ChemicalBook > CAS DataBase List > 1,2,4-Triazine

1,2,4-Triazine

Product Name
1,2,4-Triazine
CAS No.
290-38-0
Chemical Name
1,2,4-Triazine
Synonyms
as-Triazine;1,2,5-Triazine;1,2,4-Triazine (>90%)
CBNumber
CB81237850
Molecular Formula
C3H3N3
Formula Weight
81.08
MOL File
290-38-0.mol
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1,2,4-Triazine Property

Boiling point:
197℃
Density 
1.173
refractive index 
1.5060 (estimate)
Flash point:
92℃
storage temp. 
2-8°C
solubility 
Chloroform (Slightly, Heated, Sonicated), DMSO (Slightly, Heated, Sonicated)
form 
Gel
pka
0.98±0.63(Predicted)
color 
Very Dark Orange to Very Dark Brown
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
CHM0376372
Product name
1,2,4-TRIAZINE
Purity
95.00%
Packaging
5MG
Price
$502.41
Updated
2021/12/16
J&W Pharmlab
Product number
95R0049
Product name
[1,2,4]Triazine
Purity
96%
Packaging
500mg
Price
$549
Updated
2021/12/16
Crysdot
Product number
CD11152812
Product name
1,2,4-Triazine
Purity
95+%
Packaging
1g
Price
$842
Updated
2021/12/16
Crysdot
Product number
CD11152812
Product name
1,2,4-Triazine
Purity
95+%
Packaging
5g
Price
$2352
Updated
2021/12/16
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1,2,4-Triazine Chemical Properties,Usage,Production

Description

1,2,4-Triazine is an electron-deficient heteroaromatic azadiene capable of participation in inverse electron demand Diels-Alder reactions with electron-rich dienophiles.

Uses

1,2,4-Triazine (>90%) is used in improvements of pesticide formulations with lactamides. 1,2,4-triazines scaffold-valuable lead molecules possess diverse pharmacological activities, easy synthetic routes for synthesis and attracted researchers for development of new chemotherapeutic agents in human and mouse model.

Definition

ChEBI: 1,2,4-triazine is a triazine and a member of 1,2,4-triazines.

Synthesis

1,2,4-Triazine is prepared by a cooled (-75 °C) solution of monomeric Glyoxal (90.0 mmol) in absolute MeOH (200 mL) is added to a solution of formamidrazone hydrochloride (40 mmol) in absolute MeOH (300 mL) at -50 °C. Et3N (200 mmol) is added and the resulting reaction mixture is allowed to stand at 25 °C for 24 h. The MeOH is removed in vacuo at 20 °C and the residue extracted with Et2O (peroxide free, 5×). Vacuum distillation of the residue after evaporation of the Et2O affords 1,2,4-triazine (bp 25-28 °C/0.5 mmHg).

storage

Best stored at 0 °C or below. It is stable to acid, less stable to base, and is hygroscopic; should be stored under anhydrous conditions since it reacts slowly with water and protic solvents.

1,2,4-Triazine Preparation Products And Raw materials

Raw materials

Preparation Products

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1,2,4-Triazine Suppliers

Atop-Pharma (Shanghai) Technology Co., Ltd.
Tel
+86 (21) 5196-9732
Fax
+86 (21) 5196-9733
Country
China
ProdList
996
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57
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66028182 18626450290
Email
yftan@aikonchem.com
Country
China
ProdList
16679
Advantage
50
Shanghai Rlavie Technology Co., Ltd.
Tel
21-67759270 17717059219
Fax
QQ:1479352695
Email
sales@rlavie.com
Country
China
ProdList
1620
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55
Springchem New Material Technology Co.,Ltd
Tel
021-52836897 13917661608
Email
info@spring-chem.com
Country
China
ProdList
2023
Advantage
58
Career Henan Chemica Co
Tel
+86-0371-86658258 +8613203830695
Fax
0371-86658258
Email
laboratory@coreychem.com
Country
China
ProdList
30229
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58
CONIER CHEM AND PHARMA LIMITED
Tel
+8618523575427
Email
sales@conier.com
Country
China
ProdList
49975
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58
JW & Y Pharmlab Co., Ltd.
Tel
021-64340559 13651849907
Fax
021-64345308
Email
xinyu_shi@jwypharmlab.com.cn
Country
China
ProdList
9381
Advantage
58
Zhengzhou Converging Chemical Co. LTD
Tel
0371-53399770 18037166334
Email
2853031800@qq.com
Country
China
ProdList
5873
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58
Shanghai Kaisen Biotechnology Co., Ltd
Tel
17558870519
Email
3549952815@qq.com
Country
China
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2312
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58
Baynoe chem Co.,Ltd
Tel
021-34783353 15572194250
Email
1197363448@qq.com
Country
China
ProdList
1295
Advantage
58