ChemicalBook > CAS DataBase List > C16 CERAMIDE

C16 CERAMIDE

Product Name
C16 CERAMIDE
CAS No.
24696-26-2
Chemical Name
C16 CERAMIDE
Synonyms
N-PALMITOYL-D-SPHINGOSINE;N-Palmitoylsphingosine;N-PALMITOYL-D-ERYTHRO-SPHINGOSINE;N-HEXADECANOYL-D-ERYTHRO-SPHINGOSINE;C16 CERAMIDE;CERAMIDE-C16;16:0 CERAMIDE;PALMITOYL CERAMIDE;N-PALMITOYL CERAMIDE;C16-D-ERYTHRO-CERAMIDE
CBNumber
CB1421758
Molecular Formula
C34H67NO3
Formula Weight
537.9
MOL File
24696-26-2.mol
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C16 CERAMIDE Property

Melting point:
94-95 °C
Boiling point:
614.41°C (rough estimate)
Density 
0.9596 (rough estimate)
refractive index 
1.6630 (estimate)
storage temp. 
−20°C
solubility 
Soluble in DMF at 0.15mg/ml
pka
13.54±0.20(Predicted)
form 
Crystalline Powder
color 
White
InChIKey
YDNKGFDKKRUKPY-TURZORIXSA-N
SMILES
C(N[C@@H](CO)[C@H](O)/C=C/CCCCCCCCCCCCC)(=O)CCCCCCCCCCCCCCC
CAS DataBase Reference
24696-26-2
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Safety

Hazard Codes 
Xi
Safety Statements 
24/25
WGK Germany 
3
HS Code 
29225000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
43799
Product name
N-Palmitoyl-D-sphingosine
Purity
≥98.0% (TLC)
Packaging
50mg
Price
$238
Updated
2025/07/31
Sigma-Aldrich
Product number
43799
Product name
N-Palmitoyl-D-sphingosine
Purity
≥98.0% (TLC)
Packaging
250mg
Price
$434
Updated
2025/07/31
Cayman Chemical
Product number
10681
Product name
C-16 Ceramide
Purity
≥98%
Packaging
1mg
Price
$20
Updated
2024/03/01
Cayman Chemical
Product number
10681
Product name
C-16 Ceramide
Purity
≥98%
Packaging
5mg
Price
$78
Updated
2024/03/01
Cayman Chemical
Product number
10681
Product name
C-16 Ceramide
Purity
≥98%
Packaging
10mg
Price
$127
Updated
2024/03/01
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C16 CERAMIDE Chemical Properties,Usage,Production

Chemical Properties

White Crystalline Solid

Uses

A predominant, rather hydrophobic natural ceramide. Activates a cytosolic serine/threonine protein phosphatase in T9 cells; induces EGF receptor phosphorylation in A-431 cells; stimulates ceramide-activated protein kinase

Uses

An endogenous ceramide that acts as a lipid second messenger to regulate apoptosis and stress signaling.

Definition

ChEBI: N-hexadecanoylsphingosine is a N-acylsphingosine in which the ceramide N-acyl group is specified as hexadecanoyl (palmitoyl). It has a role as a Mycoplasma genitalium metabolite and a human blood serum metabolite. It is a N-acylsphingosine, a Cer(d34:1) and a N-palmitoyl-sphingoid base. It is functionally related to a hexadecanoic acid.

Biological Activity

C16 Ceramide levels are elevated in chronic alcohol-related liver disease (ALD). In general, ceramide inhibits mitochondrial function and insulin signaling. They are essential component of cell membrane and are involved in lipid raft formation. C16 ceramide based analog (C2-C16 CCPS) is potential anticancer agent used in chemotherapy. The levels of C16 ceramide and its ratio with other ceramides is regarded as a biomarker in predicting coronary artery disease (CAD). It interacts with the DNA-binding domain of tumor suppressor protein p53 and activates p53.

