3-(2-PYRIDYL)-5,6-DIPHENYL-1,2,4-TRIAZINE
- Product Name
- 3-(2-PYRIDYL)-5,6-DIPHENYL-1,2,4-TRIAZINE
- CAS No.
- 1046-56-6
- Chemical Name
- 3-(2-PYRIDYL)-5,6-DIPHENYL-1,2,4-TRIAZINE
- Synonyms
- PDT;TIMTEC-BB SBB008869;3-(2-PYRIDYL)-5,6-DIPHENYLTRIAZINE;3-(2-Pyridinyl)-5,6-diphenyl-as-triazine;as-Triazine, 5,6-diphenyl-3-(2-pyridyl)-;5,6-DIPHENYL-3-(2-PYRIDYL)-1,2,4-TRIAZINE;3-(2-PYRIDYL)-5,6-DIPHENYL-1,2,4-TRIAZINE;4-triazine,5,6-diphenyl-3-(2-pyridinyl)-2;5,6-Ddiphenyl-3-(2-pyridyl)-1,2,4-triazine;3-(2-Pyridinyl)-5,6-diphenyl-1,2,4-triazine
- CBNumber
- CB1431610
- Molecular Formula
- C20H14N4
- Formula Weight
- 310.35
- MOL File
- 1046-56-6.mol
3-(2-PYRIDYL)-5,6-DIPHENYL-1,2,4-TRIAZINE Property
- Melting point:
- 191-193 °C (lit.)
- Boiling point:
- 440.52°C (rough estimate)
- Density
- 1.2028 (rough estimate)
- refractive index
- 1.6400 (estimate)
- storage temp.
- Inert atmosphere,Room Temperature
- form
- powder to crystal
- pka
- -0.06±0.63(Predicted)
- color
- Light yellow to Yellow to Orange
- Water Solubility
- Soluble in water.
- BRN
- 542151
- Stability:
- Stable. Incompatible with strong acids, strong oxidizing agents.
- CAS DataBase Reference
- 1046-56-6(CAS DataBase Reference)
- EPA Substance Registry System
- 1,2,4-Triazine, 5,6-diphenyl-3-(2-pyridinyl)- (1046-56-6)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 160415
- Product name
- 3-(2-Pyridyl)-5,6-diphenyl-1,2,4-triazine
- Purity
- ≥99%
- Packaging
- 5g
- Price
- $108
- Updated
- 2024/03/01
- Product number
- D1201
- Product name
- 5,6-Diphenyl-3-(2-pyridyl)-1,2,4-triazine
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 1g
- Price
- $23
- Updated
- 2024/03/01
- Product number
- B24601
- Product name
- 5,6-Diphenyl-3-(2-pyridyl)-1,2 4-triazine, 99%
- Packaging
- 1g
- Price
- $31.65
- Updated
- 2024/03/01
- Product number
- B24601
- Product name
- 5,6-Diphenyl-3-(2-pyridyl)-1,2 4-triazine, 99%
- Packaging
- 5g
- Price
- $100.65
- Updated
- 2024/03/01
- Product number
- B24601
- Product name
- 5,6-Diphenyl-3-(2-pyridyl)-1,2 4-triazine, 99%
- Packaging
- 25g
- Price
- $405
- Updated
- 2024/03/01
3-(2-PYRIDYL)-5,6-DIPHENYL-1,2,4-TRIAZINE Chemical Properties,Usage,Production
Chemical Properties
yellow powder
Uses
3-(2-Pyridyl)-5,6-diphenyl-1,2,4-triazine was employed as chromogenic-extraction reagent during spectrophotometric determination of iron in acids and acidic solutions. It was also employed as precolumn derivatizing reagent in the HPLC method with UV absorbance detection for the Fe(II) determination.
Indications
PDT with 20% ALA may be used for the treatment of actinic keratoses. The product is marketed as Levulan Kerastick (DUSA Pharmaceuticals, Valhalla, New York). The ALA is applied diffusely over the field with an applicator; the patient returns 1 to 3 hours later and is exposed to an activating light source. Once exposed to the light, ALA produces singlet oxygen, which damages the cell membrane. Sixty-six percent of patients had total clearing of lesions at 8 weeks using blue light exposure for 15 minutes. Patients experience a burning pain but heal with an excellent cosmetic result. Photosensitivity lasts for 24 hours. An optional regimen is to apply ALA only to visible actinic keratoses; however, this method will not treat subclinical lesions. A variety of lasers and light sources can be used to activate the ALA, including blue light, yellow light, and broadband light; however, many details remain to be worked out, such as the optimal incubation times for the ALA when using each of the various light sources.
Definition
ChEBI: 5,6-diphenyl-3-(2-pyridyl)-1,2,4-triazine is a member of 1,2,4-triazines.
General Description
3-(2-Pyridyl)-5,6-diphenyl-1,2,4-triazine (PDT) reacts with Cu(II) perchlorate in ethanol to yield [Cu(PDT)2(ClO4)2].
Purification Methods
Purify it by repeated recrystallisation from EtOH/dimethylformamide. It is a reagent for estimating Fe(II) and Ru(II). [Chriswell & Schilt Anal Chem 46 992 1974, Kamra & Ayers Anal Chem 78 423 1975.]
3-(2-PYRIDYL)-5,6-DIPHENYL-1,2,4-TRIAZINE Preparation Products And Raw materials
Raw materials
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