BOC-3-AMINO-4-METHYLBENZOIC ACID
- Product Name
- BOC-3-AMINO-4-METHYLBENZOIC ACID
- CAS No.
- 231958-04-6
- Chemical Name
- BOC-3-AMINO-4-METHYLBENZOIC ACID
- Synonyms
- BOC-(3)ATL(4)-OH;BOC-(3)ABZ(4-ME)-OH;BOC-3-AMINO-4-METHYLBENZOIC ACID;3-(Boc-amino)-4-methylbenzoic acid;N-T-BUTOXYCARBONYL-3-AMINO-4-TOLUIC ACID;3--4-Methylbenzoicacid 231958-04-6;N-T-BUTOXYCARBONYL-3-AMINO-4-METHYL-BENZOIC ACID;3-[(t-Butoxycarbonyl)amino]-4-methylbenzoic acid;3-[(tert-butyloxycarbonyl)aMino]-4-Methylbenzoic acid;3-[[(1,1-Dimethylethoxy)carbonyl]amino]-4-methylbenzoic acid
- CBNumber
- CB1421172
- Molecular Formula
- C13H17NO4
- Formula Weight
- 251.28
- MOL File
- Mol file
BOC-3-AMINO-4-METHYLBENZOIC ACID Property
- Boiling point:
- 354.3±35.0 °C(Predicted)
- Density
- 1.212±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 4.32±0.10(Predicted)
- Appearance
- White to off-white Solid
Safety
- HazardClass
- IRRITANT
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P272Contaminated work clothing should not be allowed out of the workplace.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P363Wash contaminated clothing before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- CS-W021750
- Product name
- 3-((tert-Butoxycarbonyl)amino)-4-methylbenzoicacid
- Purity
- >98.0%
- Packaging
- 1g
- Price
- $82
- Updated
- 2021/12/16
- Product number
- 1519AB
- Product name
- 3-((tert-Butoxycarbonyl)amino)-4-methylbenzoicacid
- Packaging
- 100mg
- Price
- $95
- Updated
- 2021/12/16
- Product number
- 041687
- Product name
- Boc-3-amino-4-methylbenzoic acid
- Purity
- 95%
- Packaging
- 1g
- Price
- $126
- Updated
- 2021/12/16
- Product number
- AAA0004016
- Product name
- BOC-3-AMINO-4-METHYLBENZOIC ACID
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $188.1
- Updated
- 2021/12/16
- Product number
- CS-W021750
- Product name
- 3-((tert-Butoxycarbonyl)amino)-4-methylbenzoicacid
- Purity
- >98.0%
- Packaging
- 5g
- Price
- $286
- Updated
- 2021/12/16
BOC-3-AMINO-4-METHYLBENZOIC ACID Chemical Properties,Usage,Production
Synthesis
24424-99-5
2458-12-0
231958-04-6
To a mixed solution of 3-amino-4-methylbenzoic acid (2.0 g, 13.2 mmol) in water (25 mL) and 1 N sodium hydroxide (25 mL) was added di-tert-butyl dicarbonate (4.3 g, 19.8 mmol). The reaction mixture was stirred at room temperature for 18 hours. After completion of the reaction, the mixture was extracted by partitioning with ethyl acetate and 5% aqueous citric acid. The organic layer was separated, washed sequentially with water and saturated saline, and then dried with anhydrous magnesium sulfate. The desiccant was removed by filtration and the filtrate was concentrated under reduced pressure to give 3-((tert-butoxycarbonyl)amino)-4-methylbenzoic acid as a pink solid (3.3 g, quantitative yield).
References
[1] Patent: US2012/142708, 2012, A1. Location in patent: Page/Page column 23
[2] Patent: WO2005/42537, 2005, A1. Location in patent: Page/Page column 46; 47
[3] Bioorganic and Medicinal Chemistry Letters, 2014, vol. 24, # 16, p. 3700 - 3705
[4] European Journal of Organic Chemistry, 2001, # 2, p. 311 - 322
[5] Journal of Medicinal Chemistry, 2008, vol. 51, # 1, p. 4 - 16
BOC-3-AMINO-4-METHYLBENZOIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from BOC-3-AMINO-4-METHYLBENZOIC ACID manufacturers
- Product
- BOC-3-AMINO-4-METHYLBENZOIC ACID 231958-04-6
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 200kg
- Release date
- 2018-12-24