ChemicalBook > CAS DataBase List > 6-Cyanoindole

6-Cyanoindole

Product Name
6-Cyanoindole
CAS No.
15861-36-6
Chemical Name
6-Cyanoindole
Synonyms
1H-indole-6-carbonitrile;6-Cyanoidole;CYANOINDOLE-6;6-CYANOINDOLE;6-Cyanoindole>6-Cyano-1H-indole;6-Cyanoindole ,98%;Ndole-6-carbonitrile;6-Indolecarbonitrile;INDOLE-6-CARBONITRILE
CBNumber
CB1429451
Molecular Formula
C9H6N2
Formula Weight
142.16
MOL File
15861-36-6.mol
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6-Cyanoindole Property

Melting point:
130-132°C
Boiling point:
350.0±15.0 °C(Predicted)
Density 
1.24±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
Dichloromethane, Methanol
pka
15.17±0.30(Predicted)
form 
Solid
color 
Off-White Crystalline
Sensitive 
Air & Light Sensitive
BRN 
116502
InChI
InChI=1S/C9H6N2/c10-6-7-1-2-8-3-4-11-9(8)5-7/h1-5,11H
InChIKey
SZSZDBFJCQKTRG-UHFFFAOYSA-N
SMILES
N1C2=C(C=CC(C#N)=C2)C=C1
CAS DataBase Reference
15861-36-6(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
22-36/37/38
Safety Statements 
22-36/37-26
RIDADR 
3439
HazardClass 
6.1
PackingGroup 
III
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
C2084
Product name
6-Cyanoindole
Purity
>98.0%(GC)
Packaging
5g
Price
$77
Updated
2025/07/31
TCI Chemical
Product number
C2084
Product name
6-Cyanoindole
Purity
>98.0%(GC)
Packaging
25g
Price
$261
Updated
2024/03/01
TRC
Product number
C981780
Product name
6-Cyanoindole
Packaging
2.5g
Price
$70
Updated
2021/12/16
TRC
Product number
C981780
Product name
6-Cyanoindole
Packaging
5g
Price
$105
Updated
2021/12/16
Usbiological
Product number
C8407
Product name
6-Cyanoindole
Packaging
250mg
Price
$340
Updated
2021/12/16
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6-Cyanoindole Chemical Properties,Usage,Production

Chemical Properties

Off-White Crystalline Solid

Uses

6-Cyanoindole (cas# 15861-36-6) is a compound useful in organic synthesis.

Synthesis

939-79-7

64-19-7

15861-36-6

To a stirred solution of 4-methyl-3-nitrobenzonitrile (16.58 g, 102.3 mmol) in 55 mL of N,N-dimethylformamide (DMF) was added N,N-dimethylacetamide (15.24 g, 128.1 mmol). The reaction mixture turned dark red and was subsequently stirred at 110 °C for 3 hours. After completion of the reaction, the solvent was removed under reduced pressure and the residue was dissolved in a mixture of 300 mL of ethanol and 300 mL of acetic acid. The reaction mixture was heated to 60 °C and iron powder (33 g, 594 mmol) was added in batches. The reaction mixture was refluxed for 2 h. After the reaction was completed, it was filtered through a Hyflo pad. Ether was added to the filtrate and the acidic layer was extracted with ether (1×). The ether layers were combined and concentrated in vacuum. The residue was purified by silica gel column chromatography using dichloromethane as eluent to give 7.02 g (48% yield) of 6-cyanoindaha solid.

References

[1] Patent: US2006/122189, 2006, A1. Location in patent: Page/Page column 20

6-Cyanoindole Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 6-Cyanoindole manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
6-Cyanoindole 15861-36-6
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-20
Henan Bao Enluo International TradeCo.,LTD
Product
6-Cyanoindole 15861-36-6
Price
US $100.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000tons
Release date
2023-08-07
Honest Joy Holdings Limited
Product
6-Cyanoindole 15861-36-6
Price
US $0.00/KG
Min. Order
1KG
Purity
98.8%
Supply Ability
100 tons
Release date
2022-02-08

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