C16 CERAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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C16 CERAMIDE Suppliers

Shanghai Renshi Pharmatech Co., LTD
Tel
021-61150625 17721318029
Fax
021-26018649
Email
info@renshipharma.com
Country
China
ProdList
161
Advantage
55
Shanghai Jindi Pharmaceutical Technology Co., Ltd
Tel
13564401937
Email
wangtao@jindipharma.com.cn
Country
China
ProdList
22
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15838
Advantage
69
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18729
Advantage
57
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17770
Advantage
75
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 13167063860
Fax
021-50323701
Email
anhua.mao@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
Yichang Zhongyitai Trading Co., Ltd.
Tel
0717-6449896 13886658719
Fax
0717-6558598
Email
root@zhongyitai.com
Country
China
ProdList
1978
Advantage
58

24696-26-2, C16 CERAMIDERelated Search:


  • D-ERYTHRO-SPHINGOSINE, N-PALMITOYL
  • CERAMIDE-C16
  • C16 CERAMIDE
  • C16-D-ERYTHRO-CERAMIDE
  • C16 ceramide, N-Hexadecanoyl-D-sphingosine, N-Palmitoyl-D-erythro-sphingosine, Palmitoyl ceramide
  • N-Palmitoyl-D-sphingosine semisynthetic from bovine brain D-sphingosine
  • N-PALMITOYL-D-ERYTHRO-SPHINGOSINE, SYNTHETICAL, 98% (99+% E.E.)
  • N-Palmitoyl-D-erythro-sphingosineCeramide C16
  • N-Palmitoyl-D-erythro-sphingosine, N-Hexadecanoyl-D-erythro-sphingosine, Palmitoyl ceramide
  • N-PalMitoyl-D-erythro-sphingosine, synthetical, (99+% E.E.)
  • (2S,3R,4E)-2-N-PalMitoyloctadecasphinga-4-ene
  • N-[(1S,2R,3E)-2-Hydroxy-1-(hydroxyMethyl)-3-heptadecen-1-yl]-hexadecanaMide
  • 16:0 CERAMIDE
  • PALMITOYL CERAMIDE
  • N-PALMITOYL CERAMIDE
  • N-PALMITOYL-D-ERYTHRO-SPHINGOSINE
  • N-PALMITOYL-D-SPHINGOSINE
  • N-PALMITOYLSPHINGOSINE, D-ERYTHRO
  • N-HEXADECANOYL-D-ERYTHRO-SPHINGOSINE
  • N-HEXADECANOYL-D-SPHINGOSINE
  • N-PALMITOYL-D-ERYTHRO-SPHINGOSINE SYNTHETICAL 99+%
  • N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecenyl]-Hexadecanamide
  • N-Palmitoylsphingosine
  • (2S,3R,4E)-2-(Palmitoylamino)-4-octadecene-1,3-diol
  • C16 Ceramide (d18:1/16:0)
  • C16 Ceramide (N-Palmitoylsphingosine, D-erythro)
  • N-PALMITOYL-D-ERYTHRO-SPHINGOSINE;C16 CERAMIDE (D18:1/16:0)
  • Hexadecanamide, N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-
  • N-(1,3-dihydroxyoctadec-4-en-2-yl)hexadecanamide
  • N-[(2S,3S)-1,3-dihydroxyoctadec-4-en-2-yl]hexadecanamide
  • Cer(d18:1/16:0)/N-(hexadecanoyl)-sphing-4-enine
  • N-((2S,3R,E)-1,3-Dihydroxyoctadec-4-en-2-yl)palmitamide
  • C16 Ceramide (Palmitoyl ceramide), Endogenous ceramide
  • <i>N</i>-Palmitoyl-<sc>D</sc>-sphingosine
  • C16 Ceramide, Ceramide NS
  • N-Palmitoyl-D-sphingosine[43799]
  • 24696-26-2
  • 24969-26-2
  • C34H67NO3
  • Mixed Fatty Acids
  • Activators
  • Fatty Acid Derivatives & Lipids
  • Glycerols
  • Protein Kinase Inhibitors and Activators