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KRN7000

Product Name
KRN7000
CAS No.
158021-47-7
Chemical Name
KRN7000
Synonyms
Α-GALACTOSYLCERAMIDE;S34;KRN7000;Α-GALACTOSYL CERAMIDE;Α-GALACTOSYL CERAMIDE;α-Galactosyl CeraMide;α-Galactosyl CeraMide;α-Galactosyl Ceramide;alpha-D-Galactosylceramide;alpha-Galactosylceramide(a-Gal-Cer) (synthetic)
CBNumber
CB0501572
Molecular Formula
C50H99NO9
Formula Weight
858.32
MOL File
158021-47-7.mol
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KRN7000 Property

Melting point:
125-130°C
Boiling point:
939.8±65.0 °C(Predicted)
Density 
1.04±0.1 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
Pyridine (Slightly, Heated)
form 
White solid.
pka
12.92±0.70(Predicted)
color 
White to Pale Beige
Stability:
Hygroscopic
CAS DataBase Reference
158021-47-7
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Safety

WGK Germany 
3
HS Code 
2940.00.6000
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
67576
Product name
(2S,3S,4R)-1-O-(α-D-Galactosyl)-N-hexacosanoyl-2-amino-1,3,4-octadecanetriol
Purity
≥95% (TLC)
Packaging
1mg
Price
$1100
Updated
2024/03/01
TCI Chemical
Product number
G0509
Product name
α-Galactosylceramide
Purity
>95.0%(HPLC)
Packaging
1mg
Price
$198
Updated
2024/03/01
Cayman Chemical
Product number
11208
Product name
KRN 7000
Purity
≥96%
Packaging
500 μg
Price
$197
Updated
2024/03/01
Cayman Chemical
Product number
11208
Product name
KRN 7000
Purity
≥96%
Packaging
1mg
Price
$253
Updated
2024/03/01
Cayman Chemical
Product number
11208
Product name
KRN 7000
Purity
≥96%
Packaging
250μg
Price
$115
Updated
2022/04/27
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KRN7000 Chemical Properties,Usage,Production

Description

KRN 7000 is a potent synthetic α-galactosylceramide, which, in association with the antigen-presenting CD1d protein, activates NKT immune cells. As these cells have important roles in the rejection of malignant tumors and in the regulation of several autoimmune diseases, KRN 7000 has activity in many diseases, including cancer, lupus, diabetes, malaria, and tuberculosis.

Chemical Properties

White Solid

Uses

KRN 7000 is a potent synthetic α-galactosylceramide, which, in association with the antigen-presenting CD1d protein, activates NKT immune cells. As these cells have important roles in the rejection of malignant tumors and in the regulation of several autoimmune diseases, KRN 7000 has activity in many diseases, including cancer, lupus, diabetes, malaria, and tuberculosis.

Uses

Galactosylceramides play an important roles in promoting the regulation of nerve cells, regulating protein kinase C activities and modulating the function of the hormone receptor. It has shown to have significant immunostimulatory and anti-umor activity in mice with liver metastasis of the Colon26 adenocarcinoma.

Definition

ChEBI: A glycophytoceramide having an alpha-D-galactosyl residue at the O-1 position and a hexacosanoyl group attached to the nitrogen.

storage

-20°C

KRN7000 Preparation Products And Raw materials

Raw materials

Preparation Products

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KRN7000 Suppliers

Suzhou Biosyntech Co., Ltd.
Tel
0512-63001269 15720870325
Email
sales2@biosyntech-suzhou.com
Country
China
ProdList
55
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28387
Advantage
80
TCI Europe
Tel
320-37350700
Fax
+32 (0)37350701
Email
sales@tcieurope.eu
Country
Europe
ProdList
23671
Advantage
75
TCI AMERICA
Tel
800-4238616
Fax
+1-888-520-1075 / +1-503-283-1987
Email
sales@tciamerica.com
Country
Americas
ProdList
23653
Advantage
75
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-400-6206333 18521732826
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
ShangHai Caerulum Pharma Discovery Co., Ltd.
Tel
18149758185 18149758185
Email
sales-cpd@caerulumpharma.com
Country
China
ProdList
3466
Advantage
58
Yichang Zhongyitai Trading Co., Ltd.
Tel
0717-6449896 13886658719
Fax
0717-6558598
Email
root@zhongyitai.com
Country
China
ProdList
1977
Advantage
58
Shanghai AECOM Biotechnology Co. , Ltd.
Tel
021-021-20956531 18116226605
Fax
021-20956532
Email
sui@neosunpharm.com
Country
China
ProdList
350
Advantage
55
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View Lastest Price from KRN7000 manufacturers

Hangzhou MolCore BioPharmatech Co.,Ltd.
Product
KRN7000 158021-47-7
Price
US $0.00-0.00/G
Min. Order
1G
Purity
98%
Supply Ability
kgs
Release date
2023-12-29
GlycoPharm.LLC
Product
(2S,3S,4R)-1-O-(α-D-Galactopyranosyl)-N-hexacosanoyl-2-amino-1,3,4-octadecanetriol Synonym:?α-GalCer or KRN7000 158021-47-7
Price
US $0.00/mg
Min. Order
5mg
Purity
97%HPLC
Supply Ability
MG-KG
Release date
2020-03-17

158021-47-7, KRN7000Related Search:


  • (2S,3S,4R)-1-O-(α-D-Galactopyranosyl)-N-hexacosanoyl-2-amino-1,3,4-octadecanetriol Synonym:α-GalCer or KRN7000
  • Α-GALACTOSYLCERAMIDE
  • KRN7000
  • N-[(1S,2S,3R)-1-[(α-D-Galactopyranosyloxy)Methyl]-2,3-dihydroxyheptadecyl]hexacosanaMide
  • α-Galactosyl CeraMide
  • α-Galactosyl CeraMide
  • Α-GALACTOSYL CERAMIDE
  • Α-GALACTOSYL CERAMIDE
  • 1-O-(alpha-D-galactosyl)-N-hexacosanoylphytosphingosine
  • (2S,3S,4R)-1-O-(α-D-Galactosyl)-N-hexacosanoyl-2-amino-1,3,4-octadecanetriol
  • Hexacosanamide, N-[(1S,2S,3R)-1-[(α-D-galactopyranosyloxy)methyl]-2,3-dihydroxyheptadecyl]-
  • alpha-Galactosylceramide(a-Gal-Cer) (synthetic)
  • α-Galactosyl Ceramide
  • 1-O-(α-D-galactosyl)-N-hexacosanoylphytosphingosine
  • S34
  • α-Galactosyl Ceramide Supplier: Funakoshi Co. Ltd.
  • alpha-D-Galactosylceramide
  • N-((2S,3S,4R)-3,4-Dihydroxy-1-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)octadecan-2-yl)hexacosanamide
  • 158021-47-7
  • C50H99NO9
  • Amino Acids & Derivatives
  • Protein Kinase Inhibitors and Activators
  • Amino Acids 13C, 2H, 15N