ChemicalBook > CAS DataBase List > Carbadox

Carbadox

Product Name
Carbadox
CAS No.
6804-07-5
Chemical Name
Carbadox
Synonyms
CBX;M31;MOD1;gs6244;CARBADO;Mecadox;p25beta;CARBADOX;fortigro;getroxel
CBNumber
CB1425347
Molecular Formula
C11H10N4O4
Formula Weight
262.22
MOL File
6804-07-5.mol
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Carbadox Property

Melting point:
239-240°C
Boiling point:
405.47°C (rough estimate)
Density 
1.3602 (rough estimate)
refractive index 
1.6000 (estimate)
Flash point:
18°(64°F)
storage temp. 
2-8°C
solubility 
DMSO (Slightly, Sonicated)
form 
powder
pka
10.51±0.46(Predicted)
color 
Yellow to Dark Yellow
Water Solubility 
Soluble in 1N NaOH (50 mg/ml), and water (partly).
Stability:
Light Sensitive
CAS DataBase Reference
6804-07-5
EPA Substance Registry System
Hydrazinecarboxylic acid, 2-[(1,4-dioxido-2-quinoxalinyl)methylene]-, methyl ester (6804-07-5)
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Safety

Hazard Codes 
F,T
Risk Statements 
45-11-22
Safety Statements 
53-45
RIDADR 
UN 1325 4.1/PG 2
WGK Germany 
3
RTECS 
FE2779000
HazardClass 
4.1
HS Code 
29339900
Hazardous Substances Data
6804-07-5(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H228Flammable solid

H302Harmful if swallowed

H350May cause cancer

Precautionary statements

P201Obtain special instructions before use.

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P240Ground/bond container and receiving equipment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P405Store locked up.

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N-Bromosuccinimide Price

Alfa Aesar
Product number
J60284
Product name
Carbadox, 98+%
Packaging
25g
Price
$94.65
Updated
2024/03/01
Alfa Aesar
Product number
J60284
Product name
Carbadox, 98+%
Packaging
100g
Price
$235.65
Updated
2024/03/01
Cayman Chemical
Product number
24903
Product name
Carbadox
Purity
≥98%
Packaging
10g
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
24903
Product name
Carbadox
Purity
≥98%
Packaging
25g
Price
$60
Updated
2024/03/01
Cayman Chemical
Product number
24903
Product name
Carbadox
Purity
≥98%
Packaging
50g
Price
$109
Updated
2024/03/01
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Carbadox Chemical Properties,Usage,Production

Chemical Properties

Yellow Crystalline Solid

Originator

Carbadox,Agrimex

Uses

Carbadox has been used to suppress aldosterone production, to study the spread of shiga toxin-producing Escherichia coli (STEC) strains, and to compare different antimicrobial activities. Carbadox is a quinoxaline-di-N-oxide antibiotic that is generally used in feed to swine to prevent dysentery and improve feed efficiency. It inhibits bacteria by intercalation and induction of mutations in bacterial genome.

Definition

ChEBI: Carbadox is a quinoxaline derivative.

Manufacturing Process

A solution of methylcarbazate (48.0 mg) in methanol (250 ml) is added all at once at room temperature to a well stirred solution of 2-formylquinoxaline- 1,4-dioxide (100 g) in methanol (2.5 liters). Two drops of concentrated hydrochloric acid are added. The mixture is stirred for 3 hours then filtered to remove the yellow crystalline product. The crystals of (2- quinoxalinylmethylene)hydrazinecarboxylic acid methyl ester are washed with methanol then air dried; M.P. 234.5-236°C (dec.). Yield=121.8 g. The product is purified by refluxing in chloroform for 2 hours, followed by filtration and air drying; M.P. 239.5-240°C (dec.).
The ultraviolet absorption spectrum (water) exhibits maxima at 236, 251, 303, 366 and 373 nm with extinction coefficients of 11,000, 10,900, 36,400, 16,100 and 16,200, respectively.

brand name

Mecadox (Pfizer).

Therapeutic Function

Antibacterial

Biochem/physiol Actions

Carbadox is a quinoxaline-di-N-oxide antibiotic that is generally used in feed to swine to prevent dysentery and improve feed efficiency. It inhibits bacteria by intercalation and induction of mutations in bacterial genome.

Safety Profile

Moderately toxic by ingestion. Questionable carcinogen with experimental carcinogenic effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of Nox.

Carbadox Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Carbadox manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
Carbadox 6804-07-5
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-19
Hebei Mojin Biotechnology Co., Ltd
Product
Carbadox 6804-07-5
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000tons
Release date
2023-08-14
Career Henan Chemical Co
Product
Carbadox 6804-07-5
Price
US $1.00/kg
Min. Order
1g
Purity
99%
Supply Ability
100KG
Release date
2018-12-25

6804-07-5, CarbadoxRelated Search:


  • 2-formylquinoxaline1,4-dioxidecarbomethoxyhydrazone
  • 3-(2-chinoxalinylmethylen-1,4-dioxid)methylkarbazat
  • carbazicacid,3-(2-quinoxalinylmethylene)-,methylester,n(sup1),n(sup4)-di
  • methyl3-(2-quinoxalinylmethylene)carbazate-n1,n4-dioxide
  • CARBADOX
  • LABOTEST-BB LT00771878
  • 2-(2-quinoxalinylmethylene)hydrazine-carboxylic acid methyl ester n,n'-dioxide
  • 3-[2-QUINOXALINYLMETHYLENE]CARBAZIC ACID METHYL ESTER N,N'-DIOXIDE
  • 2-(methoxycarbonylhydrazonomethyl)quinoxaline 1,4-dioxide
  • methyl 3-(quinoxalin-2-ylmethylene)carbazate 1,4-dioxide
  • CARBADO
  • 2-(2-quinoxalinyl methylene) hydrazine carboxylic acid
  • carabadox
  • Mecadox-S
  • Methyl 3-[2-quinoxalinylmethylene] carbazate N<sup>1</sup>,N<sup>4</sup>-dioxide
  • Hydrazinecarboxylic acid, (1,4-dioxido-2-quinoxalinyl)methylene-, methyl ester
  • 3-(2-chinoxalinylmethylen-1,4-dioxid)methylkarbazat fortigro
  • fortigro
  • getroxel
  • gs6244
  • hydrazinecarboxylicacid,(2-quinoxalinylmethylene)-,methylester,n,n’-diox
  • Hydrazinecarboxylicacid,(2-quinoxalinylmethylene)-,methylester,N,N’-dioxide
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  • Mecadox
  • carbadox (INN) methyl 3-(quinoxalin-2-ylmethylene)carbazate 1,4-dioxide 2-(methoxycarbonylhydrazonomethyl)quinoxaline 1,4-dioxide
  • (2-Quinoxalinylmethylene)hydrazinecarboxylic Acid Methyl Ester N,N'-Dioxide
  • Methyl-3-(2'-quinoxalinylmethylene) carbazate-N,N-dioxide
  • Methyl-3-(2-quinoxanylmethylene)carbazate-N,N'-dioxide
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  • HP1-BETA
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  • Hydrazinecarboxylicacid, 2-[(1,4-dioxido-2-quinoxalinyl)Methylene]-, Methyl ester
  • (E)-2-((2-(Methoxycarbonyl)hydrazono)methyl)quinoxaline 1,4-dioxide
  • Carbadox (Technical Grade)
  • Carbadox in Methanol
  • C10968300 Carbadox
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  • 6804-07-5
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