ChemicalBook > CAS DataBase List > (LEU31,PRO34)-NEUROPEPTIDE Y (HUMAN, RAT)

(LEU31,PRO34)-NEUROPEPTIDE Y (HUMAN, RAT)

Product Name
(LEU31,PRO34)-NEUROPEPTIDE Y (HUMAN, RAT)
CAS No.
132699-73-1
Chemical Name
(LEU31,PRO34)-NEUROPEPTIDE Y (HUMAN, RAT)
Synonyms
[LEU31,PRO34] NPY, HUMAN;[Leu31,Pro34]-Neuropeptide Y;M.W. 4240.67 C189H284N54O56S;(LEU31,PRO34)-NPY (HUMAN, RAT);[LEU31,PRO34] NEUROPEPTIDE Y, HUMAN;YPSKPDNPGEDAPAEDMARYYSALRHYINLLTRPRY-NH2;[Leu31,Pro3]-Neuropeptide Y (human, rat);(LEU31,PRO34)-NEUROPEPTIDE Y (HUMAN, RAT);[Leu31, Pro34]-Neuropeptide Y, human, rat - 1 mg;(Leu??,Pro??)-Neuropeptide Y (human, rat) trifluoroacetate salt
CBNumber
CB1413522
Molecular Formula
C189H284N54O56S
Formula Weight
4240.67046
MOL File
132699-73-1.mol
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(LEU31,PRO34)-NEUROPEPTIDE Y (HUMAN, RAT) Property

storage temp. 
−20°C
solubility 
Soluble in DMSO
form 
Powder
Water Solubility 
Soluble to 1 mg/ml in water
Sequence
Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pro-Ala-Glu-Asp-Met-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Leu-Thr-Arg-Pro-Arg-Tyr-NH2
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris
Product number
1176
Product name
[Leu31,Pro34]-NeuropeptideY(human,rat)
Packaging
200U
Price
$162
Updated
2021/12/16
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(LEU31,PRO34)-NEUROPEPTIDE Y (HUMAN, RAT) Chemical Properties,Usage,Production

Uses

[Leu31,Pro34]-Neuropeptide Y(human,rat) is a specific neuropeptide Y Y1 receptor agonist. [Leu31,Pro34]-Neuropeptide Y(human,rat) slao activates Y4, Y5. [Leu31,Pro34]-Neuropeptide Y(human,rat) can increase blood pressure in anesthetized rats and increases food intake[1][2].

in vivo

[Leu31,Pro34]-Neuropeptide Y(human,rat) (30 pmol; microinjected into paraventricular nucleus) increases food intake in the rats (350±400 g)[3].

IC 50

NPY Y1 receptor; NPY Y4 receptor; NPY Y5 receptor

storage

Store at -20°C

References

[1] J Fuhlendorff, et al. [Leu31, Pro34]neuropeptide Y: a specific Y1 receptor agonist. Proc Natl Acad Sci U S A. 1990 Jan;87(1):182-6. DOI:10.1073/pnas.87.1.182
[2] K McCrea, et al. 2-36[K4,RYYSA(19-23)]PP a novel Y5-receptor preferring ligand with strong stimulatory effect on food intake. Regul Pept. 2000 Feb 8;87(1-3):47-58. DOI:10.1016/s0167-0115(99)00108-1
[3] A Kask, et al. Evidence for involvement of neuropeptide Y receptors in the regulation of food intake: studies with Y1-selective antagonist BIBP3226. Br J Pharmacol. 1998 Aug;124(7):1507-15. DOI:10.1038/sj.bjp.0701969

(LEU31,PRO34)-NEUROPEPTIDE Y (HUMAN, RAT) Preparation Products And Raw materials

Raw materials

Preparation Products

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132699-73-1, (LEU31,PRO34)-NEUROPEPTIDE Y (HUMAN, RAT)Related Search:


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