CHITOBIOSE DIHYDROCHLORIDE
- Product Name
- CHITOBIOSE DIHYDROCHLORIDE
- CAS No.
- 577-76-4
- Chemical Name
- CHITOBIOSE DIHYDROCHLORIDE
- Synonyms
- Chitosanbiose;Chitobiose Hydrochloride;Chitobiose 2HCl;Chitotriose 2HCl;Chitobiose Hydrochlorlde;CHITOBIOSE DIHYDROCHLORIDE;Chitosan Dimer extrapure, 98%;Chitobiose Hydrochloride, Chitobiose?2HCl;beta-D-glucosaminyl-(1->4)-aldehydo-D-glucosamine;4-O-(2-Amino-2-deoxy-beta-D-glucosyl)-D-glucosamine
- CBNumber
- CB1424269
- Molecular Formula
- C12H24N2O9
- Formula Weight
- 340.33
- MOL File
- 577-76-4.mol
CHITOBIOSE DIHYDROCHLORIDE Property
- Boiling point:
- 736.2±60.0 °C(Predicted)
- Density
- 1.58±0.1 g/cm3(Predicted)
- pka
- 11.01±0.45(Predicted)
Safety
- Safety Statements
- 24/25
- HS Code
- 29400090
N-Bromosuccinimide Price
- Product number
- 296834
- Product name
- Chitobiose 2HCl
- Packaging
- 5mg
- Price
- $426
- Updated
- 2021/12/16
- Product number
- OC08301
- Product name
- Chitobiose 2HCl
- Packaging
- 50mg
- Price
- $500
- Updated
- 2021/12/16
- Product number
- OC08301
- Product name
- Chitobiose 2HCl
- Packaging
- 100mg
- Price
- $850
- Updated
- 2021/12/16
- Product number
- OC08301
- Product name
- Chitobiose 2HCl
- Packaging
- 5mg
- Price
- $95
- Updated
- 2021/12/16
- Product number
- OC08301
- Product name
- Chitobiose 2HCl
- Packaging
- 10mg
- Price
- $150
- Updated
- 2021/12/16
CHITOBIOSE DIHYDROCHLORIDE Chemical Properties,Usage,Production
Chemical Properties
reducing terminal of N-linked oligosaccharides, lectin inhibitor, lysozyme substrate
Uses
Chitobiose, a chitosan oligosaccharide, is a dimer of β-1,4-linked glucosamine units[1]. Chitobiose has orally activity and high antioxidant activity[2].
Definition
ChEBI: Beta-D-glucosaminyl-(1->4)-aldehydo-D-glucosamine is a member of chitobioses.
in vivo
Chitobiose (30, 100, 300 mg/kg; p.o., single) can enters the circulatory system when given orally[2].
Pharmacokinetic Parameters of Chitobiose in Wistar strain male rats[2].
| PO (30 mg/kg) | PO (100 mg/kg) | PO (300 mg/kg) | |
| Tmax (h) | 0.9 | 1.0 | 1.8 |
| Cpmax (μg/mL) | 1.1 | 4.4 | 6.9 |
| AUC0-4h (μg·h/mL) | 2.5 | 9.0 | 17.6 |
| AUMC0-4h (μg·h^2/mL) | 4.0 | 13.2 | 35.6 |
| MRT (h) | 1.6 | 1.5 | 1.6 |
| MAT (h) | 1.1 | 1.0 | 1.2 |
| ka (h^-1) | 0.95 | 0.99 | 0.96 |
| F1-4h (%) | 1.8 | 2.0 | 1.3 |
| Animal Model: | Wistar strain male rats (7 weeks, 165-185 g)[2] |
| Dosage: | 30, 100, 300 mg/kg |
| Administration: | p.o., single (Pharmacokinetics analysis) |
| Result: | Entered the circulatory system when given orally. |
References
[1] Zhao Q, et al. Chitoheptaose Promotes Heart Rehabilitation in a Rat Myocarditis Model by Improving Antioxidant, Anti-Inflammatory, and Antiapoptotic Properties. Oxid Med Cell Longev. 2020;2020:2394704. Published 2020 Apr 11. DOI:10.1155/2020/2394704
[2] Chen AS, Taguchi T, Okamoto H, et al. Pharmacokinetics of chitobiose and chitotriose administered intravenously or orally to rats. Biol Pharm Bull. 2005;28(3):545-548. DOI:10.1248/bpb.28.545
CHITOBIOSE DIHYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from CHITOBIOSE DIHYDROCHLORIDE manufacturers
- Product
- Chitobiose Dihydrochloride 577-76-4
- Price
- US $0.00/G
- Min. Order
- 10G
- Purity
- 98%min
- Supply Ability
- 30kg/month
- Release date
- 2023-02-14
- Product
- Chitobiose Hydrochloride 577-76-4
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-09-19
- Product
- chitobiose dihydrochloride 577-76-4
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- ≥98%
- Supply Ability
- 100kg
- Release date
- 2019-12-17