ChemicalBook > CAS DataBase List > 1,2,4-Triazine

1,2,4-Triazine

Product Name
1,2,4-Triazine
CAS No.
290-38-0
Chemical Name
1,2,4-Triazine
Synonyms
as-Triazine;1,2,5-Triazine;1,2,4-Triazine (>90%)
CBNumber
CB81237850
Molecular Formula
C3H3N3
Formula Weight
81.08
MOL File
290-38-0.mol
More
Less

1,2,4-Triazine Property

Boiling point:
197℃
Density 
1.173
refractive index 
1.5060 (estimate)
Flash point:
92℃
storage temp. 
2-8°C
solubility 
Chloroform (Slightly, Heated, Sonicated), DMSO (Slightly, Heated, Sonicated)
form 
Gel
pka
0.98±0.63(Predicted)
color 
Very Dark Orange to Very Dark Brown
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
CHM0376372
Product name
1,2,4-TRIAZINE
Purity
95.00%
Packaging
5MG
Price
$502.41
Updated
2021/12/16
J&W Pharmlab
Product number
95R0049
Product name
[1,2,4]Triazine
Purity
96%
Packaging
500mg
Price
$549
Updated
2021/12/16
Crysdot
Product number
CD11152812
Product name
1,2,4-Triazine
Purity
95+%
Packaging
1g
Price
$842
Updated
2021/12/16
Crysdot
Product number
CD11152812
Product name
1,2,4-Triazine
Purity
95+%
Packaging
5g
Price
$2352
Updated
2021/12/16
More
Less

1,2,4-Triazine Chemical Properties,Usage,Production

Description

1,2,4-Triazine is an electron-deficient heteroaromatic azadiene capable of participation in inverse electron demand Diels-Alder reactions with electron-rich dienophiles.

Uses

1,2,4-Triazine (>90%) is used in improvements of pesticide formulations with lactamides. 1,2,4-triazines scaffold-valuable lead molecules possess diverse pharmacological activities, easy synthetic routes for synthesis and attracted researchers for development of new chemotherapeutic agents in human and mouse model.

Definition

ChEBI: 1,2,4-triazine is a triazine and a member of 1,2,4-triazines.

Synthesis

1,2,4-Triazine is prepared by a cooled (-75 °C) solution of monomeric Glyoxal (90.0 mmol) in absolute MeOH (200 mL) is added to a solution of formamidrazone hydrochloride (40 mmol) in absolute MeOH (300 mL) at -50 °C. Et3N (200 mmol) is added and the resulting reaction mixture is allowed to stand at 25 °C for 24 h. The MeOH is removed in vacuo at 20 °C and the residue extracted with Et2O (peroxide free, 5×). Vacuum distillation of the residue after evaporation of the Et2O affords 1,2,4-triazine (bp 25-28 °C/0.5 mmHg).

storage

Best stored at 0 °C or below. It is stable to acid, less stable to base, and is hygroscopic; should be stored under anhydrous conditions since it reacts slowly with water and protic solvents.

1,2,4-Triazine Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

1,2,4-Triazine Suppliers

Atop-Pharma (Shanghai) Technology Co., Ltd.
Tel
+86 (21) 5196-9732
Fax
+86 (21) 5196-9733
Country
China
ProdList
996
Advantage
57
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66113011 18112977050
Email
cb6@aikonchem.com
Country
China
ProdList
16684
Advantage
50
Springchem New Material Technology Co.,Ltd
Tel
021-52836897 13917661608
Email
info@spring-chem.com
Country
China
ProdList
1967
Advantage
58
Career Henan Chemica Co
Tel
+86-0371-86658258 +8613203830695
Fax
0371-86658258
Email
laboratory@coreychem.com
Country
China
ProdList
30236
Advantage
58
CONIER CHEM AND PHARMA LIMITED
Tel
+8618523575427
Email
sales@conier.com
Country
China
ProdList
49374
Advantage
58
Shandong Mingde Biotechnology Co., Ltd
Tel
18560864701
Email
1054234218@qq.com
Country
China
ProdList
4500
Advantage
58
Zhengzhou Converging Chemical Co. LTD
Tel
0371-037153399770 18037166334
Email
2853031800@qq.com
Country
China
ProdList
3843
Advantage
58
Shanghai Haohong Scientific Co., Ltd.
Tel
400-400-8210725 17717813675;
Email
malulu@leyan.com
Country
China
ProdList
39990
Advantage
58
Shanghai Kaisen Biotechnology Co., Ltd
Tel
17558870519
Email
3549952815@qq.com
Country
China
ProdList
2992
Advantage
58
Alchem Pharmtech,Inc.
Tel
8485655694
Email
sales@alchempharmtech.com
Country
United States
ProdList
63687
Advantage
58