ChemicalBook > CAS DataBase List > KRN7000

KRN7000

Product Name
KRN7000
CAS No.
158021-47-7
Chemical Name
KRN7000
Synonyms
Α-GALACTOSYLCERAMIDE;S34;KRN7000;Α-GALACTOSYL CERAMIDE;Α-GALACTOSYL CERAMIDE;α-Galactosyl CeraMide;α-Galactosyl CeraMide;α-Galactosyl Ceramide;alpha-D-Galactosylceramide;alpha-Galactosylceramide(a-Gal-Cer) (synthetic)
CBNumber
CB0501572
Molecular Formula
C50H99NO9
Formula Weight
858.32
MOL File
158021-47-7.mol
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KRN7000 Property

Melting point:
125-130°C
Boiling point:
939.8±65.0 °C(Predicted)
Density 
1.04±0.1 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
Pyridine (Slightly, Heated)
form 
White solid.
pka
12.92±0.70(Predicted)
color 
White to Pale Beige
Stability:
Hygroscopic
CAS DataBase Reference
158021-47-7
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Safety

WGK Germany 
3
HS Code 
2940.00.6000
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
67576
Product name
(2S,3S,4R)-1-O-(α-D-Galactosyl)-N-hexacosanoyl-2-amino-1,3,4-octadecanetriol
Purity
≥95% (TLC)
Packaging
1mg
Price
$1100
Updated
2024/03/01
TCI Chemical
Product number
G0509
Product name
α-Galactosylceramide
Purity
>95.0%(HPLC)
Packaging
1mg
Price
$198
Updated
2024/03/01
Cayman Chemical
Product number
11208
Product name
KRN 7000
Purity
≥96%
Packaging
500 μg
Price
$197
Updated
2024/03/01
Cayman Chemical
Product number
11208
Product name
KRN 7000
Purity
≥96%
Packaging
1mg
Price
$253
Updated
2024/03/01
Cayman Chemical
Product number
11208
Product name
KRN 7000
Purity
≥96%
Packaging
250μg
Price
$115
Updated
2022/04/27
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KRN7000 Chemical Properties,Usage,Production

Description

KRN 7000 is a potent synthetic α-galactosylceramide, which, in association with the antigen-presenting CD1d protein, activates NKT immune cells. As these cells have important roles in the rejection of malignant tumors and in the regulation of several autoimmune diseases, KRN 7000 has activity in many diseases, including cancer, lupus, diabetes, malaria, and tuberculosis.

Chemical Properties

White Solid

Uses

KRN 7000 is a potent synthetic α-galactosylceramide, which, in association with the antigen-presenting CD1d protein, activates NKT immune cells. As these cells have important roles in the rejection of malignant tumors and in the regulation of several autoimmune diseases, KRN 7000 has activity in many diseases, including cancer, lupus, diabetes, malaria, and tuberculosis.

Uses

Galactosylceramides play an important roles in promoting the regulation of nerve cells, regulating protein kinase C activities and modulating the function of the hormone receptor. It has shown to have significant immunostimulatory and anti-umor activity in mice with liver metastasis of the Colon26 adenocarcinoma.

Definition

ChEBI: A glycophytoceramide having an alpha-D-galactosyl residue at the O-1 position and a hexacosanoyl group attached to the nitrogen.

storage

-20°C

KRN7000 Preparation Products And Raw materials

Raw materials

Preparation Products

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KRN7000 Suppliers

Suzhou Biosyntech Co., Ltd.
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View Lastest Price from KRN7000 manufacturers

Hangzhou MolCore BioPharmatech Co.,Ltd.
Product
KRN7000 158021-47-7
Price
US $0.00-0.00/G
Min. Order
1G
Purity
98%
Supply Ability
kgs
Release date
2023-12-29
GlycoPharm.LLC
Product
(2S,3S,4R)-1-O-(α-D-Galactopyranosyl)-N-hexacosanoyl-2-amino-1,3,4-octadecanetriol Synonym:?α-GalCer or KRN7000 158021-47-7
Price
US $0.00/mg
Min. Order
5mg
Purity
97%HPLC
Supply Ability
MG-KG
Release date
2020-03-17

158021-47-7, KRN7000Related Search:


  • (2S,3S,4R)-1-O-(α-D-Galactopyranosyl)-N-hexacosanoyl-2-amino-1,3,4-octadecanetriol Synonym:α-GalCer or KRN7000
  • Α-GALACTOSYLCERAMIDE
  • KRN7000
  • N-[(1S,2S,3R)-1-[(α-D-Galactopyranosyloxy)Methyl]-2,3-dihydroxyheptadecyl]hexacosanaMide
  • α-Galactosyl CeraMide
  • α-Galactosyl CeraMide
  • Α-GALACTOSYL CERAMIDE
  • Α-GALACTOSYL CERAMIDE
  • 1-O-(alpha-D-galactosyl)-N-hexacosanoylphytosphingosine
  • (2S,3S,4R)-1-O-(α-D-Galactosyl)-N-hexacosanoyl-2-amino-1,3,4-octadecanetriol
  • Hexacosanamide, N-[(1S,2S,3R)-1-[(α-D-galactopyranosyloxy)methyl]-2,3-dihydroxyheptadecyl]-
  • alpha-Galactosylceramide(a-Gal-Cer) (synthetic)
  • α-Galactosyl Ceramide
  • 1-O-(α-D-galactosyl)-N-hexacosanoylphytosphingosine
  • S34
  • α-Galactosyl Ceramide Supplier: Funakoshi Co. Ltd.
  • alpha-D-Galactosylceramide
  • N-((2S,3S,4R)-3,4-Dihydroxy-1-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)octadecan-2-yl)hexacosanamide
  • 158021-47-7
  • C50H99NO9
  • Amino Acids & Derivatives
  • Protein Kinase Inhibitors and Activators
  • Amino Acids 13C, 2H, 15N