms: 5-Trifluoromethyl-2-Pyridineca;5-(TRIFLUOROMETHYL)PICOLINIC ACID;5-trifluoro-2-pyridinecarboxylic acid;5-TRIFLUOROMETHYL-2-PYRIDINECARBOXYLIC ACID;2-Carboxylic acid-5-trifluoromethylpyridine;5-(Trifluoromethyl)pyridine-2-carboxylicaci;5-(TRIFLUOROMETHYL)PYRIDINE-2-CARBOXYLIC ACID;5- three-2-forMic acidfluorineMethyl pyridine;5-(Trifluoromethy1)pyridine-2-carboxylic acid;5-((trifluoromethyl))-pyridin-2-carboxylic acid
CBNumber: CB4476461
Molecular Formula: C7H4F3NO2
Formula Weight: 191.11
MOL File: 80194-69-0.mol

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5-(Trifluoromethyl)pyridine-2-carboxylic acid Property

Melting point:: 135-137°C
Boiling point:: 273.7±40.0 °C(Predicted)
Density: 1.484±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: DMSO (Slightly), Methanol (Slightly)
pka: 3.13±0.10(Predicted)
form: Powder
color: Pale brown
Water Solubility: Slightly soluble in water.
InChI: InChI=1S/C7H4F3NO2/c8-7(9,10)4-1-2-5(6(12)13)11-3-4/h1-3H,(H,12,13)
InChIKey: NJHGVAYLDHROPT-UHFFFAOYSA-N
SMILES: C1(C(O)=O)=NC=C(C(F)(F)F)C=C1
CAS DataBase Reference: 80194-69-0(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 2933399990
Storage Class: 11 - Combustible Solids
Hazard Classifications: Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 700630
Product name: 5-(Trifluoromethyl)pyridine-2-carboxylic acid
Purity: 95%
Packaging: 500mg
Price: $64.5
Updated: 2025/07/31

TCI Chemical

Product number: T2975
Product name: 5-(Trifluoromethyl)-2-pyridinecarboxylic Acid
Purity: >98.0%(GC)(T)
Packaging: 1g
Price: $34
Updated: 2025/07/31

TCI Chemical

Product number: T2975
Product name: 5-(Trifluoromethyl)-2-pyridinecarboxylic Acid
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $125
Updated: 2025/07/31

TRC

Product number: T791430
Product name: 5-(Trifluoromethyl)picolinicAcid
Packaging: 50g
Price: $245
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 38055
Product name: 5-(Trifluoromethyl)picolinicacid
Purity: 95+%
Packaging: 1g
Price: $324
Updated: 2021/12/16

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5-(Trifluoromethyl)pyridine-2-carboxylic acid Chemical Properties,Usage,Production

Uses

5-(Trifluoromethyl)pyridine-2-carboxylic acid is an intermediate used in the synthesis of β-secretase (BACE) inhibitors.

Uses

5-(Trifluoromethyl)pyridine-2-carboxylic acid is an intermediate used in the synthesis of β-secretase (BACE) inhibitors.

5-(Trifluoromethyl)pyridine-2-carboxylic acid Preparation Products And Raw materials

Raw materials

(Trifluoromethyl)trimethylsilane Hexane Nitrogen N-Methyl-2-pyrrolidone N,N-Dimethylformamide Toluene Carbon dioxide Tetrahydrofuran Diethyl ether Iodine Ethyl acetate 2,5-Dibromopyridine n-Butyllithium

Preparation Products

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5-(Trifluoromethyl)pyridine-2-carboxylic acid Suppliers

Canada 1 China 179 Germany 2 India 4 Italy 1 Japan 1 Switzerland 1 Ukraine 1 United Kingdom 6 United States 22 Global 218

Fuxin Custchem Fine Chemical Co., Ltd.

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View Lastest Price from 5-(Trifluoromethyl)pyridine-2-carboxylic acid manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: 5-(Trifluoromethyl)pyridine-2-carboxylic acid 80194-69-0
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000KGS
Release date: 2025-03-01

Henan Fengda Chemical Co., Ltd

Product: 5-(Trifluoromethyl)pyridine-2-carboxylic acid 80194-69-0
Price: US $5.00-0.10/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-04-08

Dideu Industries Group Limited

Product: 5-(Trifluoromethyl)pyridine-2-carboxylic acid 80194-69-0
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons min
Release date: 2021-08-25

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5-(Trifluoromethyl)pyridine-2-carboxylicaci

80194-69-0

Carboxylic Acids

Pyridines

Carboxylic Acids

Fluorine series