Terephthalaldehyde
- Product Name
- Terephthalaldehyde
- CAS No.
- 623-27-8
- Chemical Name
- Terephthalaldehyde
- Synonyms
- 1,4-PHTHALALDEHYDE;Terephthaldehyde;1,4-BENZENEDICARBOXALDEHYDE;TEREPHTHALDICARBOXALDEHYDE;P-benzaldehyde;P-PHTHALALDEHYDE;TPAL;Benzene-1,4-dialdehyde;4-Formylbenzaldehyde;Terephtaldehyde
- CBNumber
- CB1425781
- Molecular Formula
- C8H6O2
- Formula Weight
- 134.13
- MOL File
- 623-27-8.mol
Terephthalaldehyde Property
- Melting point:
- 114-116 °C (lit.)
- Boiling point:
- 245-248 °C (lit.)
- Density
- 1,06 g/cm3
- vapor pressure
- 0.25-0.46Pa at 20-25℃
- refractive index
- 1.4800 (estimate)
- Flash point:
- 76 °C
- storage temp.
- Store below +30°C.
- solubility
- 3g/l
- form
- Crystalline Powder
- color
- White to light yellow
- Water Solubility
- 3 g/L (50 ºC)
- Sensitive
- Air Sensitive
- BRN
- 385863
- Cosmetics Ingredients Functions
- PRESERVATIVE
- InChI
- 1S/C8H6O2/c9-5-7-1-2-8(6-10)4-3-7/h1-6H
- InChIKey
- KUCOHFSKRZZVRO-UHFFFAOYSA-N
- SMILES
- [H]C(=O)c1ccc(cc1)C([H])=O
- LogP
- 1 at 20.1℃ and pH6.6-6.8
- CAS DataBase Reference
- 623-27-8(CAS DataBase Reference)
- NIST Chemistry Reference
- 1,4-Benzenedicarboxaldehyde(623-27-8)
- EPA Substance Registry System
- 1,4-Benzenedicarboxaldehyde (623-27-8)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38-36/37
- Safety Statements
- 22-24/25-36-26-37/39
- WGK Germany
- 1
- RTECS
- WZ0430000
- Hazard Note
- Irritant
- TSCA
- TSCA listed
- HS Code
- 29122900
- Storage Class
- 11 - Combustible Solids
- Hazard Classifications
- Eye Irrit. 2
- Hazardous Substances Data
- 623-27-8(Hazardous Substances Data)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- T2207
- Product name
- Terephthalaldehyde
- Purity
- ReagentPlus , 99%
- Packaging
- 5g
- Price
- $41.9
- Updated
- 2025/07/31
- Product number
- T2207
- Product name
- Terephthalaldehyde
- Purity
- ReagentPlus , 99%
- Packaging
- 100g
- Price
- $76.7
- Updated
- 2025/07/31
- Product number
- 8.08617
- Product name
- Terephthaldialdehyde
- Purity
- for synthesis
- Packaging
- 100g
- Price
- $80.9
- Updated
- 2025/07/31
- Product number
- T0010
- Product name
- Terephthalaldehyde
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $31
- Updated
- 2025/07/31
- Product number
- T0010
- Product name
- Terephthalaldehyde
- Purity
- >98.0%(GC)
- Packaging
- 100g
- Price
- $92
- Updated
- 2025/07/31
Terephthalaldehyde Chemical Properties,Usage,Production
Description
Terephthalaldehyde is an aromatic dialdehyde. Theoretically, the two aldehydes of terephthalaldehyde (TPA) are equivalent, so the single or double Schiff base from TPA and d-glucosamine (Glc) may be formed at the same time. It is used as an intermediate for the preparation of dyes and fluorescent whitening agents and in the synthesis of polyimines by reacting with aliphatic diamines. It is also used as a precursor for the preparation of paramagnetic microporous polymeric organic frameworks (POFs) through copolymerization with pyrrole, indole, and carbazole. As a good crosslinking agent, it could used in crosslinked chitosan hydrogel for the selective removal of anionic dyes[1].
Chemical Properties
WHITE TO LIGHT YELLOW CRYSTALLINE POWDER
Uses
Terephthalaldehyde (cas# 623-27-8) is a compound useful in organic synthesis.
Synthesis Reference(s)
Organic Syntheses, Coll. Vol. 3, p. 788, 1955
Tetrahedron Letters, 36, p. 2285, 1995 DOI: 10.1016/0040-4039(95)00191-E
Synthesis
Using p-xylene, carbon tetrachloride, azodiisobutyronitrile and chlorine as raw materials and solvents, chlorination to obtain benzyl chloride, and then oxidized under the catalytic effect of nitric acid and zinc nitrate, the addition of zinc nitrate improves the yield of terephthalaldehyde to more than 89%, and the purity of the product is higher than 99.0%. Chlorination hydrolysis usually uses highly toxic chlorine gas directly, which is very unfriendly to the environment. In order to avoid the direct use of chlorine gas, N-fluorobenzenesulfonamide and sodium chloride were firstly used to react with p-xylene to synthesize p-dichlorobenzene in a highly selective way, and then the crude product of terephthalaldehyde was obtained through the catalytic action of 98% concentrated sulfuric acid and manganese dioxide, and finally the oxidized masterbatch was neutralized by sodium hydroxide and the finished product of terephthalaldehyde was obtained by recrystallization from the mixture of ethanol and water with the yield of terephthalaldehyde of 77% by weight.
Purification Methods
Terephthalaldehyde [623-27-8] M 134.1, m 116o, b 245 -248o/771mm. Crystallise terephthalaldehyde from water. [Beilstein 7 IV 2140.]
References
[1] Weng Q, et al. Controllable Synthesis and Biological Application of Schiff Bases from d-Glucosamine and Terephthalaldehyde. ACS Omega, 2020; 5: 24864–24870.
Terephthalaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
Terephthalaldehyde Suppliers
- Tel
- 13382554777
- 441789033@qq.com
- Country
- China
- ProdList
- 25
- Advantage
- 58
- Tel
- 010-64446226 15773616370
- Fax
- +86 10 64455595
- info@bj-newcenturychem.com
- Country
- China
- ProdList
- 111
- Advantage
- 55
- Tel
- 021-31038972,31038973 17321035817
- Fax
- +86-21-51385350
- sales@harvest-chem.com
- Country
- China
- ProdList
- 2818
- Advantage
- 64
- Tel
- 13396369453 QQ3007939906 18678026865
- Fax
- 0536-2101172
- sdfantai@163.com
- Country
- China
- ProdList
- 908
- Advantage
- 58
- Tel
- 13277095679
- Fax
- 027-65662438
- 1375175909@qq.com
- Country
- China
- ProdList
- 638
- Advantage
- 58
- Tel
- 15380789538
- 2885743537@qq.com
- Country
- China
- ProdList
- 8205
- Advantage
- 58
- Tel
- 17637776888
- 17637776888@163.com
- Country
- China
- ProdList
- 23
- Advantage
- 58
- Tel
- 13176825516; 13176825516
- 78995114@qq.com
- Country
- China
- ProdList
- 83
- Advantage
- 58
- Tel
- 025-52110956 17372769668
- sophia@njhkchem.com
- Country
- China
- ProdList
- 32
- Advantage
- 58
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
View Lastest Price from Terephthalaldehyde manufacturers
- Product
- Terephthalaldehyde 623-27-8
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-13
- Product
- Terephthalaldehyde 623-27-8
- Price
- US $6.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 2000KG/Month
- Release date
- 2024-08-06
- Product
- Terephthalaldehyde 623-27-8
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-10-